Results 61 to 70 of about 5,855,669 (305)

Clinical guidelines contribute to the health inequities experienced by individuals with intellectual disabilities [PDF]

open access: yes, 2012
<p><b>Background:</b> Clinical practice guidelines are developed to improve the quality of healthcare. However, clinical guidelines may contribute to health inequities experienced by disadvantaged groups.
Macfie, M.L.   +14 more
core   +2 more sources

Evaluation of accuracy, quality, and readability of information on hypothyroidism provided by different artificial intelligence chatbot models

open access: yesFrontiers in Public Health
ObjectiveThis study assessed the accuracy, quality, and readability of responses from three leading AI chatbots—ChatGPT-3.5, DeepSeek-V3, and Google Gemini-2.5—on the diagnosis, treatment, and long-term risks of adult hypothyroidism, comparing their ...
Ting Ruan   +4 more
doaj   +1 more source

Association Between Individualized Education for Kidney Replacement Therapy Modality Selection and Peritoneal Dialysis Initiation: A Cross‐Sectional Study

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Peritoneal dialysis (PD) is an established home‐based kidney replacement therapy (KRT), but its uptake remains low in Japan. We evaluated whether individualized education in a dedicated outpatient clinic was associated with the initiation of PD.
Yasuko Ito   +7 more
wiley   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

open access: yesFEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee   +7 more
wiley   +1 more source

Systematic review of economic evaluations and cost analyses of guideline implementation strategies [PDF]

open access: yes, 2007
Objectives To appraise the quality of economic studies undertaken as part of evaluations of guideline implementation strategies; determine their resources use; and recommend methods to improve future studies. Methods Systematic review of economic studies
Grimshaw, Jeremy   +7 more
core   +1 more source

Analysis of the Current Status of China's Adaptation Guidelines

open access: yesXiehe Yixue Zazhi
Objective  To analyze the current status of the development of adaptation guidelines in China, as well as their methodological quality and the reporting quality, in order to provide reference for the development of adaptation guidelines.
WANG Ling   +9 more
doaj   +1 more source

Clinical guidelines in Hematology [PDF]

open access: yesRevista Brasileira de Hematologia e Hemoterapia, 2011
Clinical guidelines are now a powerful tool in decision making in the complex process of healthcare. There is no absolute definition of its impact on the clinical outcomes and in different patient populations. Nevertheless, its role is unquestionable in the regulation and organization of the healthcare system as a whole.(1-8) Evidence-based clinical
openaire   +4 more sources

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Improvement of Lupus and Sjögren’s Syndrome Symptoms by Acupuncture Treatment: A Case Report

open access: yesJournal of Acupuncture Research
The present study aimed to report the case of a patient with systemic lupus erythematosus and Sjögren’s syndrome who was successfully treated with Korean medicine.
Ju-Hyun Lee   +4 more
doaj   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

open access: yesFEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg   +14 more
wiley   +1 more source

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