Results 141 to 150 of about 9,130,807 (289)

Nomogram predicting macroscopic finding with limited or no clinical implication in 19175 patients referred to esophagogastroduodenoscopy

open access: yes, 2016
Objective: The diagnostic yield of esophagogastroduodenoscopy (EGD) depends on appropriate patient selection. The aim of the current study was to create a nomogram predicting findings with limited or no clinical implication in patients referred to EGD ...
Bo Bendvold   +4 more
core   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

Laparoscopic surgery for a hydrocele of the canal of Nuck with an ovarian tumor: An extremely rare clinical finding. [PDF]

open access: yesClin Case Rep, 2022
Tominaga M   +15 more
europepmc   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

open access: yesFEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Exudative retinal detachment in COVID-19 - associated rhino-orbital mucormycosis - A rare clinical finding. [PDF]

open access: yesIndian J Ophthalmol, 2021
Sarkar S   +5 more
europepmc   +1 more source

Pleuroparenchymal fibroelastosis in heterogeneous clinical conditions: Clinicopathologic analysis of 7 cases

open access: yes, 2018
BACKGROUND AND AIMS: Pleuroparenchymal fibroelastosis (PPFE) is classified as a rare idiopathic interstitial pneumonia, and its clinicopathologic features remain unclear.
차윤진
core   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

open access: yesFEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee   +2 more
wiley   +1 more source

Improvement of islet transplantation in prevascularized muscle sinus tracts

open access: yesiScience
Summary: This study aimed to develop an optimal alternative site for islet transplantation, addressing the limitations of the current clinical standard, the intrahepatic site. In this study, prevascularized muscle sinus tracts (MSTs) in mice were created
Ming Jin   +11 more
doaj   +1 more source

Finding Leverage Groups [PDF]

open access: yes
A brief discussion of recent methods using the Hat Matrix for identifying leverage points, and clustering techniques for finding groups of data points is presented.
David E. Coleman
core  

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