Results 141 to 150 of about 555,719 (297)

Protocol for German trial of Acyclovir and corticosteroids in Herpes-simplex-virus-encephalitis (GACHE) : a multicenter, multinational, randomized, double-blind, placebo-controlled German, Austrian and Dutch trial [ISRCTN45122933]

, 2008
Background The treatment of Herpes-simplex-virus-encephalitis (HSVE) remains a major unsolved problem in Neurology. Current gold standard for therapy is acyclovir, a drug that inhibits viral replication.
Menon, Sanjay, Meyding-Lamadé Uta, Luntz, Steffen, Luntz Steffen, Hacke Werner, de Gans, Jan, Eva Schielke, Sanjay Menon, Hacke, Werner, Schielke, Eva, Jensen, Katrin, Meyding-Lamadé, Uta, Schmutzhard Erich, Menon Sanjay, Norbert Victor, Schmutzhard, Erich, Chin-Hee Chung, Victor, Norbert, Jensen Katrin, Martinez-Torres Francisco, Katrin Jensen, Schielke Eva, Maria Pritsch, Jenetzky Ekkehart, Chung Chin-Hee, Pritsch Maria, Martinez Torres, Francisco Javier, Werner Hacke, Erich Schmutzhard, Jenetzky, Ekkehart, Victor Norbert, de Gans Jan, Chung, Chin-Hee, null null, Francisco Martinez-Torres, Steffen Luntz, Uta Meyding-Lamadé, Pritsch, Maria, Martinez-Torres, Francisco, Ekkehart Jenetzky, Jan de Gans   +40 more
core   +1 more source

Developmental and Epileptic Encephalopathy due to Biallelic Pathogenic Variants in PIGM

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective PIGM encodes a critical enzyme in the glycosylphosphatidylinositol (GPI)‐anchor biosynthesis pathway. While promoter‐region mutations in PIGM have been associated with a relatively mild phenotype characterized by portal vein thrombosis and absence seizures, recent evidence suggests that coding‐region mutations result in a more severe
Júlia Sala‐Coromina, Anna Marcé‐Grau, Barbara Masotto, Marta Codina, Lamia BenJemaa, Yasmina Elaribi, Mónica Martinez‐Gallo, Roger Colobran, Angel Sanchez‐Montañez, Irene Valenzuela, Yoshiko Murakami, Alfons Macaya   +11 more
wiley   +1 more source

[The anti-IgLON5 syndrome in clinical neurology-Report of two cases]. [PDF]

Nervenarzt, 2022
Niederschweiberer J, Schumacher NU, Kumpfmüller D, Lingg C, Graf S, Ikenberg B, Mühlau M, Lingor P, Hemmer B, Knier B.   +9 more
europepmc   +1 more source

Accuracy of dementia diagnosis - a direct comparison between radiologists and a computerized method

, 2008
There has been recent interest in the application of machine learning techniques to neuroimaging-based diagnosis. These methods promise fully automated, standard PC-based clinical decisions, unbiased by variable radiological expertise.
Jack, Clifford R., Jack, C. R., Patel, A.C., Frackowiak, R.S.J., Fox, Nick C., Fox, N.C., Fox, N. C., Mitchell, L. A., Good, C.D., Chen, Frances S., Frackowiak, R. S. J., Mader, I., Chen, F, Mitchell, L.A., Stonnington, C.M., Stonnington, Cynthia M., Patel, A. C., Ashburner, J., Frackowiak, Richard S. J., Barnes, Josephine, Klöppel, Stefan, Chu, C., Roberts, C.C., Mader, Irina, Barnes, J., Good, C. D., Stonnington, C. M., Chu, Carlton, Klöppel, S., Chen, F., Ashburner, John, Roberts, C. C., Jack, C.R.J.   +32 more
core   +1 more source

Efficacy of Intermittent Theta‐Burst Stimulation for Prolonged Disorders of Consciousness: A Prospective, Randomized, Controlled Trial

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Emerging evidence suggests that low‐frequency neural oscillations are dynamically regulated by consciousness levels, with the recovery of low cortical activity potentially serving as a neurophysiological substrate for conscious emergence. Targeted enhancement of these low‐frequency rhythms in patients with disorders of consciousness
Chuan Xu, Jun Hu, Qianqian Wu, Min Wu, Yamei Yu, Hangcheng Li, Jian Gao, Jingqi Li, Nai Ding, Jie Yu, Benyan Luo   +10 more
wiley   +1 more source

Impact of country self citation on the ranking of the top 50 countries in clinical neurology. [PDF]

eNeurologicalSci, 2021
Bardeesi AM, Jamjoom AAB, Sharab MA, Jamjoom AB.   +3 more
europepmc   +1 more source

FDG‐PET Associations With Disease Severity and Outcomes in NMDA‐Receptor IgG Autoimmune Encephalitis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Patients with N‐methyl‐D‐aspartate (NMDA) receptor‐immunoglobulin G (IgG) autoimmune encephalitis (NMDAR‐IgG AE) demonstrate occipital lobe hypometabolism on baseline brain fluorodeoxyglucose‐positron emission tomography (bFDG‐PET).
Jonathan K. Lee, Jeffrey Lambe, Scott Johnson, Akua Abrah, Jennifer Bullen, Jeffrey A. Cohen, Tatchaporn Ongphichetmetha, Amy Kunchok   +7 more
wiley   +1 more source

Epilepsy‐Associated Variants of a Single SCN1A Codon Exhibit Divergent Functional Properties

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Pathogenic variants in SCN1A, which encodes the voltage‐gated sodium channel NaV1.1, are associated with multiple epilepsy syndromes exhibiting a range of clinical severity. SCN1A variants are reported in different syndromes, including Dravet syndrome, which is associated with loss‐of‐function, whereas neonatal/infantile‐onset ...
Lanie N. Liebovitz, Christopher H. Thompson, Linda C. Laux, Alfred L. George Jr.   +3 more
wiley   +1 more source

Erratum: Scoping Review: Innovations in Clinical Neurology Education. [PDF]

Neurol Educ, 2023
europepmc   +1 more source

Posterior Cortical Atrophy in the Asia‐Pacific: A Report From the PCA Asian Workgroup

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Posterior Cortical Atrophy (PCA) is a distinct dementia syndrome primarily affecting spatial abilities and visual processing. It is associated with degeneration in the posterior part of the brain. PCA is subclassified into PCA‐pure and PCA‐plus syndromes based on consensus criteria.
Yuttachai Likitjaroen, Ya‐Ting Chang, Levinia Lim, Pai‐Yi Chiu, Jung‐Lung Hsu, SangYun Kim, Wataru Narita, Na Young Ryoo, Kyoko Suzuki, Nagaendran Kandiah, Sebastian Crutch, Ming‐Chyi Pai   +11 more
wiley   +1 more source