Results 61 to 70 of about 6,210,863 (296)
Empirical assessments of clinical ethics services: implications for clinical ethics committees [PDF]
Clinical Ethics, 2007 The need to evaluate the performance of clinical ethics services is widely acknowledged although work in this area is more developed in the United States. In the USA many studies that assess clinical ethics services have utilized empirical methods and assessment criteria.
openaire +3 more sources
A Review on Clinical Ethics Committees and Clinical Ethics Consultation
, 2021 Hospital Ethics Committees (HECs) are developing a stronger presence of clinical ethics in the hospital through more proactive and efficient clinical consultation ...
Sotomayor, Claudia R.
core
FEBS Letters, EarlyView.Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi +5 more
wiley +1 more source
Clinical ethics and the role of clinical ethics committees: proposals for a revival. Commentary.
Annali dell'Istituto superiore di sanita, 2018 The issue addressed in the paper published by the Italian National Bioethics Committee (NBC) entitled "Clinical ethics committees", is highly significant for many reasons. One of these is the fact that the ethics committees charged with assessing clinical trials have so much responsibility and such a heavy work-load that they have little time available
Carlo Petrini, Walter Ricciardi
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, 2001 OBJECTIVE: To identify and describe the current state of clinical ethics support services in the UK. DESIGN: A series of questionnaire surveys of key individuals in National Health Service (NHS) trusts, health authorities, health boards, local ...
Bunch, C +5 more
core +1 more source
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
FEBS Letters, EarlyView.Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
Ensaios clínicos. Algumas questões éticas gerais.
Acta Médica Portuguesa, 1999 This article provides an overview of the main problems that ethics committees deal with when analysing clinical trials. Some characteristics of the different phases are discussed as well as some particular problems of the Portuguese law.
J A Melo
doaj +1 more source
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
FEBS Letters, EarlyView.GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
The structure and function of research ethics committees in Africa: A case study [PDF]
, 2007 Mokhachane, M +12 more
core +6 more sources