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Addendum clinical guideline screening and prioritisation criteria
Clinical guideline prioritisation criteria are commonly utilised by various key international bodies and organisations in order to select clinical guidelines for development, appraisal or endorsement at national, regional and local level.
National Clinical Effectiveness Committee
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A case for clarity, consistency, and helpfulness : state-of-the-art clinical practice guidelines in endocrinology using the grading of recommendations, assessment, development, and evaluation system [PDF]
CONTEXT: The Endocrine Society, and a growing number of other organizations, have adopted the Grading of Recommendations, Assessment, Development, and Evaluation (GRADE) system to develop clinical practice guidelines and grade the strength of ...
Vigersky, R. A. +13 more
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Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach +9 more
wiley +1 more source
Disability Equipment Program : Clinical Guidelines
A clinical guideline for professional in the use of aids for daily living.Aged and Disability ...
Clinical Reference Group
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Decentralised Clinical Guidelines Modelling with Lightweight Coordination Calculus
Background:Clinical protocols and guidelines have been considered as a major means to ensure that cost-effective services are provided at the point of care.
Lewis, Paul +3 more
core +1 more source
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang +9 more
wiley +1 more source
CEACAM1 participation in breast cancer progression
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin +3 more
wiley +1 more source
Diagnosis and staging of patients with ovarian cancer: National Clinical Guideline No. 20
This guideline is intended for all health professionals involved in the diagnosis and staging of patients with ovarian cancer and health professionals working in Genetics Services.
Department of Health
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This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi +6 more
wiley +1 more source
Diagnosis and staging of patients with ovarian cancer National Clinical Guideline No. 20: Summary
This summary should be read in conjunction with the full version National Clinical Guideline. The full version is available at: https://health.gov.ie/national-patient-safety-office/ncec/national-clinical-guidelines/. The complete list of appendices can
Department of Health
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