Results 261 to 270 of about 10,004,929 (375)

Olaparib synergy screen reveals Exemestane induces replication stress in triple‐negative breast cancer

open access: yesMolecular Oncology, EarlyView.
Screening 166 FDA‐approved anticancer drugs identifies the aromatase inhibitor Exemestane as a synergistic partner of PARP inhibitor Olaparib in BRCA‐proficient triple‐negative breast cancer. Exemestane induces ROS‐mediated replication stress, enhancing DNA damage and apoptosis alongside Olaparib.
Nur Aininie Yusoh   +5 more
wiley   +1 more source

Japan society of clinical oncology position paper on appropriate clinical use of molecular residual disease (MRD) testing. [PDF]

open access: yesInt J Clin Oncol
Kobayashi S   +20 more
europepmc   +1 more source

Pericytes change function depending on glioblastoma vicinity: emphasis on immune regulation

open access: yesMolecular Oncology, EarlyView.
Pericytes alter their transcriptome depending on their proximity to the tumor core. In the tumor core, pericytes display a more active state with higher communication strength but with lower immune activation potential and a shift toward extracellular matrix production.
Carolina Buizza   +5 more
wiley   +1 more source

Analytical and Clinical Validation of Solo-Test Driver: A Targeted Amplicon-Based NGS Test-System for FFPE and cfDNA Analysis in Clinical Oncology Setting. [PDF]

open access: yesJ Clin Lab Anal
Ivanov M   +20 more
europepmc   +1 more source

American Society of Clinical Oncology Treatment of Unresectable Non–Small-Cell Lung Cancer Guideline: Update 2003 [PDF]

open access: bronze, 2003
David G. Pfister   +10 more
openalex   +1 more source

RKIP overexpression reduces lung adenocarcinoma aggressiveness and sensitizes cells to EGFR‐targeted therapies

open access: yesMolecular Oncology, EarlyView.
RKIP, a metastasis suppressor protein, modulates key oncogenic pathways in lung adenocarcinoma. In silico analyses linked low RKIP expression to poor survival. Functional studies revealed RKIP overexpression reduces tumor aggressiveness and enhances sensitivity to EGFR‐targeted therapies, while its loss promotes resistance.
Ana Raquel‐Cunha   +10 more
wiley   +1 more source

Chinese Society of Clinical Oncology (CSCO) Breast Cancer guidelines 2024. [PDF]

open access: yesTransl Breast Cancer Res
Li J   +16 more
europepmc   +1 more source

Is Patient Travel Distance Associated With Survival on Phase II Clinical Trials in Oncology? [PDF]

open access: bronze, 2003
Elizabeth B. Lamont   +9 more
openalex   +1 more source

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