Results 221 to 230 of about 24,824,508 (325)

Liquid biopsy biomarkers for cancer detection, treatment monitoring, and clinical outcome prediction. [PDF]

Front Cell Dev Biol
Batra A, Zheng X, Morgenstern-Kaplan D, Thomson CC, Lopes G, Jani C.   +5 more
europepmc   +1 more source

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

Molecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche, Niels J. van Ruitenbeek, Charlotte Adang, Luke O'Gorman, Pui Yuen Lee, Willemijn M. Klein, Adriana C. H. van Engen‐van Grunsven, Jack A. Schalken, Sander Bervoets, Gerald W. Verhaegh, Carla M. L. van Herpen   +10 more
wiley   +1 more source

Diagnostic Advancements in MINOCA: Do They Translate to a Better Clinical Outcome? A Review of the Literature. [PDF]

Medicina (Kaunas)
Bozika M, Apostolos A, Nastouli KM, Boliaris G, Sakalidis A, Ktenopoulos N, Karakasis P, Skalidis I, Konstantinou K, Mantzouranis E, Leontsinis I, Tsigkas G, Dimitriadis K, Tsioufis K, Panoulas V.   +14 more
europepmc   +1 more source

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

Molecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi, Tuan Khang Huynh, Adway Kadam, Zahra Kardan, Yue Yan, Amina Jamal Laham, Sampath Kumar Loganathan   +6 more
wiley   +1 more source

Meta-Analysis Should Not Be Simply Conducted By Default: Biologic Therapy for Chronic Obstructive Pulmonary Disease

COPD
Jean Bourbeau, Claudia LeBlanc, Bryan Ross, Darcy Marciniuk   +3 more
doaj   +1 more source

The effect of time-varying left ventricular ejection fraction on clinical outcome in critically ill COVID-19 patients. [PDF]

Ann Intensive Care
Chew MS, Jansson S, Jozwiak M, Hassanzadeh Z, Didriksson H, Jonsson C, Andersson H, Åström Aneq M, Slama M, Vieillard Baron A, Vignon P, Zhang H, Huang S.   +12 more
europepmc   +1 more source

Publishing anaesthetists' clinical outcomes [PDF]

Anaesthesia, 2016
openaire   +2 more sources

Partial FAK suppression promotes tumor growth, an effect reversed by macrophage p110δ PI3K inactivation

Molecular Oncology, EarlyView.
Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou, Niki Tzenaki, Anna Tsapara, Maria Tzardi, Evangelia A. Papakonstanti   +4 more
wiley   +1 more source

Clinical outcome of revisional gastrectomy postgastric banding failure: A systematic review. [PDF]

Medicine (Baltimore)
Rashdan M, Alzoubi R, Tarazi A, Abualrub R, Almanaseer Z, Alhashki H, Al Rekabat S.   +6 more
europepmc   +1 more source

Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer

Molecular Oncology, EarlyView.
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim, Maryam Aslam, Elouise Torruella, Alphons Sony, Asif Rahman, Simira Smith, Columba de la Parra, Moira Sauane   +7 more
wiley   +1 more source