Results 181 to 190 of about 591,252 (334)
Molecular Oncology, EarlyView.CircCCNB1 expression is down‐regulated in nasopharyngeal carcinoma (NPC); thus, less NF90 protein is bound to circCCNB1 and more binds to pri‐miRNAs, blocking their (pri‐miRNAs) binding to DGCR8 and inhibiting the processing and generation of miR‐15b‐5p/miR‐7‐1‐3p. Furthermore, decreased miR‐15b‐5p/miR‐7‐1‐3p promotes the expression of the target genes
Chunmei Fan +6 more
wiley +1 more source
Book Review: Genetics in Clinical Practice: New Directions for Nursing and Health Care. By D. H. Lea, J. F. Jenkins, and C. A. Francomano. Jones & Bartlett, Sudbury, MA, 1998, 300 pp. [PDF]
, 2000 Janet K. Williams
openalex +1 more source
Medical genetics in clinical practice.
South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1974 Two hundred and fifty-four patients were seen in the Genetic Clinics during 1973, the first full year of activity of the Department of Human Genetics, University of Cape Town. The current role of medical genetics in clinical practice is exemplified by an analysis and discussion of the problems presented by these individuals.S. Afr. Med.
Beighton, PH, Nelson, MM
openaire +3 more sources
Classification of acute myeloid leukemia based on multi‐omics and prognosis prediction value
Molecular Oncology, EarlyView.The Unsupervised AML Multi‐Omics Classification System (UAMOCS) integrates genomic, methylation, and transcriptomic data to categorize AML patients into three subtypes (UAMOCS1‐3). This classification reveals clinical relevance, highlighting immune and chromosomal characteristics, prognosis, and therapeutic vulnerabilities.
Yang Song +13 more
wiley +1 more source
The 2019 US medical genetics workforce: a focus on clinical genetics. [PDF]
Genet Med, 2021 Jenkins BD +12 more
europepmc +1 more source
Adverse prognosis gene expression patterns in metastatic castration‐resistant prostate cancer
Molecular Oncology, EarlyView.We aggregated a cohort of 1012 mCRPC tissue samples from 769 patients and investigated the association of gene expression‐based pathways with clinical outcomes. Loss of AR signaling, high proliferation, and a glycolytic phenotype were independently prognostic for poor outcomes, and an adverse transcriptional feature score incorporating these pathways ...
Marina N. Sharifi +26 more
wiley +1 more source
Artificial intelligence in clinical genetics. [PDF]
Eur J Hum GenetDuong D, Solomon BD.
europepmc +1 more source
Medical care in clinical genetics: an experience of decentralization in southern Brazil. [PDF]
Einstein (Sao Paulo), 2021 Meneghini KFD +5 more
europepmc +1 more source
Widening the spectrum of players affected by genetic changes in Wilms tumor relapse
iScienceSummary: Few studies investigated the genetics of relapsed Wilms tumor (WT), suggesting the SIX1 gene, the microRNA processing genes, and the MYCN network as possibly involved in a relevant percentage of relapses. We investigated 28 relapsing WT patients
Sara Ciceri +16 more
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