Results 191 to 200 of about 2,881,753 (249)

Assessing the robustness and clinical evaluation of a deep-learning segmentation model for head and neck cancer. [PDF]

Front Oncol
Schanne DH, Cuenot L, Brüningk S, Reyes M, Elicin O.   +4 more
europepmc   +1 more source

Epigenetic reprogramming of lineage switching in cancer

FEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı, Burcu Akman, Ezgi Bağırsakçı, Nese Atabey, Serap Erkek‐Ozhan   +4 more
wiley   +1 more source

fNIRS as a Biomarker for Preoperative Assessment: Correlating Brain Activity with Clinical Evaluation for Lumbar Disc Herniation. [PDF]

Bioengineering (Basel)
Huang C, Li C, Su Z, Guo Q, Wang Q, Chen T, Wang Y, Yuan Z, Lu H.   +8 more
europepmc   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source

Clinical Evaluation of an Integrated Tri-Modal Transdermal Device for Enhanced Serum Absorption. [PDF]

J Cosmet Dermatol
Kim Y, Hong S, Chang K, Han S, Leung H, Lee JS, Jeon S, Jo H.   +7 more
europepmc   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Clinical evaluation of pediatric olfactory disorders: a review from etiology to management. [PDF]

Front Allergy
Trecca EMC, Reale M, Leone L, Cassano M, Della Volpe A, La Mantia I, Pagella F, Cantone E.   +7 more
europepmc   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Local dexamethasone and magnesium sulfate for postoperative pain management in septorhinoplasty: A clinical evaluation. [PDF]

JPRAS Open
Farahani PK, Karimi A, Yazdani D, Kiabi FH, Abbasi Z.   +4 more
europepmc   +1 more source