Results 41 to 50 of about 1,329,296 (288)

Dexamethasone for Chemotherapy‐Induced Nausea and Vomiting Prevention in Pediatric Patients: International Consensus

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background An international Delphi panel of experts developed consensus statements to delineate the circumstances where the risks of dexamethasone as an antiemetic do and do not outweigh its benefits. Procedure Experts in supportive care of pediatric patients were invited to participate.
Negar Shavandi, Paula D. Robinson, Shana Jacobs, L. Lee Dupuis, the International Pediatric Dexamethasone Panel, Sameer Bakhshi, Tiene Bauters, Eva Brack, Simone Cesaro, Claire Fosbrook, Jason Freedman, Tamara MacDonald, Eloise Neumann, Venkatraman Radhakrishnan, Rod Rassekh, Florian Slimano, Johnathan Soggee, Joel Thompson, Marianne van de Wetering, Milena Villarroel, Jasper Wong   +20 more
wiley   +1 more source

Clinical Insights Into Hypercalcemia of Malignancy in Childhood

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Hypercalcemia of malignancy (HCM) is a rare but life‐threatening metabolic emergency in children that occurs in less than 1% of pediatric cancer cases, with a reported incidence ranging from 0.4% to 1.0% across different studies. While it is observed in 10%–20% of adult malignancies, pediatric HCM remains relatively uncommon.
Hüseyin Anıl Korkmaz
wiley   +1 more source

Modelling clinical narrative as computable knowledge: The NICE computable implementation guidance project

Learning Health Systems, 2023
Introduction Translating narrative clinical guidelines to computable knowledge is a long‐standing challenge that has seen a diverse range of approaches.
Philip Scott, Michaela Heigl, Charles McCay, Polly Shepperdson, Elia Lima‐Walton, Elisavet Andrikopoulou, Klara Brunnhuber, Gary Cornelius, Susan Faulding, Ben McAlister, Shaun Rowark, Matthew South, Mark R. Thomas, Justin Whatling, John Williams, Jeremy C. Wyatt, Felix Greaves   +16 more
doaj   +1 more source

The three numbers you need to know about healthcare: the 60-30-10 Challenge [PDF]

, 2020
BACKGROUND: Healthcare represents a paradox. While change is everywhere, performance has flatlined: 60% of care on average is in line with evidence- or consensus-based guidelines, 30% is some form of waste or of low value, and 10% is harm.
Braithwaite, Jeffrey, Glasziou, Paul, Westbrook, Johanna   +2 more
core   +1 more source

Survival Outcomes and Complications Among Canadian Children With Retinoblastoma: A Population‐Based Report From CYP‐C

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Purpose Retinoblastoma (RB) is the most common pediatric ocular cancer, yet population‐based data on survival and risk factors remain limited. This study aimed to describe survival in a large national RB cohort and identify predictors of death and complications.
Samuel Sassine, Ofélie Trudeau‐Ferrin, Caroline Laverdière, Patrick Hamel, Rosanne Superstein, Bénédicte Koukoui, Carole Provost, Paul C. Nathan, Vijay Ramaswamy, Furqan Shaikh, Brenda Gallie, Ashwin Mallipatna, Stephanie Kletke, Helen Dimaras, Hallie Coltin   +14 more
wiley   +1 more source

Personalized Selumetinib Dosing in Pediatric Neurofibromatosis Type 1: Insights From a Pilot Therapeutic Drug Monitoring Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Objective To evaluate selumetinib exposure using therapeutic drug monitoring (TDM) in pediatric patients with neurofibromatosis type 1 (NF1) and plexiform neurofibromas (PN), assess interpatient pharmacokinetic variability, and explore the relationship between drug exposure, clinical response, and adverse effects.
Janka Kovács, Zoltán Köllő, Balázs Gellért Karvaly, Mahmoud Obeidat, Rita Nagy, Péter Hegyi, Brigitta Teutsch, Eszter Tuboly, Miklós Garami   +8 more
wiley   +1 more source

Automated quality control for proton magnetic resonance spectroscopy data using convex non-negative matrix factorization [PDF]

, 2016
Proton Magnetic Resonance Spectroscopy (1H MRS) has proven its diagnostic potential in a variety of conditions. However, MRS is not yet widely used in clinical routine because of the lack of experts on its diagnostic interpretation.
Arús, Carles, Julià Sapé, Margarida, Kyathanahally, Sreenath P., Mocioiu, Victor, Vellido Alcacena, Alfredo   +4 more
core   +1 more source

Mobile phone apps for clinical decision support in pregnancy: a scoping review

BMC Medical Informatics and Decision Making, 2019
Background The use of digital technology in healthcare has been found to be useful for data collection, provision of health information and communications.
Jenny Carter, Jane Sandall, Andrew H. Shennan, Rachel M. Tribe   +3 more
doaj   +1 more source

Applications of Clinical Decision Support Systems in Diabetes Care: Scoping Review

Journal of Medical Internet Research, 2023
BackgroundProviding comprehensive and individualized diabetes care remains a significant challenge in the face of the increasing complexity of diabetes management and a lack of specialized endocrinologists to support diabetes care.
Shan Huang, Yuzhen Liang, Jiarui Li, Xuejun Li   +3 more
doaj   +1 more source

Automated recognition and post-coordination of complex clinical terms [PDF]

, 2011
One of the key tasks in integrating guideline-based decision support systems with the electronic patient record is the mapping of clinical terms contained in both guidelines and patient notes to a common, controlled terminology.
Gooch, P., Roudsari, A.
core