Results 181 to 190 of about 1,416,392 (341)
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Prospective analysis of clinical evolution in chronic urticaria: Persistence, remission, recurrence, and pruritus alone. [PDF]
World Allergy Organ J, 2022 Sánchez J, Álvarez L, Cardona R.
europepmc +1 more source
Evolution of cellular immune responses to hepatitis C virus during antiretroviral therapy and its clinical implications [PDF]
, 2010 Diepolder, Helmut M., Grüner, Norbert
core +1 more source
β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1
Molecular Oncology, EarlyView.Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero +8 more
wiley +1 more source
Predictors of clinical evolution of SARS-CoV-2 infection in hematological patients: A systematic review and meta-analysis. [PDF]
Hematol Oncol, 2023 Carrara E +16 more
europepmc +1 more source
THE FAST CLINICAL EVOLUTION OF A SPITZ NEVUS: THREE-YEAR FOLLOW-UP OF A CHILD
, 2017 Maria Cristina Pedrazini +2 more
openalex +1 more source
Genetic characterization of compensatory evolution in strains carrying rpoB Ser531Leu, the rifampicin resistance mutation most frequently found in clinical isolates [PDF]
, 2013 Gerrit Brandis, Diarmaid Hughes
openalex +1 more source
Molecular Oncology, EarlyView.AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou +5 more
wiley +1 more source
O Mundo da Saúde, 2019 Clinical outcomes of hospitalized elderly provide subsidies to prevent complications that interfere with quality of life. Objectives: to verify the sociodemographic characteristics and to analyze the associations between the diseases diagnosed at ...
Alexandre Lins Werneck +6 more
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