Results 101 to 110 of about 1,464,129 (347)

Retrospective Analysis of Laryngeal Cancer Patients in a Tertiary Referral Center

Turkish Archives of Otorhinolaryngology
Objective: In this study, we aimed to evaluate the effects of demographic data and comorbid diseases on the prognosis and treatment diagnosed with laryngeal squamous cell cancer (LSCC).
Ali Can Sungur, Ömer Bayır, Gökhan Toptaş, Şevket Aksoy, Sevilay Karahan, Volkan Yücel, Emel Çadallı Tatar, Güleser Saylam, Mehmet Hakan Korkmaz   +8 more
doaj   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Clinical and Therapeutic Profile of Non-Hodgkin’s Lymphoma: A Retrospective Study From a Najran Oncology Center [PDF]

, 2023
Ahmed M Badheeb, Faisal Ahmed, Musadag Elhadi, Nasher H Alyami, Mohamed Badheeb   +4 more
openalex   +1 more source

Time after time – circadian clocks through the lens of oscillator theory

FEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo, Carolin Ector, Hanspeter Herzel   +2 more
wiley   +1 more source

Glucocorticoids in clinical oncology

Cleveland Clinic Journal of Medicine, 1992
Glucocorticoids have been used in clinical oncology for more than three decades. Their anti-inflammatory action plays a major role in their clinical applications in oncology. The incidence and severity of side effects depend on the total dose and the duration of therapy, but optimal dosages for these drugs have not been determined.
D, Walsh, J, Avashia
openaire   +2 more sources

Selection of Optimal Adjuvant Chemotherapy Regimens for Early Breast Cancer and Adjuvant Targeted Therapy for HER2-Positive Breast Cancers: An American Society of Clinical Oncology Guideline Adaptation of the Cancer Care Ontario Clinical Practice Guideline Summary [PDF]

, 2016
Neelima Denduluri, Mark R. Somerfield, Antonio C. Wolff   +2 more
openalex   +1 more source

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

Molecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero, Alejandro Belmonte‐Fernández, Mónica González‐Moreno, Laura Rodríguez‐Cordero, Begoña Pérez‐Valderrama, Joaquín Herrero‐Ruíz, Francisco Romero, Carmen Sáez, Miguel Á. Japón   +8 more
wiley   +1 more source

How did I experience ASCO 2021?

Iberoamerican Journal of Medicine, 2021
Adrián Pablo Huñis
doaj   +1 more source

Anxiety and depression among women with newly diagnosed vulvar cancer – A nationwide longitudinal study

Acta Obstetricia et Gynecologica Scandinavica
Introduction Our objective was to investigate the trajectories of anxiety, depression, emotional and social functioning in women with newly diagnosed vulvar cancer from the time of diagnosis to 12 months after treatment.
Diana Zach, Pernille T. Jensen, Henrik Falconer, Zuzana Kolkova, Katja Stenström Bohlin, Preben Kjølhede, Elisabeth Åvall Lundqvist, Angelique Flöter Rådestad   +7 more
doaj   +1 more source

Incidence and mortality of multiple myeloma in China, 2006–2016: an analysis of the Global Burden of Disease Study 2016

Journal of Hematology & Oncology, 2019
Background The accurate information about burden of multiple myeloma (MM) at national and provincial level remains unknown in China. Methods Following the general analytical strategy used in GBD 2016, the age-, sex-, and province-specific incidence and ...
Jiangmei Liu, Weiping Liu, Lan Mi, Xinying Zeng, Cai Cai, Jun Ma, Lijun Wang, Union for China Lymphoma Investigators of the Chinese Society of Clinical Oncology, Union for China Leukemia Investigators of the Chinese Society of Clinical Oncology   +8 more
doaj   +1 more source