Results 31 to 40 of about 2,967,291 (296)

Factors influencing response to ingenol mebutate therapy for actinic keratosis of face and scalp [PDF]

, 2017
AIM To determine factors independently influencing response to ingenol mebutate therapy and assess efficacy on clinical setting of non-hypertrophic non-hyperkeratotic actinic keratosis (AK).
Balduzzi, Veronica, Bernardini, Nicoletta, La Torre, Giuseppe, Mambrin, Alessandra, Marchesiello, Anna, Potenza, Concetta, Proietti, Ilaria, Skroza, Nevena, Tolino, Ersilia, Zuber, Sara   +9 more
core   +1 more source

Clinician emotional response toward narcissistic patients. A preliminary report [PDF]

, 2015
Patients with narcissistic personality disorder (NPD) are among the most difficult to treat in therapy, especially for their strong resistance to treatment and several difficulties in establishing a therapeutic relationship characterized by intimacy ...
Colli, Antonello, Lingiardi, Vittorio, Muzi, Laura, Tanzilli, Annalisa   +3 more
core   +2 more sources

Multiple gene aberrations and breast cancer: lessons from super-responders. [PDF]

, 2015
BackgroundThe presence of multiple molecular aberrations in patients with breast cancer may correlate with worse outcomes.Case presentationsWe performed in-depth molecular analysis of patients with estrogen receptor-positive, HER2-negative, hormone ...
Atkins, Johnique T, Janku, Filip, Kurzrock, Razelle, Moulder, Stacy L, Stephens, Philip J, Wheler, Jennifer J, Yelensky, Roman   +6 more
core   +2 more sources

Complete closure of a colo-duodenal fistula in a patient with advanced ascending colon cancer after pembrolizumab combined with radiation therapy: a case report

Surgical Case Reports, 2021
Background A colo-duodenal fistula is a very rare complication of colon cancer that presents with not only severe clinical symptoms, but a poor prognosis due to locally advanced cancer.
Tetsuro Tominaga, Takashi Nonaka, Akiko Fukuda, Masaaki Moriyama, Shosaburo Oyama, Mitsutoshi Ishii, Masato Nishimuta, Yuta Fujise, Terumitsu Sawai, Takeshi Nagayasu   +9 more
doaj   +1 more source

Surgery may not benefit patients with locally advanced rectal cancer who achieved clinical complete response following neoadjuvant chemoradiotherapy

Asian Journal of Surgery, 2022
Purpose: We compared the long-term outcome of the watch and wait (WW) strategy and surgery in patients with locally advanced rectal cancer. Patients and methods: This prospective cohort study included 84 patients who achieved clinical complete response ...
Zihan Han, Ming Li, Jiajia Chen, Dengbo Ji, Tiancheng Zhan, Yifan Peng, Weicheng Xue, Yongheng Li, Yong Cai, Yingshi Sun, Qi Wu, Changzheng Du, Jin Gu   +12 more
doaj   +1 more source

Screening vaccine formulations for biological activity using fresh human whole blood. [PDF]

, 2014
Understanding the relevant biological activity of any pharmaceutical formulation destined for human use is crucial. For vaccine-based formulations, activity must reflect the expected immune response, while for non-vaccine therapeutic agents, such as ...
Aboutorabian, Sepideh, Ausar, Salvador F, Brookes, Roger H, Dockrell, Hazel M, Ha, Yukyung, Hakimi, Jalil, Hasija, Manvi, Rahman, Nausheen, Smith, Steven G, Todryk, Stephen M   +9 more
core   +1 more source

Superhuman? Perceptions of accelerated students and graduates working in health care [PDF]

, 2014
Background: Accelerated university courses were developed in response to consumer demand and educational advances, yet a lack of research exists related to the impact of accelerated health care courses in the United Kingdom.
American Association of Colleges of Nursing, American Association of Colleges of Nursing, Bentley, Blythe, Caldwell, Cangelosi, Cangelosi, Cangelosi, Chartered Society of Physiotherapy, Craik, Glasgow Caledonian University, Grounds, Halkett, Health Professions Council, Howkins, Husson, James Milligan, Kasworm, Kohn, Meyer, Miklancie, Neill, Neill, Nursing and Midwifery Council, Oermann, Ouellet, Quality Assurance Agency for Higher Education, Scott, Seifert, Seldomridge, Smith, Stewart, Swenson, Traub, Wilcock, Wilkinson, Wlodkowski, Wu, Youssef   +38 more
core   +1 more source

Metastatic porocarcinoma achieving complete radiological and clinical response with pembrolizumab

BMJ Case Reports, 2019
A 67-year-old woman presented in 2012 with a crusty nodule on the left lower limb. Histopathological examination at this time reported a poorly differentiated squamous cell carcinoma (SCC). Two years later, she underwent lymphadenectomy and radiotherapy due to unilateral inguinal and pelvic sidewall nodal metastases.
Karla A Lee, Margherita Cioni, Alistair Robson, Veronique Bataille   +3 more
openaire   +3 more sources

Neoadjuvant FOLFOXIRI prior to chemoradiotherapy for high-risk (“ugly”) locally advanced rectal cancer: study protocol of a single-arm, multicentre, open-label, phase II trial (MEND-IT)

BMC Cancer, 2022
Background The presence of mesorectal fascia (MRF) invasion, grade 4 extramural venous invasion (EMVI), tumour deposits (TD) or extensive or bilateral extramesorectal (lateral) lymph nodes (LLN) on MRI has been suggested to identify patients with ...
K. van den Berg, D. P. Schaap, E. L. K. Voogt, T. E. Buffart, H. M. W. Verheul, J. W. B. de Groot, C. Verhoef, J. Melenhorst, J. M. L. Roodhart, J. H. W. de Wilt, H. L. van Westreenen, A. G. J. Aalbers, M. van ‘t Veer, C. A. M. Marijnen, J. Vincent, L. H. J. Simkens, N. A. J. B. Peters, M. Berbée, I. M. Werter, P. Snaebjornsson, H. M. U. Peulen, I. G. van Lijnschoten, M. J. Roef, G. A. P. Nieuwenhuijzen, J. G. Bloemen, J. M. W. E. Willems, G. J. M. Creemers, J. Nederend, H. J. T. Rutten, J. W. A. Burger   +29 more
doaj   +1 more source

Best time to assess complete clinical response after chemoradiotherapy in squamous cell carcinoma of the anus (ACT II): a post-hoc analysis of randomised controlled phase 3 trial [PDF]

, 2017
Background: Guidelines for anal cancer recommend assessment of response at 6–12 weeks after starting treatment. Using data from the ACT II trial, we determined the optimum timepoint to assess clinical tumour response after chemoradiotherapy. Methods: The
ACT II study group, Adab, Fawzi, Beare, Sandy, Begum, Rubina, Benstead, Kim, Cunningham, David, Gynne-Jones, Robert, Hackshaw, Allan, Harte, Robert J., Kadalayil, Latha, Meadows, Helen, Seabag-Montefiore, David, Stewart, Jill   +12 more
core   +3 more sources