Results 291 to 300 of about 2,569,145 (337)

Predictive Modeling of Hip Dislocation: Assessment of Surgical and Patient Factors to Reduce the Occurrence of Hip Instability and Adverse Clinical Outcomes

, 2018
D. Huff
openalex   +1 more source

The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity

Molecular Oncology, EarlyView.
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli, Alessio Bevilacqua, Mathias Wenes, Denis Migliorini, Lars van der Veen, Sigrid S Skånland, Giusy Di Conza, Kjetil Taskén   +7 more
wiley   +1 more source

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

Molecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta, Yang Song, Madeleine Ndahayo, Anirudh Saxena, Theresa Guo, Dylan Z. Kelley, Jessica Gore, Andrew Hennigan, Alexa Anderson, John C. Papadimitriou, Daria A. Gaykalova   +10 more
wiley   +1 more source

Outcome Assessment in Children and Adolescents With Chronic Pain: An International Clinical Practice Survey. [PDF]

Eur J Pain
Miró J, Sánchez-Rodríguez E, Jensen MP, Liossi C, Lord SM, Gobina I, Skidmore N, O'Keeffe M, Walker SM, de la Vega R, Ingelmo P, Koechlin H, Ståhl M, Stinson J, Wicksell RK, Finley GA, Cebrecos J, Goubert L, Reinoso-Barbero F, Rosenberger DC, Pogatzki-Zahn EM.   +20 more
europepmc   +1 more source

Microcephaly with Simplified Gyral Pattern in Children: Quantitative Morphometric Assessment on Brain MRI and Correlation with Clinical Outcome

Stefanie Chambers, Martins Monteiro, Yanniklas Kravutske, Lukas Haider, Gregor Kasprian, Ana Filipa Geraldo Md Msc Phd, Bruno P. Soares   +6 more
openalex   +1 more source

Development of a core outcome set for the assessment of spasticity in adults: a study protocol. [PDF]

Trials
Hill B, Ashford S, Barden H, Shaw L, Waters N, Williams G, Banky M.   +6 more
europepmc   +1 more source

Patient experience and clinical outcome assessment validity in amyotrophic lateral sclerosis: a targeted literature review

Sarah E. Curtis, Sophi Tatlock, Louise O’Hara, Ekin Seçinti, Nicole F. Mehdiyoun, Lara Ayala-Nunes, Jessica Flynn, Katherine Fernelius, Nicola Hodson, Laure Delbecque   +9 more
openalex   +1 more source

Augmenting virtual reality exposure for PTSD with physical activity: study protocol of a randomised controlled trial. [PDF]

Eur J Psychotraumatol
de Haart R, Daniels JK, Timmerman ME, Cath DC, Lommen MJJ.   +4 more
europepmc   +1 more source

Perceptions of healthcare quality indicators by anesthesiologists in intensive care departments in Ukraine. [PDF]

BMC Health Serv Res
Barsa M, Anufriyeva V.
europepmc   +1 more source