Results 71 to 80 of about 28,418,912 (162)

Evaluating the effects of a hospital utilisation improvement program on platelet transfusions: A pre‐post study

Transfusion Medicine, EarlyView.
Abstract Background Annually millions of platelet concentrate (PC) are transfused worldwide. The decision regarding PC transfusion is often complex; therefore, the implementation of a hospital programme designed to streamline and facilitate the decision‐making process is beneficial. Such a programme helps standardise transfusion practices, ensures that
Piotr F. Czempik, Jakub Rudzki, Michał Porada   +2 more
wiley   +1 more source

Agomelatine as augmentation therapy with second‐generation antipsychotics for negative symptoms of schizophrenia: An open‐label randomised clinical trial and electroencephalogram‐derived model for treatment response prediction

General Psychiatry, Volume 39, Issue 5, October 2026.
ABSTRACT Background Negative symptoms are a core diagnostic domain of schizophrenia that affect functional outcomes and remain difficult to treat. Agomelatine, a novel antidepressant with melatonin receptor agonism and serotonin 2C receptor antagonism, may have therapeutic potential.
Wanyan Zhou, Fei Liang, Nizhe Chen, Yao Zhang, Xiaoxiao Wang, Xin Li, Daofeng Lu, Fang Guo, Yuan Yao, Jiayu Zhu, Chengjia Shen, Chongze Wang, Peiyun Zhang, Lilan Zhao, Ying Wang, Jinyu Han, Wei Li, Haisu Wu, Peijuan Wang, Qi Yan, Ping Zhang, Qinyu Lv, Zhenghui Yi   +22 more
wiley   +1 more source

Patient Information and Surgery Decisions: A Discrete Choice Experiment

Health Economics, Volume 35, Issue 10, Page 1571-1596, October 2026.
ABSTRACT Surgical treatments are offered more widely than ever before, increasingly to older and high‐risk patients. However, it is unclear whether patients making surgical decisions are fully informed about the risks of surgery and the available non‐surgical treatments.
Francesca Cornaglia, Alessandro Iaria, Eugenio Felipe Merlano, John R. Prowle   +3 more
wiley   +1 more source

Methodologies of Legacy Clinical Decision Support System

, 2017
Information technology playing a prominent role in the field of medical by incorporating the clinical decision support system (CDSS) in their routine practices.
Meenakshi Sharmi, Himanshu Aggarwal
core   +1 more source

The Construction and Application of a Clinical Decision Support System for Cardiovascular Diseases: Multimodal Data-Driven Development and Validation Study

JMIR Medical Informatics
BackgroundDue to the acceleration of the aging population and the prevalence of unhealthy lifestyles, the incidence of cardiovascular diseases (CVDs) in China continues to grow.
Shumei Miao, Pei Ji, Yongqian Zhu, Haoyu Meng, Mang Jing, Rongrong Sheng, Xiaoliang Zhang, Hailong Ding, Jianjun Guo, Wen Gao, Guanyu Yang, Yun Liu   +11 more
doaj   +1 more source

Deliver intelligence to integrate care: the Connecare way

International Journal of Integrated Care, 2019
Background: According to the European Patient Forum, patient empowerment is the process helping people gain control over their own lives, by increasing their ability to act on issues that they themselves regard as important.
Stefano Mariani, Eloisa Vargiu, Marco Mamei, Franco Zambonelli, Felip Miralles   +4 more
doaj   +1 more source

From the lethal triad to the lethal diamond and beyond: An AI‐augmented perspective on modern hemostatic resuscitation

Hong Kong Journal of Emergency Medicine, Volume 33, Issue 5, October 2026.
Abstract Background Uncontrolled hemorrhage remains the leading cause of preventable mortality in both civilian and military trauma sectors. The paradigm of resuscitation has decisively shifted from aggressive crystalloid administration to Damage Control Resuscitation, centering on early hemostatic control and the mitigation of the “Lethal Diamond ...
Jonghee Han, Junepill Seok, Su Young Yoon, Jin‐Uk Choi, Jin Suk Lee, Younghoon Sul   +5 more
wiley   +1 more source

MicroRNA–mRNA Networks in Skeletal Muscle of Tailored Pig Models for Dystrophinopathies

Journal of Cachexia, Sarcopenia and Muscle, Volume 17, Issue 5, October 2026.
ABSTRACT Background Duchenne muscular dystrophy (DMD) and Becker muscular dystrophy (BMD) are X‐linked dystrophinopathies caused by mutations in the dystrophin (DMD) gene. A common DMD‐causing mutation in humans is exon 52 deletion (DMDΔ52), which disrupts the reading frame and abolishes dystrophin expression.
Sarah Reschke, Alexander Graf, Frieder Hadlich, Florian Jaudas, Thomas Fröhlich, Michael Stirm, Nikolai Klymiuk, Stefan Krebs, Eckhard Wolf, Asghar Ali   +9 more
wiley   +1 more source

Combining alcohol interventions with tobacco addictions treatment in primary care—the COMBAT study: a pragmatic cluster randomized trial

Implementation Science, 2017
Background Tobacco and alcohol use present multiplicative risk for aerodigestive cancers. Reducing alcohol consumption improves smoking cessation outcomes and reduces cancer risk. Risky alcohol consumption and smoking are often treated separately despite
Nadia Minian, Dolly Baliunas, Laurie Zawertailo, Aliya Noormohamed, Norman Giesbrecht, Christian S. Hendershot, Bernard Le Foll, Jürgen Rehm, Andriy Samokhvalov, Peter L. Selby   +9 more
doaj   +1 more source

A Post–NGP Mitsuokella jalaludinii as a Therapeutic Candidate for Gout

MicrobiologyOpen, Volume 15, Issue 5, October 2026.
Schematic summary of the therapeutic mechanisms and evaluation of the post–NGP strain M. jalaludinii PMC73 for gout. PMC73 demonstrated uric acid–lowering efficacy through purine catabolism and hypoxanthine utilization, along with intracellular uric acid reduction in macrophages.
Mohammed Solayman Hossain, Sukyung Kim, Md Tareque Aziz, Izaz Ahmed, Md Sarower Hossen Shuvo, Hyewon Yang, Yunjeong Jang, Minseo Kim, Seohyeon Jang, Yusol Kim, Soeun Oh, Yunseo Nam, Hoonhee Seo, Ho‐Yeon Song   +13 more
wiley   +1 more source