Results 271 to 280 of about 17,262,511 (380)

Tumor-infiltrating CD8+ lymphocytes predict clinical outcome in breast cancer.

Journal of Clinical Oncology, 2011
S. Mahmoud, E. Paish, D. Powe, R. Macmillan, M. Grainge, Andrew H. S. Lee, I. Ellis, A. Green   +7 more
semanticscholar   +1 more source

Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA

Molecular Oncology, EarlyView.
Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson, Anders Lade Nielsen, Boe Sandahl Sorensen   +2 more
wiley   +1 more source

Clinical Outcome and Prognostication of Patients With Inflammatory and Immune Myopathies With and Without Chemotherapy in the United States. [PDF]

Cureus
Singh B, Chen Y, Brar SK, Zakin E.
europepmc   +1 more source

Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting

Molecular Oncology, EarlyView.
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia, Noelia Moares, Wenjie Yi‐He, Rosa Luna‐Espejo, Ricardo Fernandez‐Cisnal, Javier Ocaña‐Cuesta, Juan P. Muñoz‐Miranda, Antonio Gabucio, Cecilia M. Fernandez‐Ponce, Francisco Garcia‐Cozar   +9 more
wiley   +1 more source

Benefits of targeted deployment of physician-led interprofessional pre-hospital teams on the care of critically ill and injured patients: a systematic review and meta-analysis

Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine
Adam J. Boulton, Terry Brown, Joyce Yeung   +2 more
doaj   +1 more source

Clinical features of pyogenic vertebral osteomyelitis and factors associated with adverse clinical outcome: a retrospective cohort study. [PDF]

BMC Infect Dis
Taysi MR, Acar A, Gezer Y, Tunc D, Yilmaz FA, Tarakci A, Altay FA, Sencan I.   +7 more
europepmc   +1 more source

Clinical Outcome Assessment [PDF]

, 2020
openaire   +1 more source

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

Molecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz, Anna L. Bartkowiak, Michael Rose, Nora Kolks, Patrick Petzsch, Vandana Solanki, Anne Stoffel, Bianca Faßbender, Leandra Lepping, Julka Volkamer, Karl Köhrer, Marc Seifert, Tokameh Mahmoudi, Tahlita C. M. Zuiverloon, Günter Niegisch, Michèle J. Hoffmann   +15 more
wiley   +1 more source

Enhanced recovery after surgery protocol implementation in pediatric Meckel's diverticulum resection: A clinical outcome study. [PDF]

World J Gastrointest Surg
Zhu K, Zhang X, Li Y, Gao Y, Tong YM, He JJ, Su YL.   +6 more
europepmc   +1 more source