Results 71 to 80 of about 17,262,511 (380)

Gender-based differences in platelet function and platelet reactivity to P2Y12 inhibitors.

PLoS ONE, 2019
BACKGROUND:Gender influences platelet biology. Women have a larger platelet count, but gender-based differences in platelet function remain debated.
Marco Ranucci, Tommaso Aloisio, Umberto Di Dedda, Lorenzo Menicanti, Carlo de Vincentiis, Ekaterina Baryshnikova, Surgical and Clinical Outcome REsearch (SCORE) group   +6 more
doaj   +1 more source

Epigenetics as a mechanism driving polygenic clinical drug resistance [PDF]

, 2006
Aberrant methylation of CpG islands located at or near gene promoters is associated with inactivation of gene expression during tumour development.
A Balmain, AJ Boivin, B Hendrich, BC Richardson, C Anacleto, C Grunau, CA Eads, E Bair, E Papouli, EE Cameron, F Lyko, G Egger, G Gifford, G Strathdee, G Strathdee, HG Chang, J Hall, J M Teodoridis, J Tra, JA Plumb, JF Costello, JG Herman, JM Teodoridis, JM Teodoridis, JP Issa, K Yamashita, L Zhang, LA Loeb, M Daskalakis, M Esteller, M Esteller, M Esteller, M Lachner, M Toyota, ME Valk-Lingbeek, MF Paz, MF Paz, MM Gottesman, MS Soengas, NP Bhattacharyya, PJ Johnson, PM Warnecke, R Agarwal, R Brown, R Brown, R M Glasspool, S Fulda, SH Wei, SH Wei, SL Gerson, SM Taylor, SW Lowe, T Taniguchi, T Ushijima, TH Huang, W Fischle, Y Pommier, Z Xiong   +57 more
core   +2 more sources

Dysphagia in Acute Stroke: Incidence, Burden and Impact on Clinical Outcome

PLoS ONE, 2016
Background Reported frequency of post-stroke dysphagia in the literature is highly variable. In view of progress in stroke management, we aimed to assess the current burden of dysphagia in acute ischemic stroke.
M. Arnold, Kai Liesirova, Anne Broeg-Morvay, J. Meisterernst, M. Schlager, M. Mono, M. El-Koussy, G. Kägi, Simon Jung, H. Sarikaya   +9 more
semanticscholar   +1 more source

Psychosocial Outcomes in Patients With Endocrine Tumor Syndromes: A Systematic Review

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Introduction The combination of disease manifestations, the familial burden, and varying penetrance of endocrine tumor syndromes (ETSs) is unique. This review aimed to portray and summarize available data on psychosocial outcomes in patients with ETSs and explore gaps and opportunities for future research and care.
Daniël Zwerus, Floortje Strobbe, Annemarie A. Verrijn Stuart, Hanneke M. van Santen, Gerlof D. Valk, Sasja A. Schepers, Rachel S. van Leeuwaarde   +6 more
wiley   +1 more source

Establishing meaningful change thresholds for European Organisation for Research and Treatment of Cancer Quality of Life Questionnaire CLL‐specific module domain scores: An analysis based on the TRANSCEND CLL 004 study in patients with relapsed or refractory chronic lymphocytic leukaemia or small lymphocytic lymphoma

eJHaem
Introduction The study aimed to establish meaningful thresholds at patient and group levels for the European Organisation for Research and Treatment of Cancer Quality of Life Questionnaire CLL‐specific module (EORTC QLQ‐CLL17) domain scores in adults ...
Laurie Eliason, Fatoumata Fofana, Lin Wang, Peter A. Riedell, Shien Guo   +4 more
doaj   +1 more source

CLINICAL OUTCOME OF STROKE PATIENTS BASED ON THE NATIONAL INSTITUTES OF HEALTH STROKE SCALE (NIHSS) IN A TERTIARY HOSPITAL

Malang Neurology Journal, 2022
Background: Stroke is the second leading cause of death and the third cause of disability globally. Clinical outcomes caused by stroke are varied and influenced by various factors.
Liunardo Bintang Pratama, Lisda Amalia, Cep Juli, Uni Gamayani, Asep Nugraha Hermawan   +4 more
doaj   +1 more source

“It’s hard to tell”. The challenges of scoring patients on standardised outcome measures by multidisciplinary teams: a case study of Neurorehabilitation [PDF]

