Results 111 to 120 of about 1,464,129 (347)
Molecular Oncology, EarlyView.AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou +5 more
wiley +1 more source
Molecular Oncology, EarlyView.PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham +21 more
wiley +1 more source
Full Issue: Volume 13, Issue 1 - Winter 2018 [PDF]
, 2018 Full Issue: Volume 13, Issue 1 - Winter ...
core +1 more source
Molecular Oncology, EarlyView.This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan +9 more
wiley +1 more source
Focal Spot, Fall/Winter 1989 [PDF]
, 1989 https://digitalcommons.wustl.edu/focal_spot_archives/1053/thumbnail ...
core +1 more source
Ovarian Cancer, Version 1.2016, NCCN Clinical Practice Guidelines in Oncology [PDF]
, 2016 Robert J. Morgan +31 more
openalex +1 more source
Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology
Molecular Oncology, EarlyView.Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts +8 more
wiley +1 more source
Advances in Application of Federated Machine Learning for Oncology and Cancer Diagnosis
InformationMachine learning has brought about a revolutionary transformation in healthcare. It has traditionally been employed to create predictive models through training on locally available data.
Mohammad Nasajpour +7 more
doaj +1 more source
Neoadjuvant pazopanib and molecular analysis of tissue response in renal cell carcinoma
JCI Insight, 2020 BACKGROUND Surgery remains the frontline therapy for patients with localized clear cell renal cell carcinoma (ccRCC); however, 20%–40% recur. Angiogenesis inhibitors have improved survival in metastatic patients and may result in responses in the ...
Christopher G. Wood +16 more
doaj +1 more source