Results 101 to 110 of about 28,420,668 (240)

Development and Implementation of a Clinical Decision Support System to Enhance Efficiency and Accuracy in Medication Prescription Review in a Tertiary Care Hospital: A Retrospective Hospital CDSS Register Study

Journal of Multidisciplinary Healthcare
Meili Lin,1 Yi He,1 Ping He,1 Hongyan Jiang,1 Huan Luo,1 Haibin Dai,1,2 Lingyan Yu1,2 1Department of Pharmacy, Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang Province, People’s Republic of China; 2Research Center ...
Lin M, He Y, He P, Jiang H, Luo H, Dai H, Yu L   +6 more
doaj  

CONCEPT FOR A CLINICAL DECISION SUPPORT SYSTEM IN GASTROINTESTINAL ENDOSCOPY

Измерение, мониторинг, управление, контроль
Background. The article considers the problem of constructing a system for supporting medical decisionmaking for endoscopic examinations of the gastrointestinal tract based on neural network methods and video data analysis algorithms.
V.V. Khryashchev
doaj   +1 more source

Development of a Clinical Decision Support System for Evidence-Based Management of Hypertension in Older Patients Using a No-code Platform

Инновационная медицина Кубани
Hypertension is common among older people and often accompanied by frailty. Physicians are in need of comprehensive assessment tools to effectively manage hypertension in older patients.We conducted a literature search and evaluated current studies ...
Venera Zh. Kudabaeva, Almagul T. Mansharipova, Larisa V. Shulzhenko, Gleb S. Krasnov, Igor V. Pershukov   +4 more
doaj   +1 more source

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Leveraging clinical decision support system tools for childhood overweight/obesity management

BMC Medical Informatics and Decision Making
Introduction Consistent with evidence-based care for pediatric overweight (BMI between 85th to 94th percentile) and obesity (BMI ≥ 95th percentile), a clinical decision support system (CDSS) OurPractice Advisory (OPA) was designed and implemented in 18 ...
Joseph R. Wardell, Nora Shaska, Zara Ahmed, Brigid Gregg, Kanakadurga Singer, Jung Eun Lee, Emily Hirschfeld, Ashley Garrity, Susan Woolford, Karen E. Peterson, Jennifer Bragg-Gresham, Kelly Orringer, Lauren Oshman, Jonathan Gabison, Layla Mohammed, Esther Yoon, Jacob Bilhartz, Bonnie Burns, Joyce M. Lee   +18 more
doaj   +1 more source

Impact of a Clinical Decision Support System on the Change over Time in the Anticholinergic Load in Geriatric Patients: The SADP-Antichol Study

Pharmacy
Purpose: Anticholinergic drugs can cause adverse events (AEs) in older adults. Clinical decision support systems (CDSSs) can detect prescriptions with a high anticholinergic load. Our starting hypothesis was that the anticholinergic load could be reduced
Grégoire Delvallée, Lisa Mondet, Chloé Cornille, Guillaume Deschasse, Aurélie Lenglet   +4 more
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

The Effect of Clinical Decision Support System on the Success of Respirative Syncytial Virus (RSV) Prophylaxis

Gazi Medical Journal
Objective: The aim was to examine the increase in the rate of respiratory syncytial virus (RSV) prophylaxis through a clinical decision support system (CDSS) added to the hospital information management system (HIS) and to determine the rate of increase ...
Gizem Karkın Tozlu, İpek Bozkurt, Serdar Kula   +2 more
doaj   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source