Results 61 to 70 of about 1,403,082 (309)

Guidelines for analysis and reporting of clinical trials in oncology. [PDF]

open access: yes, 1993
When analyzing and reporting the results of clinical trials, investigators should follow a simple approach. The purpose of a trial is to estimate an effect or treatment difference, which if present would have clinical utility when treating new patients ...
Piantadosi, S, Saijo, N, Tamura, T
core  

Possibilities and realities of rehabilitation in cancer patients

open access: yesАкушерство, гинекология и репродукция, 2016
Development of methods of combined, radiation and medication therapy of malignant tumors has improved the results of survival, background of what is becoming a very important task of medical and social rehabilitation of patients.
A. G. Solopova   +3 more
doaj   +1 more source

Current Oncology: A Multidisciplinary Medium for Clinical Oncology

open access: yesCurrent Oncology, 2020
In recent years, the field of oncology has witnessed the unprecedented pace of genomics discovery, knowledge translation, and clinical research validation, which has led to novel systemic and locoregional therapeutics, an evolving role of immunotherapy ...
Sharlene Gill
doaj   +1 more source

Detecting homologous recombination deficiency for breast cancer through integrative analysis of genomic data

open access: yesMolecular Oncology, EarlyView.
This study develops a semi‐supervised classifier integrating multi‐genomic data (1404 training/5893 validation samples) to improve homologous recombination deficiency (HRD) detection in breast cancer. Our method demonstrates prognostic value and predicts chemotherapy/PARP inhibitor sensitivity in HRD+ tumours.
Rong Zhu   +12 more
wiley   +1 more source

Data‐driven discovery of gene expression markers distinguishing pediatric acute lymphoblastic leukemia subtypes

open access: yesMolecular Oncology, EarlyView.
This study investigates gene expression differences between two major pediatric acute lymphoblastic leukemia (ALL) subtypes, B‐cell precursor ALL, and T‐cell ALL, using a data‐driven approach consisting of biostatistics and machine learning methods. Following analysis of a discovery dataset, we find a set of 14 expression markers differentiating the ...
Mona Nourbakhsh   +8 more
wiley   +1 more source

ACR Accreditation for Utah Valley Hospital’s Radiation Oncology Center

open access: yes, 2019
Becoming an accredited clinic through the American College of Radiology (ACR) and their Radiation Oncology Practice Accreditation (ROPA) program will provide third-party evaluation of patient care to ensure the best treatment possible for patients.
Manigold, Remy
core   +1 more source

MicroRNA 196a contributes to the aggressiveness of esophageal adenocarcinoma through the MYC/TERT/NFκB axis

open access: yesMolecular Oncology, EarlyView.
mir‐196a promotes Esophagus Adenocarcinoma aggressiveness. On one hand, mir‐196a targets the valosin‐containing protein (VCP) mRNA, causing the accumulation of c‐MYC protein that leads to high amounts of TERT. On the other hand, mir‐196a targets the inhibitor of NFκB (NFKBIA).
Jesús García‐Castillo   +8 more
wiley   +1 more source

Metallopanstimulin as a marker for head and neck cancer [PDF]

open access: yes, 2004
BACKGROUND: Metallopanstimulin (MPS-1) is a ribosomal protein that is found in elevated amounts in the sera of patients with head and neck squamous cell carcinoma (HNSCC).
A Agrawal   +28 more
core   +4 more sources

The anticancer effect of the HDAC inhibitor belinostat is enhanced by inhibitors of Bcl‐xL or Mcl‐1 in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
The pan‐HDAC inhibitor belinostat increases the expression of the pro‐apoptotic proteins Bim, Puma, and Noxa and induces apoptosis in ovarian cancer cell lines and patient‐derived tumor organoids when used at high concentrations. Moreover, inhibiting the anti‐apoptotic proteins Bcl‐xL or Mcl‐1 sensitizes these preclinical models to the cytotoxic effect
Cécilia Thomine   +10 more
wiley   +1 more source

A Framework for Integrating Oncology Palliative Care in Doctor of Nursing Practice (DNP) Education [PDF]

open access: yes, 2018
Doctor of Nursing Practice (DNP) faculty play a critical role in preparing students to meet the complex needs of the nation as the number of cancer rates and survivors rise (National Cancer Institute, 2018) and as an unprecedented number of older ...
Breakwell, Susan   +4 more
core   +1 more source

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