Results 221 to 230 of about 935,725 (295)

Quantitative proteomic analysis reveals different characteristics of bladder cancer cells after exposure to bisphenol A

FEBS Open Bio, EarlyView.
Bisphenol A (BPA), a common chemical in plastics, exerts dual effects on bladder cancer cells: low doses promote growth and migration, while high doses suppress growth and migration. Multi‐omics and bioinformatics reveal BPA acts via MAPK and inflammatory pathways.
Shaomin Niu, Lanlan Li, Wenjuan Jia, Hanzhong Feng, Xiaoquan Yu, Youli Zhao, Fengzhi Yuan, Hui Ding, Junqiang Tian, Yong‐Xing He, Zhiping Wang   +10 more
wiley   +1 more source

Experiences, challenges and lessons while implementing a clinical decision support system in Botswana. [PDF]

Oxf Open Digit Health
Ndlovu K, Stein N, Gaopelo R, Monkge M, Moen L, Molwantwa MC.   +5 more
europepmc   +1 more source

Iron homeostasis disruption and lipid peroxidation in skeletal muscle during short‐term immobilization

FEBS Open Bio, EarlyView.
14‐day casting‐induced immobilization reduced gastrocnemius muscle mass and increased non‐heme iron and ferritin heavy chain levels. Despite iron accumulation, transferrin receptor 1 and iron regulatory protein 2 were paradoxically upregulated. Lipid peroxidation was elevated without compensatory antioxidant responses.
Haruka Yokogawa, Kazuhiko Higashida, Naoya Nakai   +2 more
wiley   +1 more source

Basic components of a rule⁃driven clinical nursing decision support system:an example of an intelligent delirium nursing clinical decision aid support system

Huli yanjiu, 2022
ZHANG Shan, CUI Wei, WU Ying
doaj  

Evaluation of a clinical decision support system for dermatology in a remote area: insights from Martinique. [PDF]

Front Med (Lausanne)
Callens A, Drame M, Dugardin J, Baubion E, Perrier A, Blaizot R, Briand N, Amazan E, Ferrati-Fidelin G, Khammouma F, Olivier N, Heleine M, Baccouche A, Helenon R, Martin A, Jacquin C, Messagier AL.   +16 more
europepmc   +1 more source

Proteasomal degradation of intracellularly expressed Amblyomin‐X limits suicide gene therapy potential in melanoma cells

FEBS Open Bio, EarlyView.
This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel, Carlos DeOcesano Pereira, Aline Ramos Maia Lobba, Melissa Regina Fessel, Ana Marisa Chudzinski‐Tavassi   +4 more
wiley   +1 more source

Glycemic Efficacy and Safety by Using Insulin Degludec and Aspart Guided by a Clinical Decision Support System in Non-Critically Ill Inpatients with Type 2 Diabetes Mellitus. [PDF]

Biosensors (Basel)
Aberer F, Hochfellner DA, Baumann PM, Höll B, Beck P, Pieber TR, Mader JK.   +6 more
europepmc   +1 more source

Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system

FEBS Open Bio, EarlyView.
An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková, Veronika Hovanová, Jiri Damborsky, Erik Sedlák   +3 more
wiley   +1 more source

Development of the ERATbi App, a Clinical Decision Support System for Early Recovery After Traumatic Brain Injury in the ICU: Usability Study. [PDF]

JMIR Hum Factors
Yen HC, Wu IH, Hsiao WL, Lai SR, Yang CH, Liao HC, Han YY.   +6 more
europepmc   +1 more source