Results 241 to 250 of about 5,841,868 (306)

Editorial: Advances in identifying individuals at clinical high risk (CHR) for psychosis: perspectives from North America

Frontiers in Psychiatry
Sarah I. Tarbox-Berry, Sarah I. Tarbox-Berry, Daniel J. A. Devoe, Daniel J. A. Devoe, Rishab Gupta, Rishab Gupta   +5 more
doaj   +1 more source

The Aging Blood: Cellular Origins, Circulating Drivers, and Therapeutic Potential

Aging and Cancer, EarlyView.
As a conduit linking all organs, the blood system both reflects and actively drives systemic aging. This review highlights how circulating pro‐aging and antiaging factors and age‐associated hematopoietic stem cell dysfunction contribute to immunosenescence and multi‐organ decline, positioning the hematopoietic system as a target for aging intervention.
Hanqing He, Jianwei Wang
wiley   +1 more source

Shift in sex and age of individuals at a clinical high risk (CHR) for psychosis: relation to differences in recruitment methods and effect on sample characteristics. [PDF]

Schizophrenia (Heidelb)
Farina EA, Mourgues-Codern C, Stimler K, Kenney J, Saxena A, Mukhtar H, Addington J, Bearden CE, Cadenhead KS, Cannon TD, Cornblatt B, Ellman L, Gold J, Keshavan M, Mathalon DH, Mittal VA, Perkins DO, Schiffman J, Silverstein SM, Strauss GP, Stone WS, Walker EF, Waltz J, Corlett P, Powers AR, Woods SW.   +25 more
europepmc   +1 more source

Natural Products as Geroprotective Modulators in Diabetic Nephropathy: A Mechanistic Framework Integrating Aging Hallmarks and the AMPK–SIRT1–Nrf2 Axis

Aging and Cancer, EarlyView.
Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu, Latif Adams, Eunice Ampem‐Danso, Justice Kumi, Abigail Aning, Fatima Hamidu, Mustapha Abdul Mumin Mohammed, Ayuba Nii Darku Ankrah, Seth Kwabena Amponsah   +8 more
wiley   +1 more source

Prognostic Impact of European LeukemiaNet Genetic Risk Stratification System in Adult Patients With Acute Myeloid Leukemia

Aging and Cancer, EarlyView.
This study aimed to evaluate the prognostic value of ELN2017 in predicting survival outcomes and to assess the impact of clinical and molecular factors such as age, FLT3 and NPM1 mutations, and allogeneic hematopoietic stem cell transplantation (allo‐HSCT).
Mobina Shrestha, Bishwas Mandal, Vishal Mandal, Asis Shrestha, Amir Babu Shrestha   +4 more
wiley   +1 more source

Serum NR1 and NR2 concentrations in first-episode schizophrenia and clinical high-risk for psychosis. [PDF]

BMC Psychiatry
Mao Z, Li F, Ge L, Hou W, Ding Y, Wang F, Wen Y, Wang X, Cheng Y, Hou W, Wang L, Shi X, Bo Q, Dong F.   +13 more
europepmc   +1 more source

Re‐Awakening Public Attention to the Silent Pandemic of Cancer Among Older Adults in Low‐ and Middle‐Income Countries

Aging and Cancer, EarlyView.
ABSTRACT As global populations age, cancer is increasingly becoming a leading cause of morbidity and mortality among older adults, particularly in low‐ and middle‐income countries (LMICs). Despite accounting for the majority of new cancer cases and deaths, older individuals remain underrepresented in cancer research, clinical guidelines, and health ...
Ibrahim Bidemi Abdullateef, Sunkanmi Folorunsho, Abdulazeez Opeyemi Abdulganiyu   +2 more
wiley   +1 more source

Transient pre-baseline antipsychotic exposure (TPAE) is a prognostic specifier in clinical high risk for psychosis: evidence from the PSYSCAN consortium study. [PDF]

Schizophrenia (Heidelb)
Raballo A, Poletti M, Preti A.
europepmc   +1 more source

Associations between attenuated auditory p300 event-related potential and cognitive basic symptoms in young people at clinical high risk for psychosis. [PDF]

Psychiatry Clin Neurosci
Martin JC, Schubert KO, Mathalon DH, Hartmann S, Clark SR.   +4 more
europepmc   +1 more source