Results 211 to 220 of about 3,116,882 (359)

Peripheral retinal degenerations: multimodal imaging-guided risk stratification and clinical decision-making. [PDF]

Front Ophthalmol (Lausanne)
Babović S, Maletin N, Denda N.
europepmc   +1 more source

Decision-Making in Clinical Medicine

Journal of the Royal College of Physicians of London, 1970
openaire   +2 more sources

MITF maintains genome stability in nonmelanocyte lineages

Molecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir, Adrián López García de Lomana, Thejus B. Venkatesh, Kritika Kirty, Snaevar Sigurdsson, Linda Vidarsdottir, Ramile Dilshat, Erla Sveinbjornsdottir, Snaedis Ragnarsdottir, Daniel H Magnusson, Maria R. Bustos, Eirikur Steingrimsson, Thorkell Gudjonsson, Stefan Sigurdsson   +13 more
wiley   +1 more source

Clinical Decision-Making Case: Febrile Infant. [PDF]

J Educ Teach Emerg Med
Maupin C, Anand A, Hickam G, Nesbit D.
europepmc   +1 more source

Clinical Decision Making [PDF]

Journal of Hand Therapy, 1993
openaire   +1 more source

HER2 Testing and Clinical Decision Making in Gastroesophageal Adenocarcinoma: Guideline From the College of American Pathologists, American Society for Clinical Pathology, and the American Society of Clinical Oncology.

Journal of Clinical Oncology, 2017
Angela N. Bartley, M. Washington, Carol Colasacco, Christina B. Ventura, Nofisat Ismaila, A. Benson, A. Carrato, M. Gulley, D. Jain, S. Kakar, H. Mackay, C. Streutker, Laura H. Tang, M. Troxell, J. Ajani   +14 more
semanticscholar   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Clinical Decision-Making Case: Pulmonary Embolism. [PDF]

J Educ Teach Emerg Med
Lee JH, Herman L.
europepmc   +1 more source

ESMO Consensus Guidelines for management of patients with colon and rectal cancer. a personalized approach to clinical decision making.

Annals of Oncology, 2012
H. Schmoll, E. Cutsem, A. Stein, V. Valentini, B. Glimelius, B. Glimelius, K. Haustermans, B. Nordlinger, C. Velde, J. Balmaña, J. Reguła, I. Nagtegaal, R. Beets-Tan, D. Arnold, F. Ciardiello, P. Hoff, D. Kerr, C.-H. Köhne, R. Labianca, T. Price, W. Scheithauer, A. Sobrero, J. Tabernero, D. Aderka, S. Barroso, G. Bodoky, J. Douillard, H. E. Ghazaly, J. Gallardo, A. Garin, R. Glynne-Jones, K. Jordan, A. Meshcheryakov, D. Papamichail, P. Pfeiffer, I. Souglakos, S. Turhal, A. Cervantes   +37 more
semanticscholar   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source