Results 121 to 130 of about 13,627,543 (246)

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

open access: yesMolecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu   +3 more
wiley   +1 more source

Download the Complete Issue (14MB)

open access: yes, 2017
Issue, Complete, Complete Issue
core   +1 more source

CEACAM1 participation in breast cancer progression

open access: yesMolecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin   +3 more
wiley   +1 more source

Download the Complete Issue (22MB)

open access: yes, 2018
Issue, Complete, Complete Issue
core   +1 more source

National Guidelines on Referral and Forensic Clinical Examination Following Rape and Sexual Assault (Ireland).

open access: yes, 2018
National Guidelines on Referral and Forensic Clinical Examination Following Rape and Sexual Assault (Ireland) by the Sexual Assault Response ...
Sexual Assault Response Team (SART)
core  

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

open access: yesMolecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas   +16 more
wiley   +1 more source

Download the Complete Issue (26MB)

open access: yes, 2018
Issue, Complete, Complete Issue
core   +1 more source

Connecticut State Emergency Response Commission [web site] [Harvested on 2011: Jun. 1]

open access: yes, 2011
Updated irregularly; Began in 2002?; Title from home page (publisher's Web site, viewed June 1, 2011).; At head of title: State of Connecticut.; Official website of the Connecticut State Emergency Response Commission.

core  

Connecticut State Emergency Response Commission [web site] [Harvested on 2013: Aug. 12]

open access: yes, 2013
Updated irregularly; Began in 2002?; Title from home page (publisher's Web site, viewed June 1, 2011).; At head of title: State of Connecticut.; Official website of the Connecticut State Emergency Response Commission.

core   +1 more source

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