Results 41 to 50 of about 423,814 (311)

Clinical Pharmacogenetics Implementation Consortium (CPIC) Guideline for Dihydropyrimidine Dehydrogenase Genotype and Fluoropyrimidine Dosing: 2017 Update

, 2017
The purpose of this guideline is to provide information for the interpretation of clinical dihydropyrimidine dehydrogenase (DPYD) genotype tests so that the results can be used to guide dosing of fluoropyrimidines (5-fluorouracil and capecitabine ...
Schellens, Jan H M, Swen, Jesse J, Klein, T.E., Julia Barbarino, Kelly E. Caudle, Diasio, R.B., Caudle, K.E., Steven M. Offer, Amstutz, U., Schwab, M., Afd Pharmacoepi & Clinical Pharmacology, Barbarino, J., Schellens, J.H.M., Schwab, Matthias, Pharmacoepidemiology and Clinical Pharmacology, Linda M. Henricks, McLeod, H.L., Offer, S.M., Amstutz, Ursula, Swen, Jesse J., Jesse J. Swen, Henricks, L.M., Jan H.M. Schellens, Caudle, Kelly E, Klein, Teri E, Matthias Schwab, Barbarino, Julia, Henricks, Linda M, Robert B. Diasio, Swen, J.J., McLeod, Howard L, Howard L. McLeod, Offer, Steven M, Ursula Amstutz, Teri E. Klein, Diasio, Robert B   +35 more
core   +1 more source

European Standard Clinical Practice Guideline and EXPeRT Recommendations for the Diagnosis and Management of Gastroenteropancreatic Neuroendocrine Neoplasms in Children and Adolescents

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Pediatric gastroenteropancreatic neuroendocrine neoplasms (GEP‐NENs) are extremely rare and clinically heterogeneous. Management has largely been extrapolated from adult practice. This European Standard Clinical Practice Guideline (ESCP), developed by the EXPeRT network in collaboration with adult NEN experts, provides (adult) evidence ...
Michaela Kuhlen, Calogero Virgone, Antje Redlich, Michael Abele, Ricardo Lopez‐Almaraz, Tal Ben‐Ami, Ewa Bien, Gianni Bisogno, Maja Mazic Cesen, Andrea Ferrari, Malgorzata A. Krawczyk, Yves Reguerre, Dominik T. Schneider, Ines B. Brecht, Charlotte Rigaud, Bilgehan Yalcin, Rainer Claus, Christian Vokuhl, Constantin Lapa, Jörg Fuchs, Segolene Hescot, Thomas Walter, Julien Hadoux, Daniel Orbach   +23 more
wiley   +1 more source

Global Guideline for Type 2 Diabetes [PDF]

, 2014
There is now extensive evidence on the optimal management of diabetes, offering the opportunity of improving the immediate and long-term quality of life of those with diabetes.
Boulton, Andrew, Aschner Montoya, Pablo, Viswanathan, Vijay, Roglic, Gojka, Neil, Andrew, Ramachandran, Ambady, Van Crombrugge, Paul, Beck-Nielsen, Henning, Colagiuri, Stephen, Franz, Marion, Siminerio, Linda, Snoek, Frank, Ramaiya, Kaushik, Bennett, Peter, Manley, Susan, Sinclair, Alan, Bennet, Peter, Home, Philip, Marshall, Sally, Aschner, Pablo, Mbanya, Jean Claude, Sim, Kyra, Schaper, Nicolaas, Gagliardino, Juan Jose, Beck Nielsen, Henning, Crombrugge, Paul Van, McGill, Marg, Gadsby, Roger, Vespasiani, Giacomo, Colagiuri, Ruth   +29 more
core   +1 more source

Health‐Related Quality of Life and Symptom Severity Among Patients With PIK3CA‐Related Overgrowth Spectrum: A Mixed‐Methods Study to Understand Real‐World Experience With Alpelisib Treatment

