Results 41 to 50 of about 734,729 (308)

Prevalence and Correlates of Zinc Deficiency Among Vietnamese Women of Reproductive Age in Ho Chi Minh City: A Single Hospital-Based Survey

Frontiers in Global Women's Health, 2021
Background and Objectives: Zinc is a micronutrient that plays an important role in metabolism, cell growth regulation, and differentiation. Vietnam has many population groups living in poverty.
Vinh Quang Nguyen, Phong Van Lam, Aya Goto, Tu Van T. Nguyen, Thanh Nhan T. Vuong, Tien Minh Nguyen, Minh Ha Nguyen, Anh Tuyet T. Truong, Truc Phuong T. Tran, Chien Duc Vo   +9 more
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Interim laboratory biosafety guidelines for handling and processing specimens associated with coronavirus disease 2019 (COVID-19) [PDF]

Updated May 12, 2021All clinical specimens may contain potentially infectious materials. Precautions should be taken when handling specimens suspected or confirmed to be positive for SARS-CoV-2, the virus that causes COVID-19.

core   +6 more sources

Review of the Changing Roles of Clinical Laboratory Scientists and Strategies for Curricular Innovation in the Era of Artificial Intelligence

Korean Journal of Clinical Laboratory Science
The rapid advances in artificial intelligence (AI) and robotic automation are bringing a paradigm shift to laboratory medicine. Although automation maximizes efficiency, it raises concerns regarding job security and the professional identity of clinical ...
Hee Sung KIM
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

CD4+ T cell exhaustion revealed by high PD-1 and LAG-3 expression and the loss of helper T cell function in chronic hepatitis B

BMC Immunology, 2019
Background Immune inhibitory receptors play an important role in chronic infections. However, little is known about their role in hepatitis B virus (HBV) infection.
Yuejiao Dong, Xuefen Li, Lu Zhang, Qiaoyun Zhu, Chunlei Chen, Jiaqi Bao, Yu Chen   +6 more
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Bacterial identification by clinical microbiology laboratory techniques.

, 2015
Typical temporal workflow of clinical microbiological laboratory to identify microbes from clinical samples based on phenotypic, biochemical, and culture-based techniques.
Ramya Srinivasan (690289), Susan V. Lynch (246918), Marina Volegova (690290), Ulas Karaoz (246903), Midori Kato-Maeda (163386), Steve Miller (30464), Rohan Nadarajan (690292), Eoin L. Brodie (246917), Joanna MacKichan (690291)   +8 more
core   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Public Health Laboratory Training Partner Handbook [PDF]

This Public Health Laboratory Training Partner (TrP) Handbook is meant to introduce some of the terms and available resources to training coordinators, biosafety officers, bioterrorism and chemical terrorism preparedness coordinators and others involved ...

core   +2 more sources