Results 31 to 40 of about 1,247,370 (242)
Patient/Family Education for Newly Diagnosed Pediatric Oncology Patients [PDF]
There is a paucity of data to support evidence-based practices in the provision of patient/family education in the context of a new childhood cancer diagnosis.
Ahern, JoAnn+20 more
core +1 more source
Work stress and cancer researchers : an exploration of the challenges, experiences and training needs of UK cancer researchers. [PDF]
Work stress is a significant issue for many UK healthcare professionals, in particular those working in the field of oncology. However, there have been very few attempts to explore the challenges, experiences or training needs of researchers working in ...
Barnard+37 more
core +1 more source
Urine is a rich source of biomarkers for cancer detection. Tumor‐derived material is released into the bloodstream and transported to the urine. Urine can easily be collected from individuals, allowing non‐invasive cancer detection. This review discusses the rationale behind urine‐based cancer detection and its potential for cancer diagnostics ...
Birgit M. M. Wever+1 more
wiley +1 more source
Ablative therapy for people with localised prostate cancer : a systematic review and economic evaluation [PDF]
The research reported in this issue of the journal was funded by the HTA programme as project number 10/136/01. The contractual start date was in April 2012.
+233 more
core +3 more sources
Subpar reporting of pre‐analytical variables in RNA‐focused blood plasma studies
Pre‐analytical variables strongly influence the analysis of extracellular RNA (cell‐free RNA; exRNA) derived from blood plasma. Their reporting is essential to allow interpretation and replication of results. By evaluating 200 exRNA studies, we pinpoint a lack of reporting pre‐analytical variables associated with blood collection, plasma preparation ...
Céleste Van Der Schueren+16 more
wiley +1 more source
Ex Vivo Metrics™, a preclinical tool in new drug development [PDF]
Among the challenges facing translational medicine today is the need for greater productivity and safety during the drug development process. To meet this need, practitioners of translational medicine are developing new technologies that can facilitate ...
Gabbert, Helmut (Department of Pathology)+12 more
core +2 more sources
Cancer‐associated fibroblasts (CAFs) promote cancer growth, invasion (metastasis), and drug resistance. Here, we identified functional and diverse circulating CAFs (cCAFs) in patients with metastatic prostate cancer (mPCa). cCAFs were found in higher numbers and were functional and diverse in mPCa patients versus healthy individuals, suggesting their ...
Richell Booijink+6 more
wiley +1 more source
Molecular Diagnostics in Clinical Oncology
There are multiple applications of molecular tests in clinical oncology. Mutation analysis is now routinely utilized for the diagnosis of hereditary cancer syndromes. Healthy carriers of cancer-predisposing mutations benefit from tight medical surveillance and various preventive interventions.
Anna P. Sokolenko+5 more
openaire +4 more sources
Surfaceome: a new era in the discovery of immune evasion mechanisms of circulating tumor cells
In the era of immunotherapies, many patients either do not respond or eventually develop resistance. We propose to pave the way for proteomic analysis of surface‐expressed proteins called surfaceome, of circulating tumor cells. This approach seeks to identify immune evasion mechanisms and discover potential therapeutic targets. Circulating tumor cells (
Doryan Masmoudi+3 more
wiley +1 more source
The management of clinical emergencies in oncology
The incidence of cancer is remaining constant or slightly increasing in Europe. Due to screening programmes and better multi-modality treatment, the prevalence of cancer is significantly increasing. In addition, the aging population in Europe is rapidly rising.
Hoekstra, H.J., Wobbes, T.
openaire +4 more sources