Results 81 to 90 of about 636,139 (316)
Lobectomía pulmonar por puerto único Single port video-assisted thoracoscopic pulmonary lobectomy
La cirugía torácica asistida por video ha tenido un gran desarrollo en los últimos años en todo el mundo y, aunque en nuestro país no se cuenta con cifras al respecto, cada día se practican mas cirugías con esta técnica.
Mauricio Velásquez +1 more
doaj
Midwifery students views on the benefits of using clinical skills center [PDF]
Background: Clinical skills center provides an opportunity for students to increase their clinical skills and communication in a calm and controlled environment using a variety of teaching aids and models.
اسدزاده, فيروزه +3 more
core
Organoids in pediatric cancer research
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
Reciprocal control of viral infection and phosphoinositide dynamics
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
Background In clinical studies involving a healthy volunteer human challenge model, a valid and reliable measure to assess the evolution of patient-reported symptom type and severity following viral exposure is necessary.
Alison Han +5 more
doaj +1 more source
Plantaris a vestigial muscle, its corelation to muscular evolution and its clinical implications
Background: Muscular evolution in human is muscular adaptation from stiff quadrupedal walking to bipedalism. Transforming from pre hominid to hominid bipedals provide insights to mechanics of walking in human.
KG, Arunkumar +2 more
core
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Statistical Models of the Protein Fitness Landscape: Applications to Protein Evolution and Engineering [PDF]
Understanding the protein fitness landscape is important for describing how natural proteins evolve and for engineering new proteins with useful properties.
Romero, Philip Anthony
core +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source

