Results 101 to 110 of about 1,803,951 (318)

Development of a Clinical Decision Support System for Evidence-Based Management of Hypertension in Older Patients Using a No-code Platform

open access: yesИнновационная медицина Кубани
Hypertension is common among older people and often accompanied by frailty. Physicians are in need of comprehensive assessment tools to effectively manage hypertension in older patients.We conducted a literature search and evaluated current studies ...
Venera Zh. Kudabaeva   +4 more
doaj   +1 more source

Mapping the rules: conceptual and logical relationships in a system for pediatric clinical decision support [PDF]

open access: yes, 2013
The Child Health Improvement through Computer Automation (CHICA) system uses evidence-based guidelines and information collected in the clinic and stored in an electronic medical record (EMR) to inform physician and patient decision making.
Liu, Gilbert C.   +3 more
core   +1 more source

Hematopoietic (stem) cells—The elixir of life?

open access: yesFEBS Letters, EarlyView.
The aging of HSCs (hematopoietic stem cells) and the blood system leads to the decline of other organs. Rejuvenating aged HSCs improves the function of the blood system, slowing the aging of the heart, kidney, brain, and liver, and the occurrence of age‐related diseases.
Emilie L. Cerezo   +4 more
wiley   +1 more source

Impact of a Clinical Decision Support System on the Change over Time in the Anticholinergic Load in Geriatric Patients: The SADP-Antichol Study

open access: yesPharmacy
Purpose: Anticholinergic drugs can cause adverse events (AEs) in older adults. Clinical decision support systems (CDSSs) can detect prescriptions with a high anticholinergic load. Our starting hypothesis was that the anticholinergic load could be reduced
Grégoire Delvallée   +4 more
doaj   +1 more source

Falls and delirium in older inpatients: Work-as-imagined, work-as-done and preferences for clinical decision support systems

open access: hybrid, 2021
Birgit A. Damoiseaux‐Volman   +5 more
openalex   +1 more source

Medical Data Architecture Prototype Development - Summary of Recent Work and Proposed Ideas for Upcoming Work [PDF]

open access: yes
The Medical Data Architecture (MDA) project supports the Exploration Medical Capability (ExMC) risk to minimize or reduce the risk of adverse health outcomes and decrements in performance due to in-flight medical capabilities on human exploration ...
Burian, B.   +4 more
core   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

Clinical Decision Support System Used in Spinal Disorders: Scoping Review

open access: yesJournal of Medical Internet Research
BackgroundSpinal disorders are highly prevalent worldwide with high socioeconomic costs. This cost is associated with the demand for treatment and productivity loss, prompting the exploration of technologies to improve patient ...
Zheng An Toh   +6 more
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Mechanisms of parasite‐mediated disruption of brain vessels

open access: yesFEBS Letters, EarlyView.
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira   +3 more
wiley   +1 more source

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