Results 201 to 210 of about 30,009 (273)

Precision therapies for genetic epilepsies in 2025: Promises and pitfalls

Epilepsia Open, EarlyView.
Abstract By targeting the underlying etiology, precision therapies offer an exciting paradigm shift to improve the stagnant outcomes of drug‐resistant epilepsies, including developmental and epileptic encephalopathies. Unlike conventional antiseizure medications (ASMs) which only treat the symptoms (seizures) but have no effect on the underlying ...
Shuyu Wang, Emilio Perucca, Samuel F. Berkovic, Piero Perucca   +3 more
wiley   +1 more source

Abnormal functional connectivity patterns in temporal lobe epilepsy—An international ENIGMA‐epilepsy study

Epilepsia Open, EarlyView.
Abstract Objectives Temporal lobe epilepsy (TLE) impacts multiple brain networks. Aberrant functional connectivity has been demonstrated in resting‐state networks (RSNs) that mediate higher brain functions in TLE. This study aimed to identify the reproducible patterns of altered functional connectivity in TLE in a large, international cohort through ...
Victoria Ives‐Deliperi, Jonathan Ipser, James T. Butler, Heath Pardoe, Hamid Soltanian‐Zadeh, Christian Rummel, Roland Wiest, Simon S. Keller, Barbara A. K. Kreilkamp, Anna Elisabetta Vaudano, Alice Ballerini, Stefano Meletti, Gerard Hall, Peter Taylor, Luis Concha, Alfonso Fajardo‐Valdez, Raphael Fernandes Casseb, Fernando Cendes, Clarissa L. Yasuda, Louis Lemieux, John S. Duncan, Esmaeil Davoodi‐Bodj, Orrin Devinsky, Sophia I. Thomopoulos, Dan J. Stein, Paul M. Thompson, Sanjay M. Sisodiya, Taha Gholipour, Carrie R. McDonald   +28 more
wiley   +1 more source

Systemic neuropsychology: toward a contemporary theory of topological functional systems. [PDF]

Front Psychiatry
Guiral JA.
europepmc   +1 more source

Unveiling sleep disturbances in KCNB1‐related disorders: Insights from a cohort of 78 individuals

Epilepsia Open, EarlyView.
Abstract Objectives Sleep disturbances are frequent comorbidities in epilepsies and developmental encephalopathies. This study aimed to characterize sleep abnormalities in individuals with KCNB1‐related disorders, focusing on their prevalence, clinical manifestations, and impact on daily functioning.
Giovanna Scorrano, Delphine Breuillard, Anais Thimon, Nicole Chemaly, Rima Nabbout   +4 more
wiley   +1 more source

Development and Preliminary Validation of ORCA-PD, an Online Rapid Cognitive Assessment for Parkinson Disease: Mixed Methods Study. [PDF]

J Med Internet Res
Lithwick Algon A, Brisman S, Lin CR, Saban W.   +3 more
europepmc   +1 more source

Beyond seizures: A multidimensional approach to non‐seizure issues in Lennox–Gastaut syndrome. Insights from Italian experts

Epilepsia Open, EarlyView.
Abstract Non‐seizure issues (NSIs), including cognition, behavior/psychiatric symptoms, adaptive and social functioning, sleep, autonomic, and motor impairments, often shape day‐to‐day outcomes in Lennox–Gastaut syndrome (LGS) more than seizures, yet clinicians lack LGS‐specific, feasible assessment pathways.
Giancarlo Di Gennaro, Domenica Immacolata Battaglia, Paolo Bonanni, Gian Marco Duma, Antonietta Coppola, Edoardo Ferlazzo, Dario Pruna, Carlo Di Bonaventura   +7 more
wiley   +1 more source

Correction to: Performance on the Hayling and Brixton tests in older adults: Norms and correlates. [PDF]

Arch Clin Neuropsychol
europepmc   +1 more source

Abnormal Forgetting Rate from the Recency Portion of a Word-List in Patients with Subjective Cognitive Decline. [PDF]

Arch Clin Neuropsychol
Leonardi C, Di Palma V, De Simone MS, Stanzione A, Rodini M, Caruso G, Covino S, Pugliese M, Caltagirone C, Carlesimo GA.   +9 more
europepmc   +1 more source

Occurrence and clinical correlates of depressive symptoms in adults with epilepsy: A study in Georgia

Epilepsia Open, EarlyView.
Abstract Objective To evaluate the occurrence, clinical correlates, and screening accuracy of depressive symptoms (DS) among adults with epilepsy in Georgia, a country with limited mental health resources. Methods We conducted a cross‐sectional study in adults with epilepsy attending a tertiary care center. We assessed DS using two validated tools: the
Ketevan Silagadze, Eka Burkadze, Maka Areshidze, Teimuraz Silagadze, Sofia Kasradze, Josemir W. Sander   +5 more
wiley   +1 more source

Correction: Adverse competition-related cognitions and it's relation to satisfaction and subjective performance: a validation study in a sample of English-speaking athletes. [PDF]

Sci Rep
Michel-Kröhler A, Wessa M, Berti S.
europepmc   +1 more source