Results 21 to 30 of about 636,139 (316)

THE EVOLUTION OF TREATMENT AT THE ORTHOPEDICS AND REHABILITATION CLINIC

Wiadomości Lekarskie, 2020
Introduction: The last 20 years have been a period of huge changes in Polish healthcare, both in terms of medical progress as well as organization and financing. These changes, and especially the newly introduced queuing systems significantly influenced the changes in the profile of hospital admission. The aim: To analyze changes in the patient profile,
Joanna, Niezbecka-Zając, Karolina, Turżańska, Agnieszka, Posturzyńska, Anna, Horecka   +3 more
openaire   +3 more sources

Evolution of clinical trials for rheumatoid arthritis and spondyloarthritis

, 2018
Purpose of review The present review presents an overview of the evolution in trial design from mainly randomized placebo-controlled efficacy trials to more strategic clinical trials in rheumatoid arthritis and spondyloarthritis. Additionally, it relates
Marleen G.H. van de Sande, Ronald F. van Vollenhoven, van de Sande, Marleen G. H., van Vollenhoven, Ronald F.   +3 more
core   +1 more source

Avaliação ecocardiográfica evolutiva do infarto do miocárdio em ratos jovens e adultos Echocardiographic assessment of myocardial infarction evolution in young and adult rats

Arquivos Brasileiros de Cardiologia, 2008
FUNDAMENTO: A regeneração dos cardiomiócitos após o infarto do miocárdio (IM) é mais evidente em animais jovens; entretanto, não se sabe se é acompanhada de melhora funcional.
Francisco Cesar Pabis, Nelson Itiro Miyague, Julio César Francisco, Vinícius Woitowicz, Katherine Athayde Teixeira de Carvalho, José Rocha Faria-Neto, Valdir Ambrósio Moisés, Luiz César Guarita-Souza   +7 more
doaj   +1 more source

Constrained pattern of viral evolution in acute and early HCV infection limits viral plasticity

, 2011
Cellular immune responses during acute Hepatitis C virus (HCV) and HIV infection are a known correlate of infection outcome. Viral adaptation to these responses via mutation(s) within CD8+ T-cell epitopes allows these viruses to subvert host immune ...
Paul Klenerman, Malte Heeg, John, Mina, Pfafferott, K, James, Ian, Ulsenheimer, Axel, Helmut M. Diepolder, Lucas, A.D., Silvana Gaudieri, Heeg, M, Rauch, A, Ian James, John, M., Andri Rauch, Klenerman, P., James, I, Simon Mallal, Diepolder, HM, Heeg, Malte, John, M, Mallal, Simon, Lucas, Andrew, Nolan, D., Lucas, M., Heeg, M., Michaela Lucas, Diepolder, H.M., Mallal, S., Gaudieri, S, Lucas, M, Gaudieri, S., Nolan, David, Ulsenheimer, A, Lucas, A, David Nolan, Klenerman, Paul, Diepolder, Helmut M., Pfafferott, K., Klenerman, P, Rauch, A., Ulsenheimer, A., Pfafferott, Katja, Lucas, Michaela, Katja Pfafferott, Andrew Lucas, Rauch, Andri, Diepolder, Helmut M, Axel Ulsenheimer, Mina John, Helmut M Diepolder, Nolan, D, Mallal, S, James, I., Gaudieri, Silvana   +53 more
core   +1 more source

Evolution of the clinical electrocardiogram

Journal of the American College of Cardiology, 1989
To place this unique noninvasive technique in its proper perspective, it would seem appropriate that this brief review begin with the history of electrocardiography and include comments regarding its sensitivity and specificity, its role as a marker for heart disease, as a clue to anatomic, metabolic and hemodynamic abnormalities, its role as the ...
openaire   +2 more sources

Carcinomas and Carcinoid Tumors of the Lungs and Bronchi in Children and Adolescents: The EXPeRT Recommendations

