Spectrophotometry for cerebrospinal fluid pigment analysis [PDF]
The use of spectrophotometry for the analysis of the cerebrospinal fluid (CSF) is reviewed. The clinically relevant CSF pigments--oxyhemoglobin and bilirubin--are introduced and discussed with regard to clinical differential diagnosis and potentially ...
Keir, G., Petzold, A., Sharpe, L.T.
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Clinical application of high throughput molecular screening techniques for pharmacogenomics. [PDF]
Genetic analysis is one of the fastest-growing areas of clinical diagnostics. Fortunately, as our knowledge of clinically relevant genetic variants rapidly expands, so does our ability to detect these variants in patient samples.
Schrijver, Iris, Wiita, Arun P
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Service evaluation to establish the sensitivity, specificity and additional value of broad-range 16S rDNA PCR for the diagnosis of infective endocarditis from resected endocardial material in patients from eight UK and Ireland hospitals [PDF]
Infective endocarditis (IE) can be diagnosed in the clinical microbiology laboratory by culturing explanted heart valve material. We present a service evaluation that examines the sensitivity and specificity of a broad-range 16S rDNA polymerase chain ...
Alshafi, K +8 more
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Liquid chromatography-tandem mass spectrometry - Application in the clinical laboratory [PDF]
This review provides a concise survey of liquid chromatography tandem mass spectrometry (LCTMS) as an emerging technology in clinical chemistry. The combination of two mass spectrometers with an interposed collision cell characterizes LCTMS as an ...
Ford RE +7 more
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Laboratory Medicine is Faced with the Evolution of Medical Practice [PDF]
Laboratory medicine and clinical medicine are co-dependent components of medicine. Laboratory medicine functions most effectively when focused through a clinical lens. Me dical practice as a whole undergoes change.
Adams +21 more
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Principles of Immunochemical Techniques Used in Clinical Laboratories [PDF]
Immunochemistry offers simple, rapid, robust yet sensitive, and in most cases, easily automated methods applicable to routine analyses in clinical laboratories. Immunochemical methods do not usually require extensive and destructive sample preparation or expensive instrumentation.
Marja E. Koivunen, Richard L. Krogsrud
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The perioperative immune response [PDF]
PURPOSE OF REVIEW A host of immune modulators are now available in clinical practice. The perioperative period is characterized by profound alterations in host immunity, which can result in poor outcomes, which include infection, cancer recurrence and
Akira +50 more
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Potentiation of thrombus instability: a contributory mechanism to the effectiveness of antithrombotic medications [PDF]
© The Author(s) 2018The stability of an arterial thrombus, determined by its structure and ability to resist endogenous fibrinolysis, is a major determinant of the extent of infarction that results from coronary or cerebrovascular thrombosis.
A Gast +66 more
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Ferritin in pediatric critical illness: a scoping review [PDF]
This scoping review aimed to elucidate and summarize the predictive role of serum ferritin in critical pediatric illness. The Preferred Reporting Items for Systematic reviews and Meta-Analyses methodology was employed to conduct a scoping review of 5 ...
Ivy Cerelia Valerie +2 more
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From the clinic to the lab (and back) : a call for laboratory research to optimize cognitive-behaviour treatment of pain [PDF]
Cognitive behavioural therapy (CBT) is the dominant psychological treatment for chronic pain. CBT covers a mixture of aims and a broad range of techniques, including attentional control, modification of maladaptive beliefs and coping strategies and ...
Moore, David J, Van Damme, Stefaan
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