Results 71 to 80 of about 9,396,953 (279)

Recent progress in gene therapy for familial hypercholesterolemia treatment

iScience
Summary: Familial hypercholesterolemia (FH) is a genetic disorder that affects 1 in 300 people, leading to high cholesterol levels and significantly increased cardiovascular risk.
Yaxin Luo, Yaofeng Hou, Wenwen Zhao, Bei Yang   +3 more
doaj   +1 more source

The making of an endocrinologist in India: Life and times at Institute of Post Graduate Medical Education and Research Calcutta

Indian Journal of Endocrinology and Metabolism, 2015
Endocrinology is relatively one of the newer super-specialties of internal medicine. Following higher secondary schooling, it takes anywhere between 13 and 18 years to become a super-specialist in India, which holds true for endocrinology also.
Deep Dutta
doaj   +1 more source

Clinical signs and behavior in dogs with hypothyroidism

Macedonian Veterinary Review, 2023
This descriptive study aims to examine the behavior of dogs diagnosed with hypothyroidism and the potential effect of hormonal treatment. Eight client-owned dogs with clinical hypothyroidism were evaluated using an adapted C-BARQ questionnaire, clinical ...
Elena Mitrevska, Irena Celeska, Miroslav Kjosevski, Elena Atanaskova Petrov   +3 more
doaj   +1 more source

Redox‐Responsive Tellurium‐Bridged Covalent Organic Frameworks/PEG Composites for Targeted Therapy of Diabetic Cardiomyopathy

Advanced Science, EarlyView.
This study unlocks the immense potential of COF@polymer nanocomposites as a multifunctional therapeutic platform for targeted drug delivery in diabetic cardiomyopathy. Abstract Diabetic cardiomyopathy, a major complication of diabetes, is strongly associated with elevated levels of glycated hemoglobin (HbA1c) and reactive oxygen species (ROS). However,
Jing Xue, Jialu Zhuang, Taotao Fan, Songtao Tang, Junjun Wang, Xiaohui Liu, Jian Liu, Jin Shi, Jiaji Li, Wanjun Li, Danyou Hu, Xiaoqian Zhang, Hua Wang, Guiyang Zhang   +13 more
wiley   +1 more source

Request of endocrinology and metabolism journals for data sharing statements in clinical trial reports: a survey

Frontiers in Medicine
BackgroundTo enhance reproducibility and transparency, the International Committee of Medical Journal Editors (ICMJE) required that all trial reports submitted after July 2018 must include a data sharing statement (DSS).
Yingxin Liu, Bo Chen, Jingyi Zhang, Xuerui Bai, Lili Kang, Wenli Li, Guowei Li, Guowei Li, Guowei Li   +8 more
doaj   +1 more source

Experiencia con el proyecto ENDMAP, una actividad formativa para médicos de familia en endocrinología y nutrición

Atención Primaria Práctica, 2023
Resumen: Es sabido que la atención primaria (AP) en España está sometida a un importante estrés debido al gran volumen asistencial que soporta. El envejecimiento de la población, el incremento de las enfermedades crónicas, como la diabetes y los factores
Agustín Ángel Merchante Alfaro, Concha F. García-Prieto, Diana Riba Artés, Diego Bellido Guerrero   +3 more
doaj   +1 more source

AMERICAN ASSOCIATION OF CLINICAL ENDOCRINOLOGISTS AND AMERICAN COLLEGE OF ENDOCRINOLOGY GUIDELINES FOR MANAGEMENT OF GROWTH HORMONE DEFICIENCY IN ADULTS AND PATIENTS TRANSITIONING FROM PEDIATRIC TO ADULT CARE.

Endocrine Practice, 2019
Objective: The development of these guidelines is sponsored by the American Association of Clinical Endocrinologists (AACE) Board of Directors and American College of Endocrinology (ACE) Board of Trustees and adheres with published AACE protocols for the
K. Yuen, B. Biller, S. Radovick, J. Carmichael, Sina Jasim, K. Pantalone, A. Hoffman   +6 more
semanticscholar   +1 more source

Combination GLP-1 and Insulin Treatment Fails to Alter Myocardial Fuel Selection Versus Insulin Alone in Type 2 Diabetes [PDF]

, 2018
Context Glucagon-like peptide-1 (GLP-1) and the clinically available GLP-1 agonists have been shown to exert effects on the heart. It is unclear whether these effects occur at clinically used doses in vivo in humans, possibly contributing to CVD risk ...
Considine, Robert V., Goodwill, Adam, Green, Mark A., Hamilton, LaTonya, Hutchins, Gary D., Mather, Kieren J., Mathias, Carla, Patel, Niral A., Territo, Wendy, Tune, Johnathan D.   +9 more
core   +1 more source

Decoding Human Placental Cellular and Molecular Responses to Obesity and Fetal Growth

Advanced Science, EarlyView.
Women with obesity often deliver large‐for‐gestational‐age (LGA) infants. Single‐nucleus RNA sequencing of term placenta reveals that hypoxia and TNF‐α signaling in syncytiotrophoblasts are featured in maternal obesity, but inflammatory signatures in Hofbauer cells and response to lipid or carbohydrate metabolism in fibroblasts are specific to LGA.
Hong Jiang, Emilie Derisoud, Denise Parreira, Nayere Taebnia, Paulo R. Jannig, Reza Zandi Shafagh, Allan Zhao, Congru Li, Macarena Ortiz, Manuel Alejandro Maliqueo, Elisabet Stener‐Victorin, Volker M. Lauschke, Qiaolin Deng   +12 more
wiley   +1 more source

The thyroid eye disease (TED) laterality debate: A comparison of characteristics, presentation, severity, and activity, between unilateral and bilateral thyroid eye disease

Clinical Epidemiology and Global Health, 2022
Background/objectives: Thyroid eye disease (TED), which can lead to severe sequelae, can involve either one eye or both eyes. The importance of knowing the distinction between laterality rests on the risk that either presentation is associated with a ...
Ronald Steven S. Medalle II, MD, MBA, Red Thaddeus D. Miguel, MD, MBA   +1 more
doaj   +1 more source