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Primary lung carcinomas and bronchial carcinoid tumors (BC) are very rare malignancies in childhood. While typical BC and mucoepidermoid carcinomas are mostly low‐grade, localized tumors with a more favorable prognosis than in adults, necessitating avoidance of overtreatment, adenocarcinomas of the lung are often diagnosed at advanced disease ...
Michael Abele, Calogero Virgone, Michaela Kuhlen, Sabine Irtan, Yves Reguerre, Malgorzata Krawczyk, Ewa Bien, Tal Ben‐Ami, Maja Cesen, Ricardo Lopez‐Almaraz, Andrea Ferrari, Gianni Bisogno, Dominik T. Schneider, Abbas Agaimy, Constantin Lapa, Hubert Ducou le Pointe, Rainer Claus, Catherine Daniel, Ines B. Brecht, Daniel Orbach   +19 more
wiley   +1 more source

Clinical and laboratory status of patients with chronic Chagas disease living in a vector-controlled area in Minas Gerais, Brazil, before and nine years after aetiological treatment

Memorias do Instituto Oswaldo Cruz, 2009
Twenty-eight Chagas disease patients (CD), 22 with the indeterminate clinical form (IND) and six with the cardiac or digestive form (CARD/DIG), were treated with benznidazole and underwent clinical and laboratorial analysis before (IND and CARD/DIG) and ...
Marta de Lana, Leonardo A Lopes, Helen R Martins, Maria T Bahia, Girley F Machado-de-Assis, Ana P Wendling, Olindo A Martins-Filho, Roberto A Montoya, João CP Dias, Pedro Albajar-Viñas, José R Coura   +10 more
doaj   +1 more source

ERD Trends and clinical evolution.

, 2015
ERD trends and clinical evolution of the 11 analyzed patients. Underlined values represent statistical significance, with bold face/italics representing significant ERD decreases/increases. α-Evol: Evolution of the ERD in α band. β-Evol: Evolution of the
Luis Montesano (403779), Antonio Oliviero (771016), Javier Minguez (403780), Ángel Gil-Agudo (771015), Eduardo López-Larraz (771014)   +4 more
core   +1 more source

European Standard Clinical Practice Guideline and EXPeRT Recommendations for the Diagnosis and Management of Gastroenteropancreatic Neuroendocrine Neoplasms in Children and Adolescents

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Pediatric gastroenteropancreatic neuroendocrine neoplasms (GEP‐NENs) are extremely rare and clinically heterogeneous. Management has largely been extrapolated from adult practice. This European Standard Clinical Practice Guideline (ESCP), developed by the EXPeRT network in collaboration with adult NEN experts, provides (adult) evidence ...
Michaela Kuhlen, Calogero Virgone, Antje Redlich, Michael Abele, Ricardo Lopez‐Almaraz, Tal Ben‐Ami, Ewa Bien, Gianni Bisogno, Maja Mazic Cesen, Andrea Ferrari, Malgorzata A. Krawczyk, Yves Reguerre, Dominik T. Schneider, Ines B. Brecht, Charlotte Rigaud, Bilgehan Yalcin, Rainer Claus, Christian Vokuhl, Constantin Lapa, Jörg Fuchs, Segolene Hescot, Thomas Walter, Julien Hadoux, Daniel Orbach   +23 more
wiley   +1 more source

Health‐Related Quality of Life and Symptom Severity Among Patients With PIK3CA‐Related Overgrowth Spectrum: A Mixed‐Methods Study to Understand Real‐World Experience With Alpelisib Treatment

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background PIK3CA‐related overgrowth spectrum (PROS) includes several rare overgrowth disorders resulting from somatic gain‐of‐function mutations in PIK3CA. Despite treatment advances, including the recent approval of alpelisib for PROS in the United States, literature detailing the patient experience with PROS is limited.
Vamsi Bollu, Kaitlin LaGasse, Cory D. Saucier, Kimberly Raymond, Miranda Lauher‐Charest, Lauren Crowder, Beilei Cai, Mary Lisha Paul, Denise Adams   +8 more
wiley   +1 more source