Results 61 to 70 of about 929,194 (283)

Perspectives of nanotechnologies in clinical neurology

Анналы клинической и экспериментальной неврологии, 2017
Nanotechnologies is a new and rapidly developing field of science and engineering related to targeted manipulation of objects sized within the nano-diapason (1091012 m); this means principally new characteristics and qualities of the respective systems ...
R. D. Seifulla, Z. A. Suslina, E. V. Kulykova, E. K. Kim, A. B. Timofeev, S. N. Illarioshkin, E. A. Rozhkova   +6 more
doaj   +1 more source

NKCC1: A key regulator of glioblastoma progression

Molecular Oncology, EarlyView.
Glioblastoma (GBM) progression is driven by disrupted chloride cotransporter homeostasis. NKCC1 is highly expressed in stem‐like, astrocytic, and progenitor cells, correlating with earlier recurrence, while overall survival remains unaffected. NKCC1 serves as a prognostic marker and potential therapeutic target, linking chloride transporter imbalance ...
Anja Thomsen, Diana Freitag, Madlen Haase, Christian Senft, Falko Schwarz, Silke Keiner   +5 more
wiley   +1 more source

Factors associated with attitudes toward research MRI in older Asian Americans

Alzheimer’s & Dementia: Translational Research & Clinical Interventions
INTRODUCTION South Asian (SA) and East Asian (EA) older adults represent the fastest‐growing racial/ethnic groups of Americans at risk for dementia. While recruiting older SA adults into a brain health study, we encountered unexpected hesitancy toward ...
Karthik J Kota, Alice Dawson, Julia Papas, Victor Sotelo, Guibin Su, Mei‐Ling Li, Woowon Lee, Jaunis Estervil, Melissa Marquez, Shromona Sarkar, Lisa Lanza Lopez, William T. Hu   +11 more
doaj   +1 more source

Targeting TNBC: core–shell polycationic polyurea dendrimers with inherent anticancer activity

FEBS Open Bio, EarlyView.
Core–shell polycationic PURE dendrimers were tested in TNBC‐derived tumor models. Both formulations selectively targeted TNBC and effectively reduced tumor volume. PUREG4‐OEI48 suppressed tumor growth without detectable toxicity, whereas PUREG4‐OCEI24, despite showing efficacy, induced hepatic toxicity.
Adriana Cruz, Bruna Abreu, Cindy Mendes, Catarina Freitas‐Dias, Filipe Gonçalves, Fernanda Silva, José Ramalho, Saudade André, Vasco D. B. Bonifácio, Jacinta Serpa   +9 more
wiley   +1 more source

Nomogram to predict 1-year cognitive decline after stent placement for unruptured intracranial aneurysms

iScience
Summary: New iatrogenic cerebral infarcts (NICIs) are common findings on diffusion-weighted magnetic resonance imaging (DWI) following stent placement for unruptured intracranial aneurysms (UIAs) and may contribute to cognitive decline (CD).
Wenqiang Li, Chao Wang, Yuzhao Lu, Junfan Chen, Wenbin Li, Yunpeng Liu, Ziqing Zhang, Zeping Jin, Yiqi Liu, Song Tan, Zhiwei Zhang, Xiaofei Huang, Cong Ding, Linfeng Zhang, Jian Liu, David M. Hasan, Yang Wang   +16 more
doaj   +1 more source

Pioglitazone plus (−)‐epigallocatechin gallate: a novel approach to enhance osteogenic performance in aged bone marrow mesenchymal stem cells

FEBS Open Bio, EarlyView.
Aged human bmMSCs are seeded in the scaffold. Osteoblastic induction can slightly increase cell's bone‐forming activity to produce bone‐like tissues, shown as the sporadic xylenol orange‐stained spots (the lower left image). Notably, pioglitazone plus EGCG co‐treatment dramatically increases cell's bone‐forming activity and bone‐like tissue production (
Ching‐Yun Chen, Jia‐Ci Jhang, Chun‐Yi Peng, Quốc Cường Nguyễn, Feng‐Huei Lin, Hung‐Ming Wu, Shankung Lin   +6 more
wiley   +1 more source

Clinical trial publication trends within neurology

Translational Neuroscience, 2019
Timely dissemination of results from clinical studies is crucial for the advancement of knowledge and clinical decision making. A large body of research has shown that up to half of clinical trials do not publish their findings.
Q. Duy Phan, Sreekrishnan Anirudh, David Wyatt, Paranjpe Manish D., Paranjpe Ishan, Sheth Amar, Gültekin Batur, Sheth Kevin N.   +7 more
doaj   +1 more source

Mini-CEX Sebagai Metode Penilaian Keterampilan Klinis Mahasiswa Program Pendidikan Kepaniteraan Klinik Fakultas Kedokteran Universitas Gadjah Mada - Studi Pendahuluan

Jurnal Pendidikan Kedokteran Indonesia, 2012
Background: Mini-CEX was developed to assess clinical skills by direct observation. Mini-CEX as a clinical skills assessment tool had to fulfill four requirements: validity, reliability, effects on students, and practicality. The purpose of this study is
Reza M. Munandar, Yoyo Suhoyo, Tridjoko Hadianto   +2 more
doaj   +1 more source

The role of lipid metabolism in neuronal senescence

FEBS Open Bio, EarlyView.
Disrupted lipid metabolism, through alterations in lipid species or lipid droplet accumulation, can drive neuronal senescence. However, lipid dyshomeostasis can also occur alongside neuronal senescence, further amplifying tissue damage. Delineating how lipid‐induced senescence emerges in neurons and glial cells, and how it contributes to ageing and ...
Dikaia Tsagkari, Eleftheria Panagiotidou, Nektarios Tavernarakis   +2 more
wiley   +1 more source

Medical students’ experience of emotions and success in neurological studies – What do they tell us?

BMC Medical Education, 2017
Background There is a need to develop effective educational experience in neurology to improve the students’ skills in diagnosing and managing patients with neurological symptoms or disease.
Hanna Ansakorpi, Marja-Liisa Sumelahti, Raimo Kaasila   +2 more
doaj   +1 more source