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Knowledge, perceptions and confidence of physicians and pharmacists towards pharmacogenetics practice in Kuwait [PDF]
PLoS ONE, 2018 BACKGROUND:Pharmacogenetics practice has been successfully implemented in many developed countries to enhance personalized medicine and improve clinical and economic outcomes.
Abdullah Albassam +2 more
exaly +2 more sources
Pharmacogenetics of Antidepressants [PDF]
Frontiers in Pharmacology, 2011 Up to 60% of depressed patients do not respond completely to antidepressants (ADs) and up to 30% do not respond at all. Genetic factors contribute for about 50% of the AD response. During the recent years the possible influence of a set of candidate genes as genetic predictors of AD response efficacy was investigated by us and others.
Edoardo Spina +2 more
exaly +7 more sources
Pharmacogenetics and Forensic Toxicology: A New Step towards a Multidisciplinary Approach
Toxics, 2021 Pharmacogenetics analyzes the individual behavior of DNA genes after the administration of a drug. Pharmacogenetic research has been implemented in recent years thanks to the improvement in genome sequencing techniques and molecular genetics. In addition
Nunzio Di Nunno +4 more
doaj +1 more source
British Medical Bulletin, 1999 Inter-individual variability in drug response is a major clinical problem. Adverse drug reactions (ADRs) are common, are responsible for a number of debilitating side effects following drug therapy and are a significant cause of death. It is now clear that much of the observed variability in drug response has a genetic basis, arising as a result of ...
Wolf, C. Roland, Smith, Gillian
openaire +2 more sources
Pharmacogenetics: Knowledge assessment amongst Syrian pharmacists and physicians
BMC Health Services Research, 2021 Background Pharmacogenetics targets genetic variations that influence drug response. It is relatively a new science that has not been vastly employed in most developing countries including Syria. Therefore we aimed at evaluating the depth of knowledge in
Lina Albitar, Ghalia Abou Alchamat
doaj +1 more source
Frontiers in Pharmacology, 2020 Human leukocyte antigen (HLA) class I and II are known to have association with severe cutaneous adverse reactions (SCARs) when exposing to certain drug treatment. Due to genetic differences at population level, drug hypersensitivity reactions are varied,
Patompong Satapornpong +23 more
doaj +1 more source
Pharmacogenetic testing in oncology: a Brazilian perspective
Clinics, 2018 Pharmacogenetics, a major component of individualized or precision medicine, relies on human genetic diversity. The remarkable developments in sequencing technologies have revealed that the number of genetic variants modulating drug action is much higher
Guilherme Suarez-Kurtz
doaj +1 more source
The pharmacogenetics of imanitib [PDF]
Genome Medicine, 2010 Imatinib mesylate (IM), a tyrosine kinase inhibitor, is one of the first molecularly targeted therapies to have been used in the clinic. It has proven to be efficient in the treatment of chronic myeloid leukemia and also in other malignancies that involve expression of a tyrosine kinase.
Dulucq, Stéphanie, Krajinovic, Maja
openaire +2 more sources
From pharmacogenetics to pharmaco-omics: Milestones and future directions
HGG Advances, 2022 The origins of pharmacogenetics date back to the 1950s, when it was established that inter-individual differences in drug response are partially determined by genetic factors.
Chiara Auwerx +3 more
doaj +1 more source
Some aspects of genetics and pharmacogenetics understanding by pharmacy students in Ukraine
Egyptian Journal of Medical Human Genetics, 2015 Background: Prescription and administration of drugs are still carried out without taking into consideration the individual’s needs of a particular patient on the post-Soviet territory.
O.V. Filiptsova +2 more
doaj +1 more source