Results 11 to 20 of about 34,080 (270)

Pharmacogenetics [PDF]

open access: yesHuman Molecular Genetics, 2001
Pharmacogenetics is the variability of drug response due to inherited characteristics in individuals. Drug metabolizing enzymes have been studied for decades, first as chemical reactions and, more recently, as specific polymorphisms of known molecules.
McCarthy, Alun
openaire   +3 more sources

Pharmacogenetics in Clinical Practice

open access: yesPrague Medical Report, 2012
Pharmacogenetics is a discipline that investigates how genetic variation relates to the drug efficacy and safety. The goal of pharmacogenetics is a personalized treatment, where according to genotype we would be able to prescribe the most effective drug ...
Hana Bakhouche, O. Slanař
doaj   +2 more sources

One Step Ahead in Realizing Pharmacogenetics in Low- and Middle-Income Countries: What Should We Do? [PDF]

open access: yesJournal of Multidisciplinary Healthcare
Yudisia Ausi,1,2 Melisa Intan Barliana,2,3 Maarten J Postma,3,4 Auliya A Suwantika3,5 1Doctor Program in Pharmacy, Faculty of Pharmacy, Universitas Padjadjaran, Jatinangor, Indonesia; 2Department of Biological Pharmacy, Faculty of Pharmacy, Universitas ...
Ausi Y   +3 more
doaj   +1 more source

Pharmacogenetics of antipsychotic adverse effects: Case studies and a literature review for clinicians

open access: yesNeuropsychiatric Disease and Treatment, 2007
Adriana Foster1, Zixuan Wang2, Manzoor Usman1, Edna Stirewalt1, Peter Buckley11Department of Psychiatry and Health Behavior and 2Department of Medicine and Pathology, Medical College of Georgia, Augusta, GA, USAAbstract: There is a growing body of ...
Adriana Foster   +4 more
doaj   +1 more source

Pharmacogenetics and the Pharmacy Profession: A Sociological Exploration [PDF]

open access: yes, 2012
Pharmacy, particularly in the community setting, has been subject to significant changes over the last three decades. Running concurrently to these changes has been the development of the field of pharmacogenetics, or ‘personalised medicine’, which is ...
Jamie, Kimberly
core   +6 more sources

Initial assessment of the benefits of implementing pharmacogenetics into the medical management of patients in a long-term care facility

open access: yesPharmacogenomics and Personalized Medicine, 2016
Juan-Sebastian Saldivar, David Taylor, Elaine A Sugarman, Ali Cullors, Jorge A Garces, Kahuku Oades, Joel Centeno AltheaDx, San Diego, CA, USA Abstract: The health care costs associated with prescription drugs are enormous, particularly in patients with ...
Saldivar JS   +6 more
doaj   +1 more source

Pharmacogenetics of Lethal Opioid Overdose: Review of Current Evidence and Preliminary Results from a Pilot Study [PDF]

open access: yes, 2023
There has been a worldwide substantial increase in accidental opioid-overdose deaths. The aim of this review, along with preliminary results from our pilot study, is to highlight the use of pharmacogenetics as a tool to predict causes of accidental ...
Bernard Le Foll   +11 more
core   +1 more source

Pharmacogenetics to Avoid Adverse Reactions in Cardiology: Ready for Implementation?

open access: yes, 2021
Cardiovascular Diseases (CVs) are one of the main causes of mortality and disability around the world. Advances in drug treatment have greatly improved survival and quality of life in the past decades, but associated adverse events remain a relevant ...
Sara Salvador-Martín   +1 more
core   +1 more source

Pharmacogenetics of osteoporosis [PDF]

open access: yesBest Practice & Research Clinical Endocrinology & Metabolism, 2010
Osteoporosis is a complex bone disorder with a strong genetic basis. The genetics of osteoporosis encompasses two main areas: genetics of disease susceptibility and pharmacogenetics of drug response. The former has been widely studied in the past few decades, while the latter is still largely untouched.
MARINI, FRANCESCA, BRANDI, MARIA LUISA
openaire   +8 more sources

Engineering a folic acid-decorated ultrasmall gemcitabine nanocarrier for breast cancer therapy: Dual targeting of tumor cells and tumor-associated macrophages

open access: yesActa Pharmaceutica Sinica B, 2022
Combination of passive targeting with active targeting is a promising approach to improve the therapeutic efficacy of nanotherapy. However, most reported polymeric systems have sizes above 100 nm, which limits effective extravasation into tumors that are
Pearl Moharil   +12 more
doaj   +1 more source

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