Results 281 to 290 of about 3,116,882 (359)

Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment

Aging and Cancer, EarlyView.
Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey, Murilo Ramos Rocha, Cheyenne Palm, Vania Wang, Denys Balandin, Ethan Black, Kevin Y. Zhang, Fan Huang, Daniel J. Zabransky, Yash Chhabra, Mareike Peters, Gabriel Ghiaur, Ashani Weeraratna   +12 more
wiley   +1 more source

Distinguishing anchoring from confirmation bias in diagnostic vignette studies: methodological implications for clinical decision-making. [PDF]

Front Public Health
Martínez JA, Martínez L.
europepmc   +1 more source

Natural Products as Geroprotective Modulators in Diabetic Nephropathy: A Mechanistic Framework Integrating Aging Hallmarks and the AMPK–SIRT1–Nrf2 Axis

Aging and Cancer, EarlyView.
Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu, Latif Adams, Eunice Ampem‐Danso, Justice Kumi, Abigail Aning, Fatima Hamidu, Mustapha Abdul Mumin Mohammed, Ayuba Nii Darku Ankrah, Seth Kwabena Amponsah   +8 more
wiley   +1 more source

Clinical pharmacology consultations and their implementation in clinical decision making. [PDF]

Br J Clin Pharmacol
Kauppila M, Backman JT, Lapatto-Reiniluoto O.   +2 more
europepmc   +1 more source

Prognostic Impact of European LeukemiaNet Genetic Risk Stratification System in Adult Patients With Acute Myeloid Leukemia

Aging and Cancer, EarlyView.
This study aimed to evaluate the prognostic value of ELN2017 in predicting survival outcomes and to assess the impact of clinical and molecular factors such as age, FLT3 and NPM1 mutations, and allogeneic hematopoietic stem cell transplantation (allo‐HSCT).
Mobina Shrestha, Bishwas Mandal, Vishal Mandal, Asis Shrestha, Amir Babu Shrestha   +4 more
wiley   +1 more source

Clinical Decision-Making Case: Pediatric Sexually Transmitted Infections and Consent. [PDF]

J Educ Teach Emerg Med
Drone E, Shedd A, Rodriguez L, Patel C.
europepmc   +1 more source

Re‐Awakening Public Attention to the Silent Pandemic of Cancer Among Older Adults in Low‐ and Middle‐Income Countries

Aging and Cancer, EarlyView.
ABSTRACT As global populations age, cancer is increasingly becoming a leading cause of morbidity and mortality among older adults, particularly in low‐ and middle‐income countries (LMICs). Despite accounting for the majority of new cancer cases and deaths, older individuals remain underrepresented in cancer research, clinical guidelines, and health ...
Ibrahim Bidemi Abdullateef, Sunkanmi Folorunsho, Abdulazeez Opeyemi Abdulganiyu   +2 more
wiley   +1 more source

Impact of Large Language Model-assisted Differential Diagnosis on Clinical Decision-making in Dermatology: A Feasibility Study Using ChatGPT-5. [PDF]

Acta Derm Venereol
Yamamura Y, Fujii K, Nakashima C, Otsuka A.   +3 more
europepmc   +1 more source

Minimally Invasive Bone Regeneration in Implant Dentistry: From Biological Principles to Indication-Driven Clinical Decision-Making-A Narrative Review. [PDF]

J Clin Med
Porczyk P, Górski B.
europepmc   +1 more source

Artificial Intelligence Technologies Supporting Nurses' Clinical Decision-Making: A Systematic Review. [PDF]

J Clin Nurs
Mikkonen K, Tuunainen S, Oikarinen A, Jansson M, Woo B, Zhou W, Tam W, Tuomikoski AM, Kaakinen P, Juntunen J, Jarva E.   +10 more
europepmc   +1 more source