Results 1 to 10 of about 10,615,218 (316)

Hyperglycemia induces PFKFB3 overexpression and promotes malignant phenotype of breast cancer through RAS/MAPK activation

open access: yesWorld Journal of Surgical Oncology, 2023
Background Breast cancer is the most common tumor in women worldwide. Diabetes mellitus is a global chronic metabolic disease with increasing incidence. Diabetes mellitus has been reported to positively regulate the development of many tumors.
Xiao Cheng   +6 more
doaj   +1 more source

Effect of antibiotic prophylaxis in the prognosis of Post-neurosurgical meningitis patients

open access: yesEuropean Journal of Medical Research, 2023
Aims To evaluate the effect of antibiotic prophylaxis(AP) in the prognosis of Post-neurosurgical meningitis(PNM) patients. Methods A cohort analysis was performed using the clinical database in Beijing Tiantan Hospital and Capital Medical University ...
Guanghui Zheng   +6 more
doaj   +1 more source

Case Report: Clinicopathological characteristics of patients with gastric cancer with features of a submucosal tumour

open access: yesFrontiers in Oncology, 2023
PurposeTo investigate the clinicopathological characteristics, diagnosis and key points in the differential diagnosis of patients with gastric cancer (GC) with features of a submucosal tumour (GCSMT).MethodsThe clinical presentation and imaging findings ...
Chunnian Wang   +5 more
doaj   +1 more source

Phenotype, molecular characterisation and risk factors for postoperative meningitis caused by ESBL-producing-Enterobacteriaceae: a six years multi-Centre comparative cohort study

open access: yesBMC Infectious Diseases, 2021
Background To determine the phenotype, molecular characterisation and risk factors of postoperative meningitis induced by Extended-spectrum β-lactamase (ESBL)-producing Enterobacteriaceae (EPE) in China.
Guanghui Zheng   +10 more
doaj   +1 more source

Circular RNA UBAP2 contributes to tumor growth and metastasis of cervical cancer via modulating miR-361-3p/SOX4 axis

open access: yesCancer Cell International, 2020
Background Increasing researches have reported that circular RNA UBAP2 (circUBAP2) may be a potential prognosis biomarker and participate in the development of several cancers; however, the role of circUBAP2 in cervical cancer (CC) remains largely ...
Lingli Meng   +5 more
doaj   +1 more source

Primary Xp11 translocation PEComa of the testis with SFPQ⁃TFE3 rearrangement: a case report and review of the literature

open access: yesDiagnostic Pathology, 2023
Background Perivascular epithelioid cell neoplasms (PEComas) are a family of mesenchymal tumors with features of both smooth muscle and melanocytic differentiation. A subset of PEComas demonstrate rearrangements involving the TFE3 (Xp11) locus.
Huizhi Zhang, Suying Wang, Lingli Meng
doaj   +1 more source

Translation: Expert Consensus on the Application of Artificial Liver Blood Purification System in the Treatment of Severe and Critical COVID-19

open access: yesInfectious Microbes & Diseases, 2020
. The prevention and treatment of COVID-19 nationwide has entered a tackling phase. Effective treatment of severe and critically ill patients is the key to reducing the fatality of the disease.
National Clinical Research Center for Infectious Diseases, State Key Laboratory for Diagnosis and Treatment of Infectious Diseases⊠ van der Veen
doaj   +1 more source

Case report: Meningioma associated with meningioangiomatosis mimicking invasive meningioma

open access: yesFrontiers in Neurology, 2023
Meningioangiomatosis (MA) is a rare malformation or hamartomatous lesion in the central nervous system, characterized by a plaque-like mass within the leptomeninges and cerebral cortex. An even rarer condition is MA complicated with meningiomas.
Rong Ge   +3 more
doaj   +1 more source

Next-generation sequencing for D47N mutation in Cx50 analysis associated with autosomal dominant congenital cataract in a six-generation Chinese family

open access: yesBMC Ophthalmology, 2017
Background Congenital cataract is the most frequent cause of blindness during infancy or early childhood. To date, more than 40 loci associated with congenital cataract have been identified, including at least 26 genes on different chromosomes associated
Chao Shen   +9 more
doaj   +1 more source

Single-cell transcriptomics provide insight into metastasis-related subsets of breast cancer

open access: yesBreast Cancer Research, 2023
Breast cancer metastasis is a complex, multi-step process, with high cellular heterogeneity between primary and metastatic breast cancer, and more complex interactions between metastatic cancer cells and other cells in the tumor microenvironment.
Shikun Zhu   +7 more
doaj   +1 more source

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