, 2008
Background Interest is increasing in the application of standardised outcome measures in clinical practice. Measures designed for use in research may not be sufficiently precise to be used in monitoring individual patients.
A Bowling, A Colombo, A Garratt, A Skinner, A Strauss, AF Long, AF Long, AK Wagner, AM Epstein, B Kirshner, C Antaki, C Collin, C Jenkinson, CA McHorney, D Bilsker, EL Schor, FI Mahoney, H Houtkoop-Steenstra, HTO Davies, IJ Higginson, J Appleby, J Greenhalgh, J Greenhalgh, J Greenhalgh, J Slomka, J Verhoef, J Waterlow, JL Donovan, JM Geddes, K Charmaz, L Turner-Stokes, M Barkham, M Casper, M Slade, MB Callahan, MJ Westerman, NK Aaronson, P Atkinson, P Gompertz, R Fitzpatrick, R Fitzpatrick, R Flynn, R Flynn, RE Stake, RJ Lilford, RR Anspach, S Harrison, S Mallinson, S Novak, S Shah, S Tyson, S White, SD Messinger, SM Gilbody, T Delamothe   +54 more
core   +5 more sources

Nutritional and Behavioral Intervention for Long‐Term Childhood Acute Leukemia Survivors With Metabolic Syndrome

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Purpose Metabolic syndrome (MetS) is a common complication in survivors of childhood acute lymphoblastic and myeloid leukemia (AL), and a major risk factor for premature cardiovascular disease, type‐2‐diabetes, and metabolic dysfunction‐associated steatotic liver disease (MASLD).
Visentin Sandrine, Béliard Sophie, Renard Cécile, Caussy Cyrielle, Hamidou Zeinab, Romano David, Gacem Mélanie, Petit Arnaud, Saultier Paul, Borentain Patrick, Michel Gérard   +10 more
wiley   +1 more source

Survival for Children Diagnosed With Wilms Tumour (2012–2022) Registered in the UK and Ireland Improving Population Outcomes for Renal Tumours of Childhood (IMPORT) Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background The Improving Population Outcomes for Renal Tumours of childhood (IMPORT) is a prospective clinical observational study capturing detailed demographic and outcome data on children and young people diagnosed with renal tumours in the United Kingdom and the Republic of Ireland.
Naomi Ssenyonga, Angela Lopez‐Cortes, Reem Al‐Saadi, Suzanne Tugnait, Kristina Dzhuma, Catriona Duncan, Gordan Vujanic, Tanzina Chowdhury, Claudia Allemani, Michel P. Coleman, Kathy Pritchard‐Jones, the Children's Cancer and Leukaemia Group (CCLG) Renal Tumour Special Interest Group, Hugh Bishop, Anthony McCarthy, Pamela Kearns, Helen Rees, Amos Burke, Meriel Jenney, Jane Pears, Hamish Wallace, Milind Ronghe, Tanzina Chowdhury, Susan Picton, Emma Ross, Lisa Howell, Bernadette Brennan, Gail Halliday, Richard Grundy, Shaun Wilson, Sucheta Vaidya, Daniel Yeomanson, Jessica Bate, Vesna Pavasovic, Jessica Bate, Sabine Irtan, Jesper Brok, Minou Oostveen, Kristina Dzhuma, Mark Weeks, Richard Williams, Mark Powis, Max Pachl, Bruce Okoye, Naima Smeulders, Gordan Vujanic, Oystein Olsen, Tom Watson, Susan Shelmerdine, Dan Saunders, Angela Lopez-Cortes, Taryn Treger, Tom Jackson, Suzanne Tugnait, Lisa Howell, Tanzina Chowdhury, Sam Behjati, Angela Polanco   +56 more
wiley   +1 more source

Cerebrovascular complications and infective endocarditis. impact of available evidence on clinical outcome [PDF]

, 2018
Infective endocarditis (IE) is a life-threatening disease. Its epidemiological profile has substantially changed in recent years although 1-year mortality is still high.
De Bellis, Antonio, D’Abramo, Mizar, Frati, Giacomo, Greco, Ernesto, Iaccarino, Alessandra, Mestres, Carlos-A., Saade, Wael, Schirone, Leonardo, Sciarretta, Sebastiano   +8 more
core   +1 more source