Results 221 to 230 of about 10,250,216 (364)

Tell me once, tell me soon: parents’ preferences for clinical genetics services for congenital heart disease

Genetics in Medicine, 2018
Nadine A. Kasparian, R. De Abreu Lourenço, D. Winlaw, G. Sholler, R. Viney, E. Kirk   +5 more
semanticscholar   +1 more source

Survivin and Aurora Kinase A control cell fate decisions during mitosis

Molecular Oncology, EarlyView.
Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir, Shalitha Wickrama Arachchige, Sally P. Wheatley   +2 more
wiley   +1 more source

The Clinical Genetics of Hemophilia B (Factor IX Deficiency). [PDF]

Appl Clin Genet, 2021
Miller CH.
europepmc   +1 more source

WS8.1 The first 1,000 CFTR genes sequenced in the Mayo Clinic Clinical Molecular Genetics Laboratory

, 2012
W. Edward Highsmith
openalex   +1 more source

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

Molecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir, Lukasz Arcimowicz, Lucia Martinkova, Vaclav Hrabal, Filip Zavadil Kokas, Tomas Henek, Martina Kucerikova, Ondrej Bonczek, Pavlina Zatloukalova, Lenka Hernychova, Philip J. Coates, Borivoj Vojtesek, David P. Lane   +12 more
wiley   +1 more source

Integrating genetics into medical curriculum: evaluating a dedicated clinical genetics module at Dow university of health sciences. [PDF]

BMC Med Educ
Hanif MI, Bari MF, Hussain M, Khan N, Hossain N, Quraishy MS, Kirmani S.   +6 more
europepmc   +1 more source

Long Noncoding RNAs: From Clinical Genetics to Therapeutic Targets?

Journal of the American College of Cardiology, 2016
R. Boon, Nicolas Jaé, L. Holdt, S. Dimmeler   +3 more
semanticscholar   +1 more source

Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity

Molecular Oncology, EarlyView.
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He, Chiara Testini, Neda Hekmati, Altea Bonello, Aglaia Schiza, Emmanuel Nwadozi, Mia Phillipson, Carina Strell, Michael Welsh   +8 more
wiley   +1 more source

Patient care practices for LGBTQ+ individuals in clinical genetics: A scoping review. [PDF]

J Genet Couns
Zayhowski K, Horowitz K, Bostrom M, Mittendorf KF, Kocher M, Austin JJ, MacFarlane IM.   +6 more
europepmc   +1 more source

Scope of professional roles for genetic counsellors and clinical geneticists in the United Kingdom : Position on behalf of the Association of Genetic Nurses and Counsellors and the Clinical Genetics Society. [PDF]

Eur J Hum Genet, 2023
Middleton A, Taverner N, Houghton C, Smithson S, Balasubramanian M, Elmslie F.   +5 more
europepmc   +1 more source