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background PIK3CA‐related overgrowth spectrum (PROS) includes several rare overgrowth disorders resulting from somatic gain‐of‐function mutations in PIK3CA. Despite treatment advances, including the recent approval of alpelisib for PROS in the United States, literature detailing the patient experience with PROS is limited.
Vamsi Bollu, Kaitlin LaGasse, Cory D. Saucier, Kimberly Raymond, Miranda Lauher‐Charest, Lauren Crowder, Beilei Cai, Mary Lisha Paul, Denise Adams   +8 more
wiley   +1 more source

UK clinical guideline for the prevention and treatment of osteoporosis [PDF]

, 2022
The National Osteoporosis Guideline Group (NOGG) has revised the UK guideline for the assessment and management of osteoporosis and the prevention of fragility fractures in postmenopausal women, and men age 50 years and older.
Paskins
core   +1 more source

Clinical diagnostic and therapeutic guidelines of stroke neurorestoration (2020 China version)

Journal of Neurorestoratology, 2020
Stroke is the main cause of death and disability among Chinese, and neurorestoration is an effective therapeutic strategy for patients with stroke. In recent years, many achievements have been made in stroke neurorestoration, but viewpoints for managing ...
Xiaoling Guo, Qun Xue, Jianhua Zhao, Yi Yang, Yang Yu, Dezhong Liu, Jing Liu, Wenwu Yang, Linsen Mu, Ping Zhang, Tianyi Wang, Hongyan Han, Shoufeng Liu, Yuhua Zhu, Tao Wang, Chuanqiang Qu, Chuanqiang Qu   +16 more
doaj   +1 more source

Clinical and Biological Features of Response in Resistant Neuroblastoma to 131I‐Metaiodobenzylguanidine Radiotherapy in the Anti‐GD2 Immunotherapy Era

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background 131I‐metaiodobenzylguanidine (131I‐MIBG) radiotherapy is a key treatment for relapsed and refractory (R/R) neuroblastoma (NB). Patients with R/R disease treated in the modern era are increasingly exposed to anti‐GD2 immunotherapy, which exerts selective pressure and may modify both tumor cell state and microenvironment.
Benjamin J. Lerman, Katherine K. Matthay, Fabienne Hollinger, Catriona Black, Ann A. Lazar, Miguel Pampaloni, Steven G. DuBois, Kieuhoa T. Vo   +7 more
wiley   +1 more source

Improving the Applicability and Feasibility of Clinical Practice Guidelines in Primary Care: Recommendations for Guideline Development and Implementation

Risk Management and Healthcare Policy, 2021
Lu Han,1,2 Linan Zeng,1,2 Yanjun Duan,3 Kexin Chen,4 Jiajie Yu,5 Honghao Li,6 Qiusha Yi,1,2 Youping Li,5 Lingli Zhang1,2 1Department of Pharmacy/Evidence-Based Pharmacy Center, West China Second University Hospital, Sichuan University, Chengdu, Sichuan ...
Han L, Zeng L, Duan Y, Chen K, Yu J, Li H, Yi Q, Li Y, Zhang L   +8 more
doaj  

The brief summary of the practical guideline for the treatment of stage I–III periodontitis – according to the EFP clinical practice guideline (2020)

Fogorvosi Szemle, 2021
The recently introduced 2017 World Workshop on the Classification of Periodontitis, changed several definitions and diagnostic approaches. Those were summarized and published in the Hungarian scientific media last year. One of the key elements of the new
Claudia Paár, Boldizsár Bartha, Mária Eper, Zsombor Radóczy-Drajkó, Gábor Szabó, István Gera   +5 more
doaj   +1 more source

Time Toxicity in Wilms Tumor: Quantifying the Burden of Healthcare Interaction in the First Year After Diagnosis

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Wilms tumor (WT) treatment imposes a significant time burden on patients and their families. Time toxicity is a patient‐centered metric that quantifies the burden of healthcare interaction. We sought to define time toxicity in the first year after diagnosis of WT and hypothesized that it would increase as tumor stage and treatment ...
Caleb Q. Ashbrook, Veerain Gupta, Nicholas J. Clark, Vijay Rings, Lauren E. Corona, Douglass B. Clayton, Daniel J. Benedetti   +6 more
wiley   +1 more source