Results 81 to 90 of about 5,855,669 (305)

Diagnosis, staging and treatment of patients with oesophageal or oesophagogastric junction cancer: National Clinical Guideline No. 19: Summary

, 2019
This guideline is intended for all health professionals involved in the diagnosis, staging and treatment of patients with oesophageal or OGJ cancer. While the CEO, General Manager and the Clinical Director of the hospital have corporate responsibility ...
National Clinical Effectiveness Committee (NCEC)
core  

Global Guideline for Type 2 Diabetes [PDF]

, 2014
There is now extensive evidence on the optimal management of diabetes, offering the opportunity of improving the immediate and long-term quality of life of those with diabetes.
Boulton, Andrew, Aschner Montoya, Pablo, Viswanathan, Vijay, Roglic, Gojka, Neil, Andrew, Ramachandran, Ambady, Van Crombrugge, Paul, Beck-Nielsen, Henning, Colagiuri, Stephen, Franz, Marion, Siminerio, Linda, Snoek, Frank, Ramaiya, Kaushik, Bennett, Peter, Manley, Susan, Sinclair, Alan, Bennet, Peter, Home, Philip, Marshall, Sally, Aschner, Pablo, Mbanya, Jean Claude, Sim, Kyra, Schaper, Nicolaas, Gagliardino, Juan Jose, Beck Nielsen, Henning, Crombrugge, Paul Van, McGill, Marg, Gadsby, Roger, Vespasiani, Giacomo, Colagiuri, Ruth   +29 more
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Clinical Guideline for Nursing Care of Children with Head Trauma (HT): Study Protocol for a Sequential Exploratory Mixed-Method Study

Pediatric Health, Medicine and Therapeutics, 2020
Zeynab Kord,1 Nasrollah Alimohammadi,2 Soheila Jafari Mianaei,3 Ali Riazi,4 Behrooz Zarasvand5 1School of Nursing and Midwifery, Isfahan University of Medical Sciences, Isfahan, Iran; 2Critical Care Nursing Department, School of Nursing and Midwifery ...
Kord Z, Alimohammadi N, Jafari Mianaei S, Riazi A, Zarasvand B   +4 more
doaj  

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

National clinical guideline No. 3 [PDF]

, 2014
Clostridium difficile is the leading cause of infectious nosocomial diarrhoea in industrialised countries. It is a spore-forming anaerobic bacterium that is widely distributed in soil and the intestinal tracts of animals and is part of the normal ...

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Hypertensive disorders of pregnancy: a systematic review of international clinical practice guidelines. [PDF]

, 2014
BACKGROUND: Clinical practice guidelines (CPGs) are developed to assist health care providers in decision-making. We systematically reviewed existing CPGs on the HDPs (hypertensive disorders of pregnancy) to inform clinical practice.
Pels, A, Anouk Pels (667541), Tessa E. R. Gillon (667540), von Dadelszen, Peter, Magee, Laura A., MacDonell, K., Laura A. Magee (512185), Anouk Pels, Magee Laura A., Tessa E R Gillon, Gillon Tessa E. R., Peter von Dadelszen, MacDonell, K, Pels Anouk, von Dadelszen, P., von Dadelszen, P, Gillon, Tessa E. R., Gillon, TE, Pels, Anouk, von Dadelszen, Peter; id_orcid, Karen MacDonell, Karen MacDonell (667542), MacDonell Karen, MacDonell, Karen, Peter von Dadelszen (258508), von Dadelszen Peter, Magee, LA, Pels, A., Magee, L.A., Gillon, T.E.R., Laura A Magee   +30 more
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Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source

Transforming evidence-based clinical guidelines into implementable clinical decision support services: the CAREPATH study for multimorbidity management

Frontiers in Medicine
IntroductionThe CAREPATH Project aims to develop a patient-centered integrated care platform tailored to older adults with multimorbidity, including mild cognitive impairment (MCI) or mild dementia.
Mert Gencturk, Gokce B. Laleci Erturkmen, A. Emre Akpinar, A. Emre Akpinar, Omid Pournik, Bilal Ahmad, Theodoros N. Arvanitis, Theodoros N. Arvanitis, Wolfgang Schmidt-Barzynski, Tim Robbins, Ruben Alcantud Corcoles, Ruben Alcantud Corcoles, Pedro Abizanda, Pedro Abizanda, Pedro Abizanda   +14 more
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Improving the Applicability and Feasibility of Clinical Practice Guidelines in Primary Care: Recommendations for Guideline Development and Implementation

Risk Management and Healthcare Policy, 2021
Lu Han,1,2 Linan Zeng,1,2 Yanjun Duan,3 Kexin Chen,4 Jiajie Yu,5 Honghao Li,6 Qiusha Yi,1,2 Youping Li,5 Lingli Zhang1,2 1Department of Pharmacy/Evidence-Based Pharmacy Center, West China Second University Hospital, Sichuan University, Chengdu, Sichuan ...
Han L, Zeng L, Duan Y, Chen K, Yu J, Li H, Yi Q, Li Y, Zhang L   +8 more
doaj  

Cancer‐associated mutations in endometriosis reframe a benign disease through molecular oncology

Molecular Oncology, EarlyView.
This review aims to comprehensively analyse cancer‐associated somatic mutations (CAMs) present in endometriotic lesions, emphasizing their biological roles, spatial distribution and implications for translational applications in medicine. By contextualizing a benign state within a genomic framework, this analysis seeks to establish its value as a ...
Clarissa Mujacic, Maria Concetta Vitale, Rita Siino, Emilia Di Giovanni, Carla Ferrante Bannera, Enrico Di Marco, Andrea Gottardo, Tancredi Didier Bazan Russo, Nadia Barraco, Alessandro Perez, Valerio Gristina, Antonio Galvano, Giuseppe Badalamenti, Antonio Russo, Viviana Bazan, Lorena Incorvaia   +15 more
wiley   +1 more source