Results 181 to 190 of about 2,569,145 (337)

How to select and understand guidelines for patient-reported outcomes: a scoping review of existing guidance

BMC Health Services Research
Background Over the past few decades, patient-reported outcomes (PROs) have been used to understand patient health conditions better. Therefore, numerous PRO measures (questionnaires) and guidelines or guidance have been developed.
Takako Kaneyasu, Eri Hoshino, Mariko Naito, Yoshimi Suzukamo, Kikuko Miyazaki, Satomi Kojima, Takuhiro Yamaguchi, Takashi Kawaguchi, Tempei Miyaji, Takako Eguchi Nakajima, Kojiro Shimozuma   +10 more
doaj   +1 more source

The importance of physical function as a clinical outcome: Assessment and enhancement. [PDF]

Clin Cardiol, 2020
O'Neill D, Forman DE.
europepmc   +1 more source

Standardized Antimicrobial Administration Ratio (SAAR) Clinical Outcomes Assessment in a Large Community Healthcare System [PDF]

, 2020
Hayley Burgess, Mandelin Cooper, Laurel Goldin, Kenneth Sands   +3 more
openalex   +1 more source

Gut microbiota diversity is prognostic in metastatic hormone receptor‐positive breast cancer patients receiving chemotherapy and immunotherapy

Molecular Oncology, EarlyView.
In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern, Kristian Holm, Nikolai Kragøe Andresen, Andreas Hagen Røssevold, Corinna Bang, Bjørn Naume, Johannes R. Hov, Jon Amund Kyte   +7 more
wiley   +1 more source

An evidence-based methodology for systematic evaluation of clinical outcome assessment measures for traumatic brain injury. [PDF]

PLoS One, 2020
Christoforou AN, Armstrong MJ, Bergin MJG, Robbins A, Merillat SA, Erwin P, Getchius TSD, McCrea M, Markowitz AJ, Manley GT, Giacino JT.   +10 more
europepmc   +1 more source

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

Molecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici, Soheil Akbari, Ceyda Caliskan, Canan Celiker, Ozden Oz, Leman Binokay, Gökhan Karakulah, Serif Senturk, Esra Erdal   +8 more
wiley   +1 more source

Development and evaluation of a computerized clinical outcome assessment tool for head and neck cancer patients. [PDF]

Medicine (Baltimore), 2020
Lin CR, Fan KH, Lin CY, Hung TM, Huang BS, Chen EY, Kang CJ, Huang SF, Chang JT, Chang CH.   +9 more
europepmc   +1 more source

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

Molecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert, Lauren van den Broecke, Osman Aksoy, Judith Lind, Sonia Vallet, Arne Van der Vreken, Gamze Ates, Ann Massie, Ken Maes, Kim De Veirman, Elke De Bruyne, Karin Vanderkerken, Klaus Podar, Eline Menu   +13 more
wiley   +1 more source

In vitro properties of patient serum predict clinical outcome after high dose rate brachytherapy of hepatocellular carcinoma

Molecular Oncology, EarlyView.
Following high dose rate brachytherapy (HDR‐BT) for hepatocellular carcinoma (HCC), patients were classified as responders and nonresponders. Post‐therapy serum induced increased BrdU incorporation and Cyclin E expression of Huh7 and HepG2 cells in nonresponders, but decreased levels in responders.
Lukas Salvermoser, Jan Niklas Schäfer, Shraga Nahum Goldberg, Philipp Maximilian Kazmierczak, Moritz Nikolaus Gröper, Philipp Franz Linden, Elif Öcal, Tanja Burkard, Stefanie Corradini, Najib Ben Khaled, Moritz Wildgruber, Max Seidensticker, Jens Ricke, Matthias Stechele, Marianna Alunni‐Fabbroni   +14 more
wiley   +1 more source

Brain Metastases of Non-Small Cell Lung Cancer: Magnetic Resonance Spectroscopy for Clinical Outcome Assessment in Patients with Stereotactic Radiotherapy. [PDF]

Onco Targets Ther, 2020
Jia C, Li Z, Guo D, Zhang Z, Yu J, Jiang G, Xing X, Ji S, Jin F.   +8 more
europepmc   +1 more source