Results 11 to 20 of about 2,881,753 (249)

Clinical Characteristics of the Premature Ejaculation Sufferers in Aegean Region of the Turkey: A Multicentre, Observational Study

Journal of Urological Surgery, 2014
Demonstration of the intra-vaginal ejaculation latency time (IELT) distribution in male subjects and its clinical expressions among couples in the Aegean region of the Turkey.
Ahmet Cihan, Ömer Demir, Ali Şahin, Fatih Zeren, Deniz Bolat, Burak Özçift, Abdulkadir Pektaş, Ertan Can, Bilal Gümüş, Tahir Turan, Ahmet Bölükbaşı, Haluk Erol, Ahmet Adil Esen   +12 more
doaj   +1 more source

A poly(dimethylsiloxane)-based solid-phase microchip platform for dual detection of Pseudorabies virus gD and gE antibodies

Frontiers in Cellular and Infection Microbiology, 2022
Pseudorabies caused by pseudorabies virus (PRV) infection is still a major disease affecting the pig industry; its eradication depends on effective vaccination and antibody (Ab) detection.
Jiaojiao Pan, Yufang Li, Tongyan Wang, Jingfeng Chang, Liying Hao, Junjie Chen, Wuping Peng, Junhua Deng, Baicheng Huang, Kegong Tian   +9 more
doaj   +1 more source

Evaluation of Individuals with Non-Syndromic Global Developmental Delay and Intellectual Disability

Children, 2023
Global Developmental Delay (GDD) and Intellectual Disability (ID) are two of the most common presentations encountered by physicians taking care of children.
Rowim AlMutiri, Maisa Malta, Michael I. Shevell, Myriam Srour   +3 more
doaj   +1 more source

Por que os portadores de cardiomiopatia chagásica têm pior evolução que os não-chagásicos? Why do patients with chagasic cardiomyopathy have worse outcomes than those with non-chagasic cardiomyopathy?

Arquivos Brasileiros de Cardiologia, 2008
FUNDAMENTO: A insuficiência cardíaca é uma doença de alta prevalência, com prognóstico dependente de diferentes fatores preditores. OBJETIVO: A doença de Chagas é um preditor de mau prognóstico em pacientes com insuficiência cardíaca (IC) crônica.
Christiano Pereira Silva, Carlo Henrique Del Carlo, Mucio Tavares de Oliveira Junior, Airton Scipioni, Celia Strunz-Cassaro, José Antonio Franchini Ramirez, Antonio Carlos Pereira Barretto   +6 more
doaj   +1 more source

LC–MS/MS Method for Measurement of Thiopurine Nucleotides (TN) in Erythrocytes and Association of TN Concentrations With TPMT Enzyme Activity

Frontiers in Pharmacology, 2022
Monitoring concentrations of thiopurine metabolites is used clinically to prevent adverse effects in patients on thiopurine drug therapy. We developed a LC–MS/MS method for the quantification of 6-thioguanine (6-TG) and 6-methylmercaptopurine (6-MMP) in ...
Amol O. Bajaj, Mark M. Kushnir, Mark M. Kushnir, Erik Kish-Trier, Rachel N. Law, Lauren M. Zuromski, Alejandro R. Molinelli, Gwendolyn A. McMillin, Gwendolyn A. McMillin, Kamisha L. Johnson-Davis, Kamisha L. Johnson-Davis   +10 more
doaj   +1 more source

Impact of the FDA roadmap and perspectives for regulatory use of new approach methodologies in Japanese pharmaceutical companies

NAM Journal
Pharmaceutical scientists develop and apply increasingly complex technologies from an expanding toolbox to create more effective and safer drugs.
Tetsuro Araki, Hitoshi Naraoka, Yuta Asakawa, Toru Usui, Dai Kakiuchi, Seiichiro Kurashige, Tadahiro Shinozawa, Kimika Nakamura, Takumi Noda, Satomi Nishikawa, Mutsumi Suzuki   +10 more
doaj   +1 more source

Role of clinical evaluation in the identification of coronary obstructive disorders in patients with stable coronary artery disease. Part I

Российский кардиологический журнал, 2019
To make a decision on choice the type of myocardial revascularization in patients with coronary artery disease (CAD), an invasive coronary angiography (CAG) is necessary. However, in clinical practice, a significant number of patients during CAG fails to
A. N. Sumin
doaj   +1 more source

The Measure of an Outcome: Comparing Norming and Stacking to Benchmark the Effectiveness of Brain Injury Rehabilitation Services

Behavioral Sciences, 2023
Practitioners have a clinical, ethical, academic, and economic responsibility to dispassionately consider how effective their services are. Approaches to measure how “good” or “bad” healthcare is include clinical audit, satisfaction surveys, and routine ...
Sara D. S. Ramos, Rudi Coetzer
doaj   +1 more source

Accelerating Shigella vaccines: from decades of research to global access

Expert Review of Vaccines
Introduction Shigella remains one of the leading causes of severe pediatric diarrheal deaths, especially in low- and middle-income countries. Despite more than a century of sustained research efforts, there is no globally licensed Shigella vaccine.Areas ...
Shiferaw Tesfaye Tilahun, Sun Bean Kim, Naveena Aloysia D’Cor, Jessica Cowden, Tarun Saluja   +4 more
doaj   +1 more source

Place of clinical evaluation in the identification of obstructive coronary arteries lesions in patients with stable coronary artery disease: Part II

Российский кардиологический журнал, 2019
The article discusses the main stages of the diagnostic process (clinical evaluation, determination of pre-test probability, non-invasive tests). In this part of the review, two new approaches of non-invasive tests are considered.
A. N. Sumin,
doaj   +1 more source