Results 221 to 230 of about 9,825,192 (424)

CircCCNB1 inhibits vasculogenic mimicry by sequestering NF90 to promote miR‐15b‐5p and miR‐7‐1‐3p processing in nasopharyngeal carcinoma

open access: yesMolecular Oncology, EarlyView.
CircCCNB1 expression is down‐regulated in nasopharyngeal carcinoma (NPC); thus, less NF90 protein is bound to circCCNB1 and more binds to pri‐miRNAs, blocking their (pri‐miRNAs) binding to DGCR8 and inhibiting the processing and generation of miR‐15b‐5p/miR‐7‐1‐3p. Furthermore, decreased miR‐15b‐5p/miR‐7‐1‐3p promotes the expression of the target genes
Chunmei Fan   +6 more
wiley   +1 more source

Predicting Atrial Fibrillation after Ischemic Stroke: Clinical, Genetics, and Electrocardiogram Modelling. [PDF]

open access: yesCerebrovasc Dis Extra, 2023
Poh MQW   +13 more
europepmc   +1 more source

Molecular genetics of nocturnal enuresis: clinical and genetic heterogeneity [PDF]

open access: bronze, 1998
Alexander von Gontard   +4 more
openalex   +1 more source

Classification of acute myeloid leukemia based on multi‐omics and prognosis prediction value

open access: yesMolecular Oncology, EarlyView.
The Unsupervised AML Multi‐Omics Classification System (UAMOCS) integrates genomic, methylation, and transcriptomic data to categorize AML patients into three subtypes (UAMOCS1‐3). This classification reveals clinical relevance, highlighting immune and chromosomal characteristics, prognosis, and therapeutic vulnerabilities.
Yang Song   +13 more
wiley   +1 more source

Genomic findings of hypertrophic and dilated cardiomyopathy characterized in a Thai clinical genetics service. [PDF]

open access: yesPLoS One, 2022
Trachoo O   +12 more
europepmc   +1 more source

Adverse prognosis gene expression patterns in metastatic castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
We aggregated a cohort of 1012 mCRPC tissue samples from 769 patients and investigated the association of gene expression‐based pathways with clinical outcomes. Loss of AR signaling, high proliferation, and a glycolytic phenotype were independently prognostic for poor outcomes, and an adverse transcriptional feature score incorporating these pathways ...
Marina N. Sharifi   +26 more
wiley   +1 more source

Integrating clinical genetics in cardiology: Current practices and recommendations for education. [PDF]

open access: yesGenet Med, 2022
Scherr CL   +8 more
europepmc   +1 more source

Clinical applications of schizophrenia genetics: genetic diagnosis, risk, and counseling in the molecular era

open access: yesThe Application of Clinical Genetics, 2012
Gregory Costain1,2, Anne S Bassett1–41Clinical Genetics Research Program, Centre for Addiction and Mental Health, 2Institute of Medical Science, University of Toronto, 3Division of Cardiology, Department of Medicine and Department of Psychiatry,
Costain G, Bassett AS
doaj  

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