Results 171 to 180 of about 9,130,807 (289)

Hemichorea as sole clinical finding in basal ganglia infarction: MRI findings

open access: yes, 2016
A transient occlusion of the proximal middle cerebral artery may cause a selective necrosis of the basal ganglia with sparing of the pyramid tract. This finding is due to the differences in oxygen consumption of gray and white brain matter.

core  

Smaller is better: nanobodies meet NMR

open access: yesFEBS Letters, EarlyView.
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley   +1 more source

Hyperlinear palms as a clinical finding in peanut allergy. [PDF]

open access: yesJ Allergy Clin Immunol Pract, 2020
Brar KK   +5 more
europepmc   +1 more source

Neutralization of the PTX3/CD44 axis suppresses TGF‐β1 signaling in kidney fibrosis

open access: yesFEBS Letters, EarlyView.
This study investigates how the PTX3/CD44 axis promotes kidney fibrosis by activating TGF‐β1 signaling. We demonstrate that the neutralizing antibody WHC‐001 effectively inhibits this pathway, suppressing myofibroblast activation and partial epithelial–mesenchymal transition (EMT).
Chao‐Chun Cheng   +8 more
wiley   +1 more source

Comparison of serological and clinical findings in Turkish patients with cystic echinococcosis

open access: yesHelminthologia, 2006
Yolasigmaz A.   +7 more
doaj   +1 more source

Addendum clinical guideline screening and prioritisation criteria

open access: yes, 2012
Clinical guideline prioritisation criteria are commonly utilised by various key international bodies and organisations in order to select clinical guidelines for development, appraisal or endorsement at national, regional and local level.
National Clinical Effectiveness Committee
core  

Inhibition of dipeptidyl peptidase 7 impairs lysophagy in LLOMe‐treated HepG2 cells

open access: yesFEBS Letters, EarlyView.
DPP7 inhibition delays ubiquitin‐dependent lysophagy by attenuating ubiquitin accumulation and the recruitment of SQSTM1 and LC3 to damaged lysosomes, resulting in delayed clearance of damaged lysosomes and impaired restoration of lysosomal homeostasis. Created using FigureLabs (Certificate ID: FL‐PUB‐20260922‐Z99XNX).
Na Yeon Park   +8 more
wiley   +1 more source

Thyroid lobe agenesis: a rare clinical finding. [PDF]

open access: yesJCEM Case Rep
Diaz-Cuadrado I   +3 more
europepmc   +1 more source

Finding a needle in the haystack: performing an in-depth literature search to answer a clinical question

open access: yes, 2014
Gwen S George, Laurie Anne Ferguson, Patricia F PearceLoyola University New Orleans, School of Nursing, New Orleans, LA, USAAbstract: Evidence-based practice requires clinicians to review current literature for evidence-based information that ...
Pearce PF, George GS, Ferguson LA
core  

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

open access: yesMolecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce   +11 more
wiley   +1 more source

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