Results 21 to 30 of about 13,627,543 (246)

Locally advanced rectal cancer with dMMR/MSI-H may be excused from surgery after neoadjuvant anti-PD-1 monotherapy: a multiple-center, cohort study

Frontiers in Immunology, 2023
ObjectiveExamine patients with locally advanced rectal cancer (LARC) with deficient mismatch repair (dMMR) or microsatellite instability-high (MSI-H) who received neoadjuvant immunotherapy (nIT), and compare the outcomes of those who chose a watch-and ...
Renfang Yang, Tao Wu, Jiehai Yu, Xinyi Cai, Guoyu Li, Xiangshu Li, Weixin Huang, Ya Zhang, Yuqin Wang, Xudong Yang, Yongping Ren, Ruixi Hu, Qing Feng, Peirong Ding, Xuan Zhang, Yunfeng Li   +15 more
doaj   +1 more source

“Watch and wait” approach in rectal cancer patients following complete clinical response to neoadjuvant chemoradiotherapy does not compromise oncologic outcomes

The Turkish Journal of Gastroenterology, 2019
Background/Aims: Although standart treatment for non-metastatic locally advanced rectal cancer includes neoadjuvant chemoradiation followed by surgical resection, patients who have achieved complete clinical response can be followed up without surgery ...
Gürel Neşşar, Ali Eba Demirbağ, Hasan Cem Mısırlıoğlu, Semih Sezer   +3 more
doaj   +1 more source

Complete closure of a colo-duodenal fistula in a patient with advanced ascending colon cancer after pembrolizumab combined with radiation therapy: a case report

Surgical Case Reports, 2021
Background A colo-duodenal fistula is a very rare complication of colon cancer that presents with not only severe clinical symptoms, but a poor prognosis due to locally advanced cancer.
Tetsuro Tominaga, Takashi Nonaka, Akiko Fukuda, Masaaki Moriyama, Shosaburo Oyama, Mitsutoshi Ishii, Masato Nishimuta, Yuta Fujise, Terumitsu Sawai, Takeshi Nagayasu   +9 more
doaj   +1 more source

Clinical Tools for Rectal Cancer Response Assessment following Neoadjuvant Treatment in the Era of Organ Preservation

, 2023
Local tumor response evaluation following neoadjuvant treatment(s) in rectal adenocarcinoma requires a multi-modality approach including physical and endoscopic evaluations, rectal protocoled MRI, and cross-sectional imaging.
Sophie Dessureault, Seth Felder, Julian Sanchez, Amalia J. Stefanou   +3 more
core   +1 more source

Analysis of the asymptotic response of complete contacts [PDF]

, 2023
Complete contacts are a rich area of study and are of significant interest. These contacts arise when one of the contacting bodies has a sharp corner, such as if machining burrs have not been removed, or if previous damage has resulted in material loss ...
Riddoch, Daniel
core   +1 more source

Impact of Sarcopenia on Treatment Outcomes and Toxicity in Locally Advanced Rectal Cancer

Medicina
Background and Objectives: Sarcopenia, a condition characterized by muscle mass loss, is prevalent in up to 68% of rectal cancer patients and has been described as a negative prognostic factor, impacting overall survival and tumor response.
Sebastian Curcean, Alexandra Gherman, Alexandru Tipcu, Zsolt Fekete, Alina-Simona Muntean, Andra Curcean, Rares Craciun, Stefan Stanciu, Alexandru Irimie   +8 more
doaj   +1 more source

Treatment Patterns and Outcomes of Ovarian Cancer in Different Centres of Karachi

Pakistan Armed Forces Medical Journal
Objective: To evaluate the treatment pattern i.e. either upfront surgery followed by adjuvant chemotherapy or upfront neoadjuvant chemotherapy followed by surgery and outcomes of advance ovarian cancer in different hospitals of Karachi.
Perwasha Kerio, Ghulam Haider, Khalil Ahmed, Saima Zahoor, Hina Perveen, Muhammad Hayat   +5 more
doaj   +1 more source

Surgery may not benefit patients with locally advanced rectal cancer who achieved clinical complete response following neoadjuvant chemoradiotherapy

Asian Journal of Surgery, 2022
Purpose: We compared the long-term outcome of the watch and wait (WW) strategy and surgery in patients with locally advanced rectal cancer. Patients and methods: This prospective cohort study included 84 patients who achieved clinical complete response ...
Zihan Han, Ming Li, Jiajia Chen, Dengbo Ji, Tiancheng Zhan, Yifan Peng, Weicheng Xue, Yongheng Li, Yong Cai, Yingshi Sun, Qi Wu, Changzheng Du, Jin Gu   +12 more
doaj   +1 more source

Ovarian Sex Cord Stromal Tumors in Children and Adolescents—The European Standard Clinical Practice Recommendations

Pediatric Blood &Cancer, EarlyView.
ABSTRACT As part of the European Cooperative Study Group for Paediatric Rare Tumours initiative, we developed standard clinical practice guidelines for ovarian sex cord stromal tumors, based on comprehensive national and international cohort analyses, literature review, and a final expert consensus conference.
Dominik T. Schneider, Kris‐Ann Schultz, Nora Schnitzler, Michael Abele, Tal Ben‐Ami, Ewa Bien, Gianni Bisogno, Ines B. Brecht, Maja Cesen, Andrea Ferrari, Michaela Kuhlen, Malgorzata A. Krawczyk, Ricardo Lopez‐Almaraz, Yves Reguerre, Calogero Virgone, Daniel Orbach   +15 more
wiley   +1 more source

Expression of CXCL10 is associated with response to radiotherapy and overall survival in squamous cell carcinoma of the tongue [PDF]

, 2014
Five-year survival for patients with oral cancer has been disappointingly stable during the last decades, creating a demand for new biomarkers and treatment targets.
Philip John Coates, Torben Wilms, Laurell, Göran,, Rentoft, Matilda,, Coates, Philip John, Matilda Rentoft, Lotta Loljung, Göran Laurell, Karin Nylander, Rentoft, Matilda, Laurell, Göran, Wilms, Torben, Loljung, Lotta, Nylander, Karin, Loljung, Lotta,, Wilms, Torben,, Nylander, Karin,, Coates, Philip John,   +17 more
core   +1 more source