Results 51 to 60 of about 169,755 (257)

Ethics Committees for "High Tech" Innovations in Japan

open access: yes, 1989
Although ethics committees in Japan have been developing in major medical schools and in some hospitals, their members are usually medical professionals from the same institution. The lack of national legislation for setting up ethics committees permits
Kimura, Rihito
core   +1 more source

Serum Myonectin Levels Are Positively Associated With Physical Function and Lower Frailty‐Related Limitation in Maintenance Hemodialysis Patients: A Cross‐Sectional Study

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Maintenance hemodialysis (MHD) patients frequently suffer from frailty, characterized by reduced physical function and poor prognosis. Myokines, such as myonectin, secreted by muscle, are emerging regulators of systemic health. This study investigated the relationship between serum myonectin, adipokines (adiponectin, omentin), and ...
Kenichi Kono   +7 more
wiley   +1 more source

Evaluation of clinical trials by Ethics Committees in Germany: Experience of applicants with the review of requests for opinion of the Ethics Committees - results of a survey among members of the German Association of Research-Based Pharmaceutical Companies (VFA)

open access: yesGMS German Medical Science, 2009
The review of requests for a positive opinion of the ethics committees (application procedure) as a requirement to start a clinical trial in Germany has been completely redesigned with the transposition of EU Directive 2001/20/EC in the 12th Amendment of
Russ, Hagen   +4 more
doaj  

Clinical ethics support services in the UK : an investigation of the current provision of ethics support to health professionals in the UK

open access: yes, 2001
OBJECTIVE: To identify and describe the current state of clinical ethics support services in the UK. DESIGN: A series of questionnaire surveys of key individuals in National Health Service (NHS) trusts, health authorities, health boards, local ...
Bunch, C   +5 more
core   +1 more source

The role of patients in European clinical ethics consultation [PDF]

open access: yes, 2009
Clinical ethics committees and consultation services have existed in many European countries for over two decades. Many different modes of operation have emerged, each reflecting a particular health and socio-political context.
Newson, Ainsley J   +7 more
core   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

open access: yesFEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi   +5 more
wiley   +1 more source

A Review on Clinical Ethics Committees and Clinical Ethics Consultation

open access: yes, 2021
Hospital Ethics Committees (HECs) are developing a stronger presence of clinical ethics in the hospital through more proactive and efficient clinical consultation ...
Sotomayor, Claudia R.
core  

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Ensaios clínicos. Algumas questões éticas gerais.

open access: yesActa Médica Portuguesa, 1999
This article provides an overview of the main problems that ethics committees deal with when analysing clinical trials. Some characteristics of the different phases are discussed as well as some particular problems of the Portuguese law.
J A Melo
doaj   +1 more source

Impact of recent legislative bills regarding clinical research on Italian ethics committee activity.

open access: yes, 2008
: Aims and background: The present work assessed the impact of two decrees on ethics committees in Italy, aimed at bringing the national laws on the conduct of clinical trials into line with the rest of the EC, and regulating and facilitating not-for ...
POLI D   +10 more
core   +1 more source

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