Results 81 to 90 of about 636,139 (316)

Lobectomía pulmonar por puerto único Single port video-assisted thoracoscopic pulmonary lobectomy

open access: yesRevista Colombiana de Cirugía, 2012
La cirugía torácica asistida por video ha tenido un gran desarrollo en los últimos años en todo el mundo y, aunque en nuestro país no se cuenta con cifras al respecto, cada día se practican mas cirugías con esta técnica.
Mauricio Velásquez   +1 more
doaj  

Midwifery students views on the benefits of using clinical skills center [PDF]

open access: yes
Background: Clinical skills center provides an opportunity for students to increase their clinical skills and communication in a calm and controlled environment using a variety of teaching aids and models.
اسدزاده, فيروزه   +3 more
core  

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

Using the Influenza Patient-reported Outcome (FLU-PRO) diary to evaluate symptoms of influenza viral infection in a healthy human challenge model

open access: yesBMC Infectious Diseases, 2018
Background In clinical studies involving a healthy volunteer human challenge model, a valid and reliable measure to assess the evolution of patient-reported symptom type and severity following viral exposure is necessary.
Alison Han   +5 more
doaj   +1 more source

Plantaris a vestigial muscle, its corelation to muscular evolution and its clinical implications

open access: yes, 2020
Background: Muscular evolution in human is muscular adaptation from stiff quadrupedal walking to bipedalism. Transforming from pre hominid to hominid bipedals provide insights to mechanics of walking in human.
KG, Arunkumar   +2 more
core  

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

Statistical Models of the Protein Fitness Landscape: Applications to Protein Evolution and Engineering [PDF]

open access: yes, 2012
Understanding the protein fitness landscape is important for describing how natural proteins evolve and for engineering new proteins with useful properties.
Romero, Philip Anthony
core   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

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