Results 21 to 30 of about 928,675 (261)

Clinical Parameters to Predict Future Clinical Disease Activity After Treatment Change to Higher-Dose Subcutaneous Interferon Beta-1a From Other Platform Injectables in Patients With Relapsing-Remitting Multiple Sclerosis

Frontiers in Neurology, 2020
Objective: To identify predictors of clinical disease activity after treatment change to higher-dose interferon beta-1a in relapsing-remitting multiple sclerosis (MS).Methods: This was a retrospective-prospective observational multicenter study.
Martina Novotna, Ales Tvaroh, Ales Tvaroh, Jan Mares   +3 more
doaj   +1 more source

Tight control of rheumatoid arthritis in a resource-constrained setting: a randomized controlled study comparing the clinical disease activity index and simplified disease activity index [PDF]

Rheumatology, 2014
The aim of this study was to explore the clinical utility of the clinical disease activity index (CDAI). We compared the disease control with protocolized treatment adjustment following a tight control strategy utilizing either the simplified disease activity index (SDAI) or the CDAI.In a prospective 12 month study, DMARD-naive RA patients were ...
Bridget, Hodkinson, Eustatius, Musenge, Mohammed, Tikly   +2 more
openaire   +2 more sources

Patients’ and clinicians’ perspectives on the clinical utility of the Rheumatoid Arthritis Foot Disease Activity Index

Rheumatology International, 2022
AbstractAlthough patient-reported outcome measures (PROMs) are recommended in clinical practice, their application in routine care is limited. The Rheumatoid Arthritis Foot Disease Activity Index (RADAI-F5) is a validated PROM for assessing foot disease in rheumatoid arthritis (RA).
Anika Hoque, Martijn Steultjens, Diane M. Dickson, Gordon J. Hendry   +3 more
openaire   +3 more sources

Histamine index and clinical expression of rheumatoid arthritis activity [PDF]

Vojnosanitetski Pregled, 2010
Background/Aim. Many arguments prove the pathophysiologic role of histamine in the process of remodeling and joint destruction in rheumatoid arthritis.
Tomić-Lučić Aleksandra P., Pantović Suzana B., Rosić Gvozden L., Obradović Zdravko M., Rosić Mirko A.   +4 more
doaj   +1 more source

Sjogren's Systemic Clinical Activity Index (SCAI) a systemic disease activity measure for use in clinical trials in primary Sjogren's syndrome [PDF]

Rheumatology, 2007
This article describes the development of the Sjögren's Systemic Clinical Activity Index (SCAI) for the measurement of systemic disease activity in patients with primary Sjögren's syndrome (PSS).A pilot tool was developed based on expert consensus and previous published data.
S J, Bowman, N, Sutcliffe, D A, Isenberg, F, Goldblatt, M, Adler, E, Price, A, Canavan, J, Hamburger, A, Richards, S, Rauz, M, Regan, K, Gadsby, S, Rigby, A, Jones, R, Mathew, D, Mulherin, A, Stevenson, P, Nightingale   +17 more
openaire   +2 more sources

Correlation of rheumatoid arthritis activity indexes (Disease Activity Score 28 measured with ESR and CRP, Simplified Disease Activity Index and Clinical Disease Activity Index) and agreement of disease activity states with various cut-off points in a Northeastern Brazilian population

Revista Brasileira de Reumatologia (English Edition), 2015
The Disease Activity Score 28 (DAS28) and its versions have been used to measure rheumatoid arthritis (RA) activity, but there is no consensus about which one is the best.Determine the correlation among indexes (DAS28 ESR, DAS28 CRP, SDAI and CDAI) and evaluate agreement of activity strata using different cutoff points.Rheumatoid arthritis patients ...
Medeiros, Marta Maria das Chagas, Oliveira, Brenda Maria Gurgel Barreto de, Cerqueira, João Victor Medeiros de, Quixadá, Raquel Telles de Souza, Oliveira, Ídila Mont’Alverne Xavier de   +4 more
openaire   +2 more sources

Bridging the Loneliness Gap: Depression, Connectivity, and Isolation in Pediatric Oncology Patients and Their Peers

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Loneliness is associated with adverse physical and mental health outcomes and remains understudied in children and adolescents undergoing cancer therapy. Pediatric oncology patients may be at increased risk due to medical isolation and disruption of social networks.
Charlotte N. Stahlfeld, Scott H. Maurer, Michelle D. Watkinson, John Nury, Elise Barberis, Molly C. Mack   +5 more
wiley   +1 more source

Comparative Drug Response Profiling in Neuroblastoma Cell Lines and Patient‐Derived Tumor Organoids

Pediatric Blood &Cancer, EarlyView.
ABSTRACT High‐risk neuroblastoma remains a leading cause of pediatric cancer mortality, and improved preclinical models are needed to guide therapeutic developments. We screened seven high‐risk neuroblastoma cell lines and three patient‐derived tumor organoids with 528 compounds alongside bone marrow controls, and compared them with external datasets ...
Krzysztof Wierbiłowicz, Se Whee Sammy Park, Aironas Los, Ernest Liu, Nona Struyf, Tom Erkers, Sören Lehmann, Jan J. Molenaar, Jakob Stenman, Olli Kallioniemi, Päivi Östling, Brinton Seashore‐Ludlow, Kasper Karlsson   +12 more
wiley   +1 more source

Prognostic evaluation of early rheumatoid arthritis

Swiss Medical Weekly, 2010
The progression of rheumatoid arthritis (RA) is quite variable, ranging from very mild or subclinical forms (approx. 10%) to rapidly progressing and debilitating forms (10–15%).
Mota da, IM Laurindo, Carvalho de, Santos-Neto dos   +3 more
doaj   +1 more source

Impact of Radiation Therapy on Physical and Psychosocial Health of Adolescents and Young Adults: A Joint Report From the Children's Oncology Group AYA and Radiation Oncology Committees

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Rates of cancer among adolescents and young adults (AYA), age 15–39 years, are increasing. Consequently, radiation oncologists are treating more AYAs who have diagnoses spanning both pediatric and adult practices. Compared to pediatric and older adult patients, AYAs face a unique set of challenges.
Hesham Elhalawani, Rachel K. Peterson, Avani D. Rao, Laurie J. McKenzie, Ahmed Magdy Elmotayam, Leslie Chang, Michael Roth, Susan L. McGovern   +7 more
wiley   +1 more source