Results 131 to 140 of about 10,004,929 (375)

Standardization of sequencing coverage depth in NGS: Recommendation for detection of clonal and subclonal mutations in cancer diagnostics [PDF]

, 2019
The insufficient standardization of diagnostic next-generation sequencing (NGS) still limits its implementation in clinical practice, with the correct detection of mutations at low variant allele frequencies (VAF) facing particular challenges. We address
Dýšková, Tereza, Kriegová, Eva, Novosad, Tomáš, Papajík, Tomáš, Petráčková, Anna, Schneiderová, Petra, Sedlaříková, Lenka, Vašinek, Michal   +7 more
core   +1 more source

How did I experience ASCO 2021?

Iberoamerican Journal of Medicine, 2021
Adrián Pablo Huñis
doaj   +1 more source

Incidence and mortality of multiple myeloma in China, 2006–2016: an analysis of the Global Burden of Disease Study 2016

Journal of Hematology & Oncology, 2019
Background The accurate information about burden of multiple myeloma (MM) at national and provincial level remains unknown in China. Methods Following the general analytical strategy used in GBD 2016, the age-, sex-, and province-specific incidence and ...
Jiangmei Liu, Weiping Liu, Lan Mi, Xinying Zeng, Cai Cai, Jun Ma, Lijun Wang, Union for China Lymphoma Investigators of the Chinese Society of Clinical Oncology, Union for China Leukemia Investigators of the Chinese Society of Clinical Oncology   +8 more
doaj   +1 more source

MET and NF2 alterations confer primary and early resistance to first‐line alectinib treatment in ALK‐positive non‐small‐cell lung cancer

Molecular Oncology, EarlyView.
Alectinib resistance in ALK+ NSCLC depends on treatment sequence and EML4‐ALK variants. Variant 1 exhibited off‐target resistance after first‐line treatment, while variant 3 and later lines favored on‐target mutations. Early resistance involved off‐target alterations, like MET and NF2, while on‐target mutations emerged with prolonged therapy.
Jie Hu, Ning Ding, Xiaobo Xu, Yedan Chen, Yong Zhang, Jingwen Liu, Jiebai Zhou, Hairong Bao, Donghui Zhang, Yijun Song, Yang Shao, Yuanlin Song   +11 more
wiley   +1 more source

Impact of the SPOP Mutant Subtype on the Interpretation of Clinical Parameters in Prostate Cancer. [PDF]

, 2018
Purpose: Molecular characterization of prostate cancer, including The Cancer Genome Atlas, has revealed distinct subtypes with underlying genomic alterations.
Alshalalfa, Mohammed, Barbieri, Christopher E., Davicioni, Elai, Den, Robert B., Erho, Nicholas, Jenkins, Robert B., Karnes, R. Jeffrey, Klein, Eric A., Liu, Deli, Ross, Ashley E., Rubin, Mark A., Sboner, Andrea, Schaeffer, Edward M., Shoag, Jonathan, Spratt, Daniel E., Takhar, Mandeep, Tomlins, Scott A., Trock, Bruce   +17 more
core   +1 more source

Tracking the 2015 Gastrointestinal Cancers Symposium: bridging cancer biology to clinical gastrointestinal oncology [PDF]

, 2015
The 2015 Gastrointestinal Cancers Symposium (San Francisco, CA, USA; January 15–17) is the world-class conference co-sponsored by the American Society of Clinical Oncology, the American Society for Radiation Oncology, the American Gastroenterological ...
Aprile, Giuseppe, Casagrande, Mariaelena, Cascinu, Stefano, FALOPPI, LUCA, Fasola, Gianpiero, Giampieri, Riccardo, Leone, Francesco, Marino, Donatella, SCARTOZZI, MARIO   +8 more
core   +1 more source

Clinical Oncology Society of Australia position statement on exercise in cancer care

Medical Journal of Australia, 2018
of The term physical activity applies to any movement produced by skeletal muscles that requires the body to exert energy. Exercise is structured physical activity for the purpose of conditioning the body to improve health and fi tness.
P. Cormie, Morgan Atkinson, Lucy L Bucci, A. Cust, E. Eakin, S. Hayes, Sandie McCarthy, A. Murnane, Sharni Patchell, D. Adams   +9 more
semanticscholar   +1 more source

Chemoresistome mapping in individual breast cancer patients unravels diversity in dynamic transcriptional adaptation

Molecular Oncology, EarlyView.
This study used longitudinal transcriptomics and gene‐pattern classification to uncover patient‐specific mechanisms of chemotherapy resistance in breast cancer. Findings reveal preexisting drug‐tolerant states in primary tumors and diverse gene rewiring patterns across patients, converging on a few dysregulated functional modules. Despite receiving the
Maya Dadiani, Gilgi Friedlander, Gili Perry, Nora Balint‐Lahat, Shlomit Gilad, Dana Morzaev‐Sulzbach, Anjana Shenoy, Noa Bossel Ben‐Moshe, Anya Pavlovsky, Rinat Bernstein‐Molho, Eytan Domany, Iris Barshack, Tamar Geiger, Bella Kaufman, Einav Nili Gal‐Yam   +14 more
wiley   +1 more source

Anxiety and depression among women with newly diagnosed vulvar cancer – A nationwide longitudinal study

Acta Obstetricia et Gynecologica Scandinavica
Introduction Our objective was to investigate the trajectories of anxiety, depression, emotional and social functioning in women with newly diagnosed vulvar cancer from the time of diagnosis to 12 months after treatment.
Diana Zach, Pernille T. Jensen, Henrik Falconer, Zuzana Kolkova, Katja Stenström Bohlin, Preben Kjølhede, Elisabeth Åvall Lundqvist, Angelique Flöter Rådestad   +7 more
doaj   +1 more source

Mortality of lymphoma and myeloma in China, 2004–2017: an observational study

Journal of Hematology & Oncology, 2019
Background There is a dearth of accurate information about patterns of mortality of lymphoid neoplasms and temporal trends in China. In this nationwide mortality study, we aimed to assess the mortality of lymphoma and myeloma in 2017 and the changes in ...
Weiping Liu, Jiangmei Liu, Yuqin Song, Xiaopei Wang, Maigeng Zhou, Lijun Wang, Jun Ma, Jun Zhu, Union for China Leukemia Investigators of the Chinese Society of Clinical Oncology, Union for China Lymphoma Investigators of the Chinese Society of Clinical Oncology   +8 more
doaj   +1 more source