Results 1 to 10 of about 9,065,236 (261)

Identification of Key Proteins from the Alternative Lengthening of Telomeres-Associated Promyelocytic Leukemia Nuclear Bodies Pathway

Biology, 2022
Alternative lengthening of telomeres-associated promyelocytic leukemia nuclear bodies (APBs) are a hallmark of telomere maintenance. In the last few years, APBs have been described as the main place where telomeric extension occurs in ALT-positive cancer
Isaac Armendáriz-Castillo, Katherine Hidalgo-Fernández, Andy Pérez-Villa, Jennyfer M. García-Cárdenas, Andrés López-Cortés, Santiago Guerrero   +5 more
doaj   +1 more source

Ivermectin treatment for Strongyloides infection in patients with COVID-19

Canada Communicable Disease Report, 2021
Ivermectin, an antiparasitic agent, is not recommended for prophylaxis or treatment of coronavirus disease 2019 (COVID-19). Inappropriate use of ivermectin for treatment of COVID-19 may make it less available for patients with serious parasitic ...
Elizabeth Leung, Sumit Raybardhan, Christopher Graham, Caroline Nott, Bradley J Langford, Nisha Andany, William Ciccotelli, Sumon Chakrabarti, Isaac I Bogoch, Wayne L Gold, Menaka Pai, Andrew M Morris, Anne McCarthy   +12 more
doaj   +1 more source

Adapting global evidence-based practice guidelines to the Egyptian healthcare context: the Egyptian Pediatric Clinical Practice Guidelines Committee (EPG) initiative

Bulletin of the National Research Centre, 2023
Background In Egypt, academic organizations, professional societies, and research groups develop clinical practice guidelines (CPGs) in order to improve patient quality care and safety.
Ashraf Abdel Baky, Tarek E. I. Omar, Yasser Sami Amer, the Egyptian Pediatric Clinical Practice Guidelines Committee (EPG)   +3 more
doaj   +1 more source

Traitement à l’ivermectine pour l’infection à Strongyloides chez les patients atteints de COVID-19

Canada Communicable Disease Report, 2021
L’ivermectine, un agent antiparasitaire, n’est pas recommandé pour la prophylaxie ou le traitement de la maladie à coronavirus 2019 (COVID-19).
Elizabeth Leung, Sumit Raybardhan, Christopher Graham, Caroline Nott, Bradley J Langford, Nisha Andany, William Ciccotelli, Sumon Chakrabarti, Isaac I Bogoch, Wayne L Gold, Menaka Pai, Andrew M Morris, Anne McCarthy   +12 more
doaj   +1 more source

The close interaction between hypoxia-related proteins and metastasis in pancarcinomas

Scientific Reports, 2022
Many primary-tumor subregions exhibit low levels of molecular oxygen and restricted access to nutrients due to poor vascularization in the tissue, phenomenon known as hypoxia.
Andrés López-Cortés, Lavanya Prathap, Esteban Ortiz-Prado, Nikolaos C. Kyriakidis, Ángela León Cáceres, Isaac Armendáriz-Castillo, Antonella Vera-Guapi, Verónica Yumiceba, Katherine Simbaña-Rivera, Gabriela Echeverría-Garcés, Jennyfer M. García-Cárdenas, Andy Pérez-Villa, Patricia Guevara-Ramírez, Andrea Abad-Sojos, Jhommara Bautista, Lourdes Puig San Andrés, Nelson Varela, Santiago Guerrero   +17 more
doaj   +1 more source

Machine learning for screening prioritization in systematic reviews: comparative performance of Abstrackr and EPPI-Reviewer

Systematic Reviews, 2020
Background Improving the speed of systematic review (SR) development is key to supporting evidence-based medicine. Machine learning tools which semi-automate citation screening might improve efficiency.
Amy Y. Tsou, Jonathan R. Treadwell, Eileen Erinoff, Karen Schoelles   +3 more
doaj   +1 more source

Molecular Pathogenesis and New Therapeutic Dimensions for Spinal Muscular Atrophy

Biology, 2022
The condition known as 5q spinal muscular atrophy (SMA) is a devastating autosomal recessive neuromuscular disease caused by a deficiency of the ubiquitous protein survival of motor neuron (SMN), which is encoded by the SMN1 and SMN2 genes.
Andrés López-Cortés, Gabriela Echeverría-Garcés, María José Ramos-Medina   +2 more
doaj   +1 more source

More Guidelines than states: variations in U.S. lead screening and management guidance and impacts on shareable CDS development

BMC Public Health, 2020
Background Pediatric lead exposure in the United States (U.S.) remains a preventable public health crisis. Shareable electronic clinical decision support (CDS) could improve lead screening and management. However, discrepancies between federal, state and
Jeremy J. Michel, Eileen Erinoff, Amy Y. Tsou   +2 more
doaj   +1 more source

Evaluación de la calidad de guías de práctica clínica para el tratamiento de psoriasis mediante la herramienta AGREE II

Actas Dermo-Sifiliográficas, 2022
Resumen: Introducción: Las guías de práctica clínica (GPCs) se han desarrollado para apoyar a los profesionales de la salud a brindar una excelente atención médica a sus pacientes.
C. Montesinos-Guevara, A. Andrade Miranda, E. Bedoya-Hurtado, C.M. Escobar Liquitay, J.V.A. Franco, D. Simancas-Racines, Y. Sami Amer, R.W.M. Vernooij, A. Viteri-García   +8 more
doaj   +1 more source

Clinical guidelines contribute to the health inequities experienced by individuals with intellectual disabilities [PDF]

, 2012
<p><b>Background:</b> Clinical practice guidelines are developed to improve the quality of healthcare. However, clinical guidelines may contribute to health inequities experienced by disadvantaged groups.
Macfie, M.L., Macfie Marjorie L, Mizen Lindsay AM, Melville, C., Cooper, S.-A., Findlay, L., Lindsay AM Mizen, Cooper Sally-Ann, Marjorie L Macfie, Linda Findlay, Sally-Ann Cooper, Craig A Melville, Findlay Linda, Mizen, L.A.M., Melville Craig A   +14 more
core   +2 more sources