Results 121 to 130 of about 1,403,082 (309)

The impact of local symptoms on health‐related quality of life in vulvar cancer survivors—A nationwide prospective study

Acta Obstetricia et Gynecologica Scandinavica
Introduction Vulvar cancer may cause serious local symptoms that may impact negatively on the woman's health‐related quality of life (HRQOL). However, knowledge about the prevalence of vulvar and lymphedema symptoms at diagnosis and during follow‐up is ...
Diana Zach, Pernille T. Jensen, Henrik Falconer, Zuzana Kolkova, Katja Stenström Bohlin, Preben Kjølhede, Ivette Raices Cruz, Elisabeth Åvall‐Lundqvist, Angelique Flöter Rådestad   +8 more
doaj   +1 more source

Advances in the applications of monoclonal antibodies in clinical oncology. London, 28-30 May 1986 [PDF]

, 1986
Mike Clark, Richard J. Benjamin, C Bindon, Molly E. Bruggeman, Stephen Cobbold, Lisa K. Gilliland, G Hale, Suofu Qin, Helen Tighe, Herman Waldmann, Horace Sir, William G. Dunn, Mark Bodmer, Jefferson Foote, P. Simon Jones, P R Dear, Karol Sikora, Gérard I. Evan, Stephen Chan, Jonathan Stewart, James Watson   +20 more
openalex   +1 more source

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

Molecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero, Alejandro Belmonte‐Fernández, Mónica González‐Moreno, Laura Rodríguez‐Cordero, Begoña Pérez‐Valderrama, Joaquín Herrero‐Ruíz, Francisco Romero, Carmen Sáez, Miguel Á. Japón   +8 more
wiley   +1 more source

How did I experience ASCO 2021?

Iberoamerican Journal of Medicine, 2021
Adrián Pablo Huñis
doaj   +1 more source

Clinical features and outcome of T-cell acute lymphoblastic leukemia in childhood with respect to alterations at the TAL1 locus: a Pediatric Oncology Group study [PDF]

, 1993
RO Bash, WM Crist, JJ Shuster, MP Link, M Amylon, J Pullen, AJ Carroll, GR Buchanan, RG Smith, Richard Baer   +9 more
openalex   +1 more source

The critical role of DNA damage‐inducible transcript 4 (DDIT4) in stemness character of leukemia cells and leukemia initiation

Molecular Oncology, EarlyView.
Stemness properties, including quiescence, self‐renewal, and chemoresistance, are closely associated with leukemia relapse. Here, we demonstrate that DNA damage‐inducible transcript 4 (DDIT4) is induced in the hypoxic bone marrow niche and is essential for maintaining the stemness of AML1‐ETO9a leukemia cells.
Yishuang Li, Zhijie Cao, Haiyan Xing, Zhenya Xue, Wenbing Liu, Jiayuan Chen, Yihan Mei, Runxia Gu, Hui Wei, Shaowei Qiu, Min Wang, Qing Rao, Jianxiang Wang   +12 more
wiley   +1 more source

Focal Spot, Fall/Winter 1989 [PDF]

, 1989
https://digitalcommons.wustl.edu/focal_spot_archives/1053/thumbnail ...

core   +1 more source

Gemcitabine, ifosfamide, cisplatin (GIP) for the treatment of advanced non-small cell lung cancer: A phase II study of the Italian oncology group for clinical research (goirc) [PDF]

, 2000
C. Boni, Giancarlo Bisagni, Luisa Savoldi, Gabriella Moretti, Ermanno Rondini, M. Sassi, A. Zadro, Tommaso De Pas, Vittorio Franciosi, Antonio Pazzola, Rafael Vignoli, Maria Banzi, Vida Pajetta   +12 more
openalex   +2 more sources

Unveiling unique protein and phosphorylation signatures in lung adenocarcinomas with and without ALK, EGFR, and KRAS genetic alterations

Molecular Oncology, EarlyView.
Proteomic and phosphoproteomic analyses were performed on lung adenocarcinoma (LUAD) tumors with EGFR, KRAS, or EML4–ALK alterations and wild‐type cases. Distinct protein expression and phosphorylation patterns were identified, especially in EGFR‐mutated tumors. Key altered pathways included vesicle transport and RNA splicing.
Fanni Bugyi, Mirjam Balbisi, Simon Sugár, Lóránd Váncza, Eszter Regős, Ilona Kovalszky, Ibolya Laczó, Tünde Harkó, Gábor Kecskeméti, Zoltán Szabó, Judit Moldvay, László Drahos, Lilla Turiák   +12 more
wiley   +1 more source

Targeting of PTP4A3 overexpression sensitises HGSOC cells towards chemotherapeutic drugs

Molecular Oncology, EarlyView.
In HGSOC with normal KRAS expression, high PTP4A3 expression regulates autophagy activation. Conversely, in HGSOC with high KRAS expression, KRAS dictates autophagy control, and PTP4A3 is not required. When high PTP4A3 expression is inhibited, HGSOC cells are preferentially sensitised towards DNA‐damaging agents.
Ana López‐Garza, David James, Emma Creagh, James T. Murray   +3 more
wiley   +1 more source