Results 231 to 240 of about 24,824,508 (325)

Primary Tumor-Associated Loss of the Y Chromosome and Clinical Outcome in Metastatic Colorectal Cancer. [PDF]

Genes Chromosomes Cancer
Isnard A, Decraecker M, Fernandez B, Smith D, Dubus P, Dabernat S, Mansier O, Amintas S.   +7 more
europepmc   +1 more source

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

Molecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic, Rafael Stroggilos, Mladen Marinkovic, Ana Djuric, Suzana Stojanovic‐Rundic, Radmila Jankovic, Sergi Castellvi‐Bel, Remond J.A. Fijneman, Antonia Vlahou, Jerome Zoidakis, Milena Cavic   +10 more
wiley   +1 more source

Clinical Outcome and Safety of Amnioreduction in Singleton Pregnancies with Severe Polyhydramnios.

Fetal Diagn Ther
Grau L, Pérez-Cruz M, Bennassar M, Gómez O, Eixarch E, Masoller N, Izquierdo Renau M, Gratacós E, Martínez JM, Sabrià J.   +9 more
europepmc   +1 more source

The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer

Molecular Oncology, EarlyView.
Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad, Silvio Carlo Ermanno Tosatto, Emanuela Leonardi   +2 more
wiley   +1 more source

Benefits of targeted deployment of physician-led interprofessional pre-hospital teams on the care of critically ill and injured patients: a systematic review and meta-analysis

Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine
Adam J. Boulton, Terry Brown, Joyce Yeung   +2 more
doaj   +1 more source

End to end AI system for surgical gesture sequence recognition and clinical outcome prediction. [PDF]

NPJ Digit Med
Li X, Matsumoto N, Pasupulety U, Deo A, Yang C, Moran J, Hernandez ME, Wager P, Lin J, Kim J, Goh AC, Wagner C, Sonn GA, Hung AJ.   +13 more
europepmc   +1 more source

Gut microbiota alterations in patients with non‐small‐cell lung cancer undergoing chemoradiotherapy

Molecular Oncology, EarlyView.
We investigated the impact of concurrent chemoradiotherapy (CRT) on the gut microbiota in patients with locally advanced non‐small‐cell lung cancer. Overall gut microbiota composition remained largely stable throughout CRT while antibiotic exposure may influence microbial diversity.
Hanne Marte Nymoen, Zhi Zhao, Henrik Horndalsveen, Maria Moksnes Bjaanæs, Bjørn Henning Grønberg, Tarje Halvorsen, Tesfaye Madebo, Marianne Aanerud, Jussi Koivunen, Kersti Oselin, Saulius Cicenas, Nina Helbekkmo, Jarkko Ahvonen, Maria Silvoniemi, Tine Norman Alver, Tonje Dalen, Åsa Kristina Öjlert, Saima Jamil Farooqi, Åslaug Helland, Vilde Drageset Haakensen   +19 more
wiley   +1 more source

Dupilumab improves clinical outcome assessments in children with eosinophilic esophagitis in a randomized phase 3 study. [PDF]

BMC Gastroenterol
Chehade M, Spergel JM, Oliva S, Dellon ES, Ashok D, Rothenberg ME, Liu R, Louisias M, Radin A, Tilton ST, McCann E.   +10 more
europepmc   +1 more source

Extracellular vesicle lipidomics liquid biopsy reveals systemic and tumor microenvironment metabolic reprogramming in ovarian cancer

Molecular Oncology, EarlyView.
Extracellular vesicle (EV) lipidomic profiling of plasma and ascites from patients with high‐grade serous ovarian cancer and of ovarian cancer cell lines reveals enrichment of triglycerides (TGs), diacylglycerols (DGs), phosphatidylcholine (PCs), sphingomyelins (SMs), reflecting tumor metabolic reprogramming.
Shikha Rani, Dominic Guanzon, Andrew Lai, Katherin Scholz‐Romero, Sarah Reed, Edita Ritmejeryte, Rohan Lourie, Naven Chetty, Kaltin Ferguson, Carlos Salomon   +9 more
wiley   +1 more source

Therapies for alcohol use disorder in alcohol-associated hepatitis clinical trials: Integrated trial design with a composite clinical outcome as the primary endpoint. [PDF]

Hepatology
Dasarathy S, Karpyak VM, Arab JP, Singal AK, Simonetto DA, Brown ES, Tu W, Gawrieh S, and the AlcHepNet Investigators.   +8 more
europepmc   +1